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  • Puerol A

    Puerol A

    Puerol A
    产品编号 CFN96269
    CAS编号 152784-32-2
    分子式 = 分子量 C17H14O5 = 298.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The stem barks of Sophora japonica.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Puerol A CFN96269 152784-32-2 1mg QQ客服:3257982914
    Puerol A CFN96269 152784-32-2 5mg QQ客服:3257982914
    Puerol A CFN96269 152784-32-2 10mg QQ客服:3257982914
    Puerol A CFN96269 152784-32-2 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universit?t Basel (Switzerland)
  • University of Zurich (Switzerland)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • University of Mysore (India)
  • Wroclaw Medical University (Poland)
  • Institute of Bioorganic Chemistry Polish Academy of Sciences (Poland)
  • University of Auckland (New Zealand)
  • University of Toronto (Canada)
  • Mahatma Gandhi University (India)
  • Siksha O Anusandhan University (India)
  • Ain Shams University (Egypt)
  • Kitasato University (Japan)
  • Biotech R&D Institute (USA)
  • Harvard University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Biol Pharm Bull.2021, 44(12):1891-1893.
  • Nutrients.2022, 14(23):4997.
  • Nutrients.2019, 11(11):E2694
  • Genes Genomics.2020, 10.1007
  • Environ Toxicol.2023, 38(5):1174-1184.
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • J Nat Prod.2022, 85(5):1351-1362.
  • Research Square2022, rs.3.rs-1948239
  • Front Pharmacol.2022, 13:906763.
  • Viruses.2017, 9(10)
  • Rep.Grant.Res.,Asahi Glass Foun.2023, No.119.
  • Molecules.2023, 28(8):3474.
  • ACS Pharmacol. Transl. Sci.2023, 3c00129.
  • Metabolites2023, 13(1), 3.
  • Biomed Pharmacother.2020, 128:110318.
  • Int J Biol Macromol.2018, 112:1093-1103
  • Food Res Int.2019, 123:125-134
  • Biochem Biophys Res Commun.2021, 534:802-807.
  • J Korean Soc Food Sci Nutr2020, doi: 10.3746.
  • Nutrients.2019, 11(4):E936
  • Int J Biol Macromol.2019, 126:653-661
  • Front Pharmacol.2021, 12:764297.
  • Int J Mol Sci.2020, 21(19):7209.
  • ...
  • 生物活性
    Description: Puerol A exhibits potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM. dl-Puerol A has antioxdiant activity, it shows inhibitory effects on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro.
    Targets: Aldose reductase
    In vitro:
    Oriental Pharmacy and Experimental Medicine,2004,4(3):211-4.
    Inhibitory effects of dl-Puerol A in the root of Sophora japonica on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro[Reference: WebLink]

    METHODS AND RESULTS:
    The inhibitory effect of dl-Puerol A as but-2-enolide isolated from Sophora japonica was investigated on copper ion-induced protein oxidative modification in vitro. It inhibited copper-induced protein oxidative modification. However, its inhibitory effect was a little weaker than that of as an antioxidant.
    CONCLUSIONS:
    The results demonstrated that dl-Puerol A, one of but-2-enolides, might be of use in the oxidative stress.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3523 mL 16.7616 mL 33.5233 mL 67.0466 mL 83.8082 mL
    5 mM 0.6705 mL 3.3523 mL 6.7047 mL 13.4093 mL 16.7616 mL
    10 mM 0.3352 mL 1.6762 mL 3.3523 mL 6.7047 mL 8.3808 mL
    50 mM 0.067 mL 0.3352 mL 0.6705 mL 1.3409 mL 1.6762 mL
    100 mM 0.0335 mL 0.1676 mL 0.3352 mL 0.6705 mL 0.8381 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Puerol B; Puerol B CFN95155 112343-17-6 C18H16O5 = 312.3 5mg QQ客服:215959384
    Specioside B; Specioside B CFN95165 126589-95-5 C23H24O10 = 460.4 5mg QQ客服:2056216494
    葛根苷A; Pueroside A CFN95177 100692-52-2 C29H34O14 = 606.6 5mg QQ客服:1457312923
    葛根苷C; Pueroside C CFN95156 112343-16-5 C24H26O10 = 474.5 5mg QQ客服:1457312923
    葛根苷B; Pueroside B CFN95141 100692-54-4 C30H36O15 = 636.6 10mg QQ客服:2159513211
    构树宁B; Broussonin B CFN97695 73731-86-9 C16H18O3 = 258.32 10 mg QQ客服:2159513211
    构树宁A; Broussonin A CFN97694 73731-87-0 C16H18O3 = 258.32 5mg QQ客服:1413575084
    构树宁C; Broussonin C CFN97690 76045-49-3 C20H24O3 = 312.41 5mg QQ客服:2159513211
    1-(4-羟基-2-甲氧基苯基)-3-(4-羟基-3-异戊烯基苯基)丙烷; 1-(4-Hydroxy-2-methoxyphenyl)-3-(4-hydroxy-3-prenylphenyl)propane CFN98607 376362-03-7 C21H26O3 = 326.4 5mg QQ客服:215959384
    1-羟基-1-(4-羟基-2-甲氧基苯基)-3-(4-羟基苯基)-2-丙酮; 1-Hydroxy-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)propan-2-one CFN97846 117614-84-3 C16H16O5 = 288.3 5mg QQ客服:2159513211

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