
(+)-花旗松素
(+)-Taxifolin
|
产品编号 |
CFN99183 |
CAS编号 |
17654-26-1 |
分子式 = 分子量 |
C15H12O7 = 304.25 |
产品纯度 |
>=98% |
物理属性 |
Powder |
化合物类型 |
Flavonoids |
植物来源 |
The herbs of Silybum marianum (L.) Gaertn. |
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
(+)-花旗松素 |
CFN99183 |
17654-26-1 |
10mg |
QQ客服:3257982914 |
(+)-花旗松素 |
CFN99183 |
17654-26-1 |
20mg |
QQ客服:3257982914 |
(+)-花旗松素 |
CFN99183 |
17654-26-1 |
50mg |
QQ客服:3257982914 |
(+)-花旗松素 |
CFN99183 |
17654-26-1 |
100mg |
QQ客服:3257982914 |
1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。
2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。
3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
订购流程
1. 在线订购
请联系我们QQ客服
2. 电话订购
请拨打电话:
027-84237683 或 027-84237783
3. 邮件或传真订购
发送电子邮件到: manager@chemfaces.com 或
发送传真到:027-84254680
提供订购信息
为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
1. 产品编号(CAS No.或产品名称)
2. 发货地址
3. 联系方法 (联系人,电话)
4. 开票抬头 (如果需要发票的客户)
5. 发票地址(发货地址与发票地址不同)
发货时间
1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。
2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。
3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
Universiti Kebangsaan Malaysia (Malaysia)
Centralised Purchases Unit (CPU), B.I.T.S (India)
Gyeongsang National University (Korea)
University of Hertfordshire (United Kingdom)
Max-Planck-Insitut (Germany)
Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
CSIRO - Agriculture Flagship (Australia)
Universidad de Buenos Aires (Argentina)
Universitas Airlangga (Indonesia)
Universidade Católica Portuguesa (Portugal)
Max Rubner-Institut (MRI) (Germany)
Sant Gadge Baba Amravati University (India)
Agricultural Research Organization (ARO) (Israel)
Ateneo de Manila University (Philippines)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
Description: |
(+)-Taxifolin is an inhibitor of aggregation of the 42-residue amyloid β-protein, it has preventive effects against Alzheimer's disease-like pathogenesis in vivo. It is also a weak inhibitor of cytochrome b5 reduction (IC50=9.8μM). |
Targets: |
Beta Amyloid |
In vitro: |
Toxicology. 2013 Jun 7;308:34-40. | In vitro effects of myricetin, morin, apigenin, (+)-taxifolin, (+)-catechin, (-)-epicatechin, naringenin and naringin on cytochrome b5 reduction by purified NADH-cytochrome b5 reductase.[Pubmed: 23567315 ] | The microsomal NADH-dependent electron transport system consisting of cytochrome b5 reductase and cytochrome b5 participates in a number of physiologically important processes including lipid metabolism as well as is involved in the metabolism of various drug and xenobiotics. METHODS AND RESULTS: In the present study, we assessed the inhibitory effects of eight dietary flavonoids representing five distinct chemical classes on cytochrome b5 reduction by purified cytochrome b5 reductase. From the flavonoids tested, myricetin was the most potent in inhibiting cytochrome b5 reduction with an IC50 value of 0.35μM. Myricetin inhibited b5 reductase noncompetitively with a Ki of 0.21μM with respect to cofactor NADH, and exhibited a non-linear relationship indicating non-Michaelis-Menten kinetic binding with respect to cytochrome b5. In contrast to the potent inhibitory activity of myricetin, (+)-Taxifolin was found to be a weak inhibitor (IC50=9.8μM). The remaining flavonoids were inactive within the concentration range tested (1-50μM). Analysis of structure-activity data suggested that simultaneous presence of three OH groups in ring B is a primary structural determinant for a potent enzyme inhibition. CONCLUSIONS: Our results suggest that inhibition of the activity of this system by myricetin or myricetin containing diets may influence the metabolism of therapeutic drugs as well as detoxification of xenobiotics. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
1 mM |
3.2868 mL |
16.4339 mL |
32.8677 mL |
65.7354 mL |
82.1693 mL |
5 mM |
0.6574 mL |
3.2868 mL |
6.5735 mL |
13.1471 mL |
16.4339 mL |
10 mM |
0.3287 mL |
1.6434 mL |
3.2868 mL |
6.5735 mL |
8.2169 mL |
50 mM |
0.0657 mL |
0.3287 mL |
0.6574 mL |
1.3147 mL |
1.6434 mL |
100 mM |
0.0329 mL |
0.1643 mL |
0.3287 mL |
0.6574 mL |
0.8217 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
部分图片展示
联系方式
电机:027-84237783
传真:027-84254680
在线QQ: 1413575084
E-Mail:manager@chemfaces.com
湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房

ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证
天然化合物与对照品的研发和生产。