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  • 尼泊金丙酯

    Propyl paraben

    尼泊金丙酯
    产品编号 CFN70226
    CAS编号 94-13-3
    分子式 = 分子量 C10H12O3 = 180.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    尼泊金丙酯 CFN70226 94-13-3 10mg QQ客服:2159513211
    尼泊金丙酯 CFN70226 94-13-3 20mg QQ客服:2159513211
    尼泊金丙酯 CFN70226 94-13-3 50mg QQ客服:2159513211
    尼泊金丙酯 CFN70226 94-13-3 100mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
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    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
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    PMID: 28005066

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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Heinrich Heine University Dusseldorf2021, 62203.
  • PLoS One.2017, 12(8):e0181191
  • Integr Cancer Ther.2018, 17(3):832-843
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  • Molecules.2019, 24(6):E1177
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  • Heliyon2020, 6(6):e04337.
  • BMB Rep.2020, 53(4):218-222.
  • Front Pharmacol.2017, 8:205
  • Int J Mol Sci.2024, 25(6):3390.
  • Jeju National University Graduate School2023, 24478
  • Phytother Res.2022, 10.1002:ptr.7602.
  • Chem Res Toxicol. 2022, acs.chemrestox.2c00049.
  • Foods.2022, 11(12):1708.
  • J Chem Inf Model.2021, 61(11):5708-5718.
  • Arch Biochem Biophys.2020, 687:108384.
  • ...
  • 生物活性
    Description: Propyl paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years.
    Targets: Antifection
    In vitro:
    Journal of Antimicrobial Chemotherapy,2005,55(6):1013–1015.
    Propyl paraben induces potassium efflux in Escherichia coli.[Reference: WebLink]
    Parabens are currently used as antibacterial preservatives in pharmaceutical, cosmetic and food products but there are no precise data concerning their activity on bacterial membranes.
    METHODS AND RESULTS:
    We analysed the cytoplasmic potassium release during propyl paraben addition by using a selective electrode. Various conditions were assayed to investigate the bacterial paraben susceptibility. We compared the activity of propyl paraben with the activities of colicin A and polymyxin B. Propyl paraben induced potassium efflux that was related to the porin expression in the bacterial outer membrane. In addition, the presence of spermine, previously described as an efficient OmpF channel-blocker, protected susceptible cells against paraben activity.
    CONCLUSIONS:
    Propyl paraben induced potassium release in susceptible Escherichia coli cells similar to that observed with polymyxin B. Moreover, this efflux depended on porin channel activity. This permeabilizing effect is probably related to antibacterial properties of paraben molecules.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.5494 mL 27.7469 mL 55.4939 mL 110.9878 mL 138.7347 mL
    5 mM 1.1099 mL 5.5494 mL 11.0988 mL 22.1976 mL 27.7469 mL
    10 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
    50 mM 0.111 mL 0.5549 mL 1.1099 mL 2.2198 mL 2.7747 mL
    100 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Mesuol; Mesuol CFN96288 16981-20-7 C24H24O5 = 392.5 5mg QQ客服:2159513211
    地肤子皂苷II; Momordin II CFN92562 95851-41-5 C47H74O18 = 927.1 5mg QQ客服:215959384
    Glucocamelinin; Glucocamelinin CFN00501 67884-10-0 C18H34KNO10S3 = 559.8 5mg QQ客服:3257982914
    Pimentol; Pimentol CFN90573 141913-95-3 C23H26O12 = 494.5 5mg QQ客服:2159513211

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