白藜芦醇-4'-O-葡萄糖苷

Resveratroloside

	产品编号	CFN93239
	CAS编号	38963-95-0
	分子式 = 分子量	C₂₀H₂₂O₈ = 390.38
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源	The herbs of Rheum maximowiczii
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
白藜芦醇-4'-O-葡萄糖苷	CFN93239	38963-95-0	1mg	QQ客服：2159513211
白藜芦醇-4'-O-葡萄糖苷	CFN93239	38963-95-0	5mg	QQ客服：2159513211
白藜芦醇-4'-O-葡萄糖苷	CFN93239	38963-95-0	10mg	QQ客服：2159513211
白藜芦醇-4'-O-葡萄糖苷	CFN93239	38963-95-0	20mg	QQ客服：2159513211

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

University of Medicine and Pharmacy (Romania)

John Innes Centre (United Kingdom)

University of Padjajaran (Indonesia)

Heinrich-Heine-University Düsseldorf (Germany)

Charles Sturt University (Denmark)

Centralised Purchases Unit (CPU), B.I.T.S (India)

Wroclaw Medical University (Poland)

University of Perugia (Italy)

Centrum Menselijke Erfelijkheid (Belgium)

University of Ioannina (Greece)

Leibniz Institute of Plant Biochemistry (Germany)

Donald Danforth Plant Science Center (USA)

Kyoto University (Japan)

Regional Crop Research Institute (Korea)

More...

Description:

Resveratroloside has cardioprotective effect, it exhibits α-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4. Resveratroloside has anti-inflammatory activity, it shows similar nitric oxide (NO) inhibition potency as that of piceid (the major constituent of P. cuspidatum).

Targets:

NO | P450 (e.g. CYP17)

In vitro:

J Tradit Complement Med. 2013 Jul;3(3):182-7.

Anti-inflammatory Activity of the Invasive Neophyte Polygonum Cuspidatum Sieb. and Zucc. (Polygonaceae) and the Chemical Comparison of the Invasive and Native Varieties with regard to Resveratrol.[Pubmed: 24716176]

Polygonum cuspidatum Sieb. and Zucc. has been traditionally used as a member of many anti-inflammatory polyherbal formulations, but is now a widespread invasive neophyte in Europe and America.
METHODS AND RESULTS:
To discuss if the invasive variety is chemically identical to the native one in traditional medicine, the different constituents of the invasive variety compared to the native variety were isolated and their anti-inflammatory activity was tested. Resveratroloside and catechin-(4α→8)-catechin, the newly found constituents in the invasive variety, have similar nitric oxide (NO) inhibition potency as that of piceid (the major constituent of P. cuspidatum), but the newly found major constituent, i.e., piceatannol glucoside, showed no apparent effect. On the other hand, as a marker, the total content of resveratrol in the methanol root extract after glucosidase hydrolysis was measured and compared between the invasive and native varieties.
CONCLUSIONS:
The total content of resveratrol measured in the root extracts of the Swiss sample was about 2.5 times less than that of the Chinese one. This study brings attention to the point that when the invasive variety of P. cuspidatum is used in traditional medicine, the chemical difference should be kept in mind.

In vivo:

Cardiovasc Hematol Agents Med Chem. 2013 Sep;11(3):207-10.

Cardioprotective effect of resveratrol and resveratroloside.[Pubmed: 23547903]

METHODS AND RESULTS:
Cardioprotective effect of resveratrol and Resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received Resveratroloside).
CONCLUSIONS:
The cardioprotective effect of Resveratroloside was detected for the first time.

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5616 mL	12.808 mL	25.6161 mL	51.2321 mL	64.0402 mL
5 mM	0.5123 mL	2.5616 mL	5.1232 mL	10.2464 mL	12.808 mL
10 mM	0.2562 mL	1.2808 mL	2.5616 mL	5.1232 mL	6.404 mL
50 mM	0.0512 mL	0.2562 mL	0.5123 mL	1.0246 mL	1.2808 mL
100 mM	0.0256 mL	0.1281 mL	0.2562 mL	0.5123 mL	0.6404 mL

白藜芦醇-4'-O-葡萄糖苷

Resveratroloside

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