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  • 没食子酸丙酯

    Propyl gallate

    没食子酸丙酯
    产品编号 CFN93164
    CAS编号 121-79-9
    分子式 = 分子量 C10H12O5 = 212.20
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 From Rhus chinensis Mill.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    没食子酸丙酯 CFN93164 121-79-9 10mg QQ客服:2056216494
    没食子酸丙酯 CFN93164 121-79-9 20mg QQ客服:2056216494
    没食子酸丙酯 CFN93164 121-79-9 50mg QQ客服:2056216494
    没食子酸丙酯 CFN93164 121-79-9 100mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Uniwersytet Gdański (Poland)
  • University of Fribourg (Switzerland)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • University of Toronto (Canada)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • University of Perugia (Italy)
  • Universiti Sains Malaysia (Malaysia)
  • Sri Ramachandra University (India)
  • Agricultural Research Organization (ARO) (Israel)
  • University of Sao Paulo (Brazil)
  • Monash University (Australia)
  • University of Toulouse (France)
  • Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)
  • Siksha O Anusandhan University (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Horticulturae2020, 6(4),76.
  • J Cosmet Dermatol.2022, 21(1):396-402.
  • Phytochem Anal.2023, pca.3305.
  • J Biotechnol.2020, 318:10-19.
  • Cancers (Basel).2021, 13(17):4327.
  • Sichuan Agricultural University2023, 4630743.
  • Eur J Pharmacol.2020, 889:173589.
  • Nature Ecology & Evolution2020, doi: 10.1038
  • Food and Bioprocess Technology2017, 10(6):1074-1092
  • Sci Rep.2023, 13(1):14594.
  • Pest Manag Sci.2019, 75(9):2530-2541
  • Aquaculture2019, 510:392-399
  • Applied Physics B2021, 127(92).
  • Industrial Crops and Products2022, 188:115638
  • Preprints2017, 2017120176
  • Appl. Sci.2020, 10(4),1304
  • Molecules.2019, 24(2):E343
  • ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
  • J Cell Mol Med.2022, 26(23):5807-5819.
  • J Chem Inf Model.2021, 61(11):5708-5718.
  • Industrial Crops and Products2022, 186:115298
  • Front Pharmacol.2019, 10:1025
  • Journal of Apiculture2023.38(3):249-254.
  • ...
  • 生物活性
    Description: Propyl gallate shows antioxidant,and hepatoprotective activities, it can potently inhibit diphenolase activity of tyrosinase. Propyl gallate inhibits the growth of HeLa cells via regulating intracellular GSH level,it also shows inhibitory effects on selected food-borne bacteria.
    Targets: SOD | ROS
    In vitro:
    Letters in Applied Microbiology, 1993, 17(1):29-32.
    Growth-Inhibition of Selected Food-Borne Bacteria by Tannic-Acid, Propyl Gallate and Related-Compounds[Reference: WebLink]

    METHODS AND RESULTS:
    Tannic acid, Propyl gallate, gallic acid and ellagic acid were tested for their inhibitory effects on selected food-borne bacteria by the well assay technique.
    CONCLUSIONS:
    Tannic acid and Propyl gallate were inhibitory whereas gallic acid and ellagic acid were not.
    J Agric Food Chem. 2003 Feb 12;51(4):1077-80.
    Sequestering ability of butylated hydroxytoluene, propyl gallate, resveratrol, and vitamins C and E against ABTS, DPPH, and hydroxyl free radicals in chemical and biological systems.[Pubmed: 12568575 ]
    The antioxidant capacity of butylated hydroxytoluene (BHT; 2,6-di-tert-butyl-p-cresol), Propyl gallate (3,4,5-trihydroxybenzoic acid n-propyl ester), resveratrol (trans-3,4',5-trihydroxystilbene), and vitamins C (l-ascorbic acid) and E [(+)-alpha-tocopherol] was studied in chemical and biological systems.
    METHODS AND RESULTS:
    The chemical assays evaluated the capacity of these antioxidants to sequester 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS.) and 1,1 diphenyl-2-picrylhydrazyl (DPPH.). A new colorimetric method to determine hydroxyl radical scavenging is also described. The biological tests use the eucaryotic cells of Saccharomyces cerevisiae treated with the antioxidants in the presence of the stressing agents apomorphine, hydrogen peroxide, and paraquat dichloride (methylviologen; 1,1'-dimethyl-4,4'-bipyridinium dichloride). The results in chemical systems showed that all of the antioxidants were able to significantly inhibit the oxidation of beta-carotene by hydroxyl free radicals. The assays in yeast showed that the antioxidant activity of the tested compounds depended on the stressing agent used and the mechanism of action of the antioxidant.
    Biochemical Pharmacology, 1994, 48(2):419-422.
    Propyl gallate as a hepatoprotector in vitro and in vivo.[Pubmed: 8053938]
    Recently, there has been renewed interest in Propyl gallate, a preservative in foods and fuels. This compound, which exhibits antimicrobial activity, has been found to be toxicologically safe after almost 30 years of evaluation.
    METHODS AND RESULTS:
    In the present study, we examined whether Propyl gallate is a hepatoprotective antioxidant, and investigated some of its bases of action vis-à-vis Trolox, a vitamin E analogue. In isolated rat hepatocytes, Propyl gallate prolonged substantially cell survival against oxyradicals generated with xanthine oxidase-hypoxanthine. The protection was dose dependent and excelled that of Trolox, mannitol, or ascorbate, each at or near its optimum level in the same system. In rats undergoing an 80-min partial hepatic ischemia, infusion of Propyl gallate at 20 mumol/kg body weight just before a 24-hr reperfusion salvaged the organ by 80.0 +/- 11.5%, an extent comparable to that with Trolox. Mechanistically, we found that Propyl gallate (a) protected hepatocytes against the cascade of oxyradicals produced by xanthine oxidase-hypoxanthine; (b) protected hepatocytes against superoxide radicals generated specifically by menadione; (c) protected the functionally important hepatic vascular endothelial cells more effectively than Trolox against xanthine oxidase-hypoxanthine, and (d) approximately halved the amount of lipid conjugated dienes (a more specific marker of oxyradical damage than malondialdehyde) formed in tissues after oxidant damage.
    CONCLUSIONS:
    Therefore, there are fundamental reasons why Propyl gallate is an effective antioxidant-based hepatoprotector, both in vitro and in vivo.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.7125 mL 23.5627 mL 47.1254 mL 94.2507 mL 117.8134 mL
    5 mM 0.9425 mL 4.7125 mL 9.4251 mL 18.8501 mL 23.5627 mL
    10 mM 0.4713 mL 2.3563 mL 4.7125 mL 9.4251 mL 11.7813 mL
    50 mM 0.0943 mL 0.4713 mL 0.9425 mL 1.885 mL 2.3563 mL
    100 mM 0.0471 mL 0.2356 mL 0.4713 mL 0.9425 mL 1.1781 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Leucodin ; Leucodin CFN96803 17946-87-1 C15H18O3 = 246.30 5mg QQ客服:2056216494
    甲氧醉椒素; Yangonin CFN92658 500-62-9 C15H14O4 = 258.3 20mg QQ客服:2056216494
    月腺大戟素E; Yuexiandajisu E CFN92875 866556-16-3 C20H30O5 = 350.4 5mg QQ客服:215959384
    Lancifolin C; Lancifolin C CFN00307 74048-71-8 C22H28O5 = 372.5 5mg QQ客服:215959384

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