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  • (+)-beta-柏木烯

    • (+)-beta-柏木烯

    (+)-beta-Cedrene

    (+)-beta-柏木烯
    		产品编号 CFN91636
    CAS编号 546-28-1
    分子式 = 分子量 C15H24 = 204.35
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Sesquiterpenoids
    植物来源 The heartwoods of Platycladus orientalis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    (+)-beta-柏木烯 CFN91636 546-28-1 1mg QQ客服：2056216494
    (+)-beta-柏木烯 CFN91636 546-28-1 5mg QQ客服：2056216494
    (+)-beta-柏木烯 CFN91636 546-28-1 10mg QQ客服：2056216494
    (+)-beta-柏木烯 CFN91636 546-28-1 20mg QQ客服：2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • MTT Agrifood Research Finland (Finland)
  • Universitas islam negeri Jakarta (Indonesia)
  • University of Oslo (Norway)
  • University of Pretoria (South Africa)
  • Leibniz Institute of Plant Biochemistry (Germany)
  • Medical University of South Carolina (USA)
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  • Universit?t Basel (Switzerland)
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  • Griffith University (Australia)
  • Nanjing University of Chinese Medicine (China)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Pharmacol.2021, 12:615157.
  • Molecules.2017, 22(12)
  • Chemistry of Natural Compounds2018, 204-206
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • J Sci Food Agric.2017, 97(5):1656-1662
  • Biochem Biophys Res Commun.2018, 505(1):194-200
  • Molecules.2019, 24(19):E3417
  • Journal of Ginseng Research2021, 25 November
  • Front Immunol. 2020, 11:62.
  • Int J Mol Sci.2019, 20(14):E3538
  • Environ Toxicol.2023, 23929.
  • Food Chem.2019, 278:683-691
  • Phytochem Anal.2016, 27(5):296-303
  • Plants (Basel).2020, 9(11):1535.
  • Plants (Basel).2023, 12(1):163.
  • Crystals2020, 10(3), 206.
  • J Med Food.2019, 22(10):1067-1077
  • J Agric Food Chem.2015, 63(44):9869-78
  • J Cell Mol Med.2022, 26(23):5807-5819.
  • Sci Rep.2015, 5:13194
  • J Separation Science & Technology2016, 51:1579-1588
  • Int J Mol Med.2020, 45(5):1514-1524.
  • J Chromatogr A.2017, 1518:46-58
  • ...
    • 生物活性
    Description: β-cedrene are bioactive sesquiterpenes found in cedar essential oil and exert antiseptic, anti-inflammatory, antispasmodic, tonic, astringent, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is a potent and competitive inhibitor of CYP2B6-mediated bupropion hydroxylase, and β-cedrene moderately blocks CYP3A4.
    In vivo:
    Physiol Behav . 2018 May 15;189:50-58.
    The anxiolytic effect of Juniperus virginiana L. essential oil and determination of its active constituents[Pubmed: 29326032]
    Essential oil from Juniperus virginiana L. (eastern red cedarwood essential oil, CWO) has been used to relax mind and enhance comfort for medical purposes. Few reports showed its effect on anxiety behaviors in animal models. The present study investigated the anxiolytic effect of CWO using two anxiety tests in mice, then determined the major active constituents, examined the change of neurotransmitters after intraperitoneal (i.p.) administration. Analysis using GC/MS revealed that the CWO contained (-)-α-cedrene (28.11%), (+)-β-cedrene (7.81%), (-)-thujopsene (17.71%) and (+)-cedrol (24.58%). CWO at 400-800mg/kg increased the percentage of open arm entries and the percentage of the time spent in open arms in the elevated plus maze (EPM), suggesting that the oil has anxiolytic effect. However, it didn't show anxiolytic effect in the light-dark box (LDB) test. Tests of the cedrene did not show anxiolytic effect in either test, but rather induced anxiety-related behaviors and inhibited the locomotor activity in EPM and LDB. Cedrol produced significant anxiolytic effect in both EPM and LDB tests at 400-1600mg/kg and 800-1600mg/kg, respectively. A more significant increase in locomotor activity was observed in cedrol at 200-1600mg/kg administration than CWO. CWO increased the 5-hydroxytryptamine (5-HT) concentration at 800mg/kg, whereas it didn't affect the dopamine (DA) concentration. Cedrol significantly reduced the DA level at 100-200mg/kg and elevated the 5-HT level at 1200-1600mg/kg. Moreover, it changed the ratio of 5-hydroxyindoleacetic acid/5-HT and 3, 4-dihydroxyphenyl acetic acid/DA at 1200-1600mg/kg. CWO and cedrol, in particular might act in an anxiolytic effect through the 5-HTnergic and DAnergic pathways.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.8936 mL 24.4678 mL 48.9356 mL 97.8713 mL 122.3391 mL
    5 mM 0.9787 mL 4.8936 mL 9.7871 mL 19.5743 mL 24.4678 mL
    10 mM 0.4894 mL 2.4468 mL 4.8936 mL 9.7871 mL 12.2339 mL
    50 mM 0.0979 mL 0.4894 mL 0.9787 mL 1.9574 mL 2.4468 mL
    100 mM 0.0489 mL 0.2447 mL 0.4894 mL 0.9787 mL 1.2234 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Binimetinib (MEK162); Binimetinib (MEK162) CFN60181 606143-89-9 C17H15BrF2N4O3 = 441.23 5mg QQ客服：2056216494
    萝卡辛; Raucaffricine CFN97762 31282-07-2 C27H32N2O8 = 512.56 5mg QQ客服：1413575084
    丹芝酸E; Ganolucidic acid E CFN95536 114567-50-9 C30H44O5 = 484.7 5mg QQ客服：2159513211
    Taxifolin 7-O-rhamnoside; Taxifolin 7-O-rhamnoside CFN96539 137592-12-2 C21H22O11 = 450.40 20mg QQ客服：1457312923

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