维采宁-3

Vicenin -3

	产品编号	CFN92032
	CAS编号	59914-91-9
	分子式 = 分子量	C₂₆H₂₈O₁₄ = 564.5
	产品纯度	>=98%
	物理属性	Yellow powder
	化合物类型	Flavonoids
	植物来源	The herbs of Chrysanthemi indici L.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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维采宁-3	CFN92032	59914-91-9	10mg	QQ客服：3257982914
维采宁-3	CFN92032	59914-91-9	20mg	QQ客服：3257982914
维采宁-3	CFN92032	59914-91-9	50mg	QQ客服：3257982914
维采宁-3	CFN92032	59914-91-9	100mg	QQ客服：3257982914

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

The Ohio State University (USA)

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Universitas islam negeri Jakarta (Indonesia)

University of Mysore (India)

Charles Sturt University (Denmark)

Nanjing University of Chinese Medicine (China)

University of Maryland School of Medicine (USA)

Tokyo Woman's Christian University (Japan)

University of Dicle (Turkey)

Aveiro University (Portugal)

Subang Jaya Medical Centre (Malaysia)

University of Malaya (Malaysia)

University of British Columbia (Canada)

Semmelweis Unicersity (Hungary)

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Description:

Tulsi and its flavonoids orientin and vicenin possess radioprotective effects. Orientin and vicenin can protect against foetal irradiation-induced genomic damage and instability, thereby reducing the delayed chromosomal abnormalities and tumorigenesis in adult.

In vitro:

J Pharm Biomed Anal . 2015 Jan;102:276-81.

Bioassay-guided preparative separation of angiotensin-converting enzyme inhibitory C-flavone glycosides from Desmodium styracifolium by recycling complexation high-speed counter-current chromatography[Pubmed: 25459924]

Abstract A new strategy of the convergence of high-speed counter-current chromatography (HSCCC) and bioactive assay technique was developed for rapidly screening and separating the angiotensin-converting enzyme (ACE) inhibitors from the aerial parts of Desmodium styracifolium. Bioactivity-guided fractionation of the crude extract was first established to target the bioactive fractions based on HSCCC coupled with in vitro ACE inhibitory assay. Subsequently, the bioactive fractions were further separated by the recycling complexation HSCCC respectively, using 0.10 mol/L copper sulfate in the lower phase of two-phase solvent system composed of n-butanol/water (1:1, v/v). Five C-glycosylflavones, vicenin 2 (1), carlinoside (2), vicenin 1 (3), schaftoside (4) and vicenin 3 (5), were successfully obtained. Their chemical structures were identified using ESI-MS and NMR. All the isolates showed in vitro ACE inhibitory activity with the IC50 values between 33.62 and 58.37 μM. The results demonstrated that the established method was proposed as an excellent strategy to systematically screen and purify active compounds from traditional Chinese medicines. Keywords: Angiotensin-converting enzyme inhibitor; Bioactivity-guided fractionation; C-flavone glycosides; Desmodium styracifolium; High-speed counter-current chromatography.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
乌药醇; Linderene	CFN90639	26146-27-0	C₁₅H₁₈O₂ = 230.3	10mg	QQ客服：1413575084
帕克醇; Parkeol	CFN92825	514-45-4	C₃₀H₅₀O = 426.7	5mg	QQ客服：2056216494
Moluccanin diacetate; Moluccanin diacetate	CFN99334	121700-27-4	C₂₄H₂₂O₁₀ = 470.4	5mg	QQ客服：3257982914
5,19-环氧-25-甲氧基南瓜-6,23-二烯-3-醇; 5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol	CFN97299	81910-39-6	C₃₁H₅₀O₃ = 470.7	5mg	QQ客服：2056216494

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7715 mL	8.8574 mL	17.7148 mL	35.4296 mL	44.287 mL
5 mM	0.3543 mL	1.7715 mL	3.543 mL	7.0859 mL	8.8574 mL
10 mM	0.1771 mL	0.8857 mL	1.7715 mL	3.543 mL	4.4287 mL
50 mM	0.0354 mL	0.1771 mL	0.3543 mL	0.7086 mL	0.8857 mL
100 mM	0.0177 mL	0.0886 mL	0.1771 mL	0.3543 mL	0.4429 mL