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    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇

    29-Norlanosta-8,24-diene-1alpha,2alpha,3beta-triol

    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇
    产品编号 CFN91990
    CAS编号 119765-92-3
    分子式 = 分子量 C29H48O3 = 444.69
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The herbs of Pongamia pinnata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇 CFN91990 119765-92-3 1mg QQ客服:1413575084
    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇 CFN91990 119765-92-3 5mg QQ客服:1413575084
    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇 CFN91990 119765-92-3 10mg QQ客服:1413575084
    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇 CFN91990 119765-92-3 20mg QQ客服:1413575084
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Mol Med Rep.2014, 9(5):1653-9
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  • Pharm Biol.2017, 55(1):360-366
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  • Bull. Pharm. Sci., Assiut University2020, 43(2):149-155.
  • Analytical Letters.2020, doi 10.1008
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  • Front Plant Sci.2020,11:630.
  • ...
  • 生物活性
    Description: 29-Norlanosta-8,24-diene-1alpha,2alpha,3beta-triol shows moderate cyctotoxic activity against PC-3 cell lines.
    In vitro:
    Chinese Traditional and Herbal Drugs, 2017, 48(5):853-858.
    Chemical constituents from Myrrha and their antitumor activities.[Reference: WebLink]
    To study the chemical constituents of Myrrha and their antitumor activities.
    METHODS AND RESULTS:
    The constituents were isolated and purified by recrystallization, and open silica gel, Sephadex LH-20, ODS column chromatography, as well as preparative HPLC. The structures were elucidated based on the chemical and spectroscopic methods. Furthermore, the cytotoxicities of these chemical components against PC-3 cell lines were measured by MTT method. Eleven compounds were obtained from the chloroform extract of myrrh, and were established as (4α,11α)-2-oxo-8,11-dihydroxycadina-1(6),7,9-trien-12-oic acid γ-lactone (1), (4α,11β)-2-oxo-8,11-dihydroxycadina-1(6),7,9-trien-12-oic acid γ-lactone (2), dihydropyrocurzerenone (3), orientalol E (4), guaianediol (5), cryptomeridiol (6), cycloartane-1α,2α,3β,25-tetrol (7), cycloartan-24-ene-1α,2α,3β-triol (8), cycloartan-24-ene-1α,3β-diol (9), 29-Norlanosta-8,24-diene-1alpha,2alpha,3beta-triol (10), and octadecane-1,2S,3S,4R-tetrol-1-O-α-L-rhamnopyranoside (11).
    CONCLUSIONS:
    Compounds 1 and 2 are two new compounds named as (+)-myrrhalactone A and (-)-myrrhalactone A, respectively. Compounds 4 and 6 are isolated from the genus Commiphora Engl. for the first time. Compounds 8, 10, and 11 show moderate cyctotoxic activity against PC-3 cell lines.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2488 mL 11.2438 mL 22.4876 mL 44.9752 mL 56.2189 mL
    5 mM 0.4498 mL 2.2488 mL 4.4975 mL 8.995 mL 11.2438 mL
    10 mM 0.2249 mL 1.1244 mL 2.2488 mL 4.4975 mL 5.6219 mL
    50 mM 0.045 mL 0.2249 mL 0.4498 mL 0.8995 mL 1.1244 mL
    100 mM 0.0225 mL 0.1124 mL 0.2249 mL 0.4498 mL 0.5622 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    24,25-二羟基环木菠萝烷-3-酮; 24,25-Dihydroxycycloartan-3-one CFN99653 155060-48-3 C30H50O3 = 458.7 5mg QQ客服:3257982914
    栀子花乙酸; Gardenolic acid B CFN96838 108864-53-5 C30H46O5 = 486.69 5mg QQ客服:1413575084
    黑升麻苷H-2; Cimicifugoside H2 CFN92972 161097-77-4 C35H54O10 = 634.8 5mg QQ客服:1457312923
    升麻酮醇-3-O-α-L-吡喃阿拉伯糖苷; Cimicidanol 3-O-alpha-L-arabinoside CFN90863 161207-05-2 C35H52O9 = 616.8 20mg QQ客服:1457312923
    黑升麻苷H-1; Cimicifugoside H1 CFN92973 163046-73-9 C35H52O9 = 616.78 5mg QQ客服:2932563308
    23-O-Acetylshengmanol 3-O-beta-D-xyloside; 23-O-Acetylshengmanol 3-O-beta-D-xyloside CFN92970 62498-88-8 C37H58O10 = 662.85 5mg QQ客服:1413575084
    (3beta,23E)-9,19-环羊毛甾-23-烯-3,25-二醇; Cycloart-23-ene-3,25-diol CFN90498 14599-48-5 C30H50O2 = 442.72 5mg QQ客服:2932563308
    (3beta,22E)-9,19-环羊毛甾-22-烯-3,25-二醇; Cycloart-22-ene-3,25-diol CFN97555 97456-49-0 C30H50O2 = 442.7 5mg QQ客服:2932563308
    环羊毛甾-24-烯-1alpha,2alpha,3beta-三醇; Cycloart-24-ene-1alpha,2alpha,3beta-triol CFN91991 942407-97-8 C30H50O3 = 458.72 5mg QQ客服:1457312923
    29-去甲羊毛甾-8,24-二烯-1alpha,2alpha,3beta-三醇; 29-Norlanosta-8,24-diene-1alpha,2alpha,3beta-triol CFN91990 119765-92-3 C29H48O3 = 444.69 5mg QQ客服:2932563308

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