瓜子金皂苷XXXI
Polygalasaponin XXXI
|
|
产品编号 |
CFN90728 |
| CAS编号 |
79103-90-5 |
| 分子式 = 分子量 |
C75H112O36 = 1589.67 |
| 产品纯度 |
>=98% |
| 物理属性 |
Powder |
| 化合物类型 |
Triterpenoids |
| 植物来源 |
The herbs of Polygala japonica Houtt. |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 瓜子金皂苷XXXI |
CFN90728 |
79103-90-5 |
1mg |
QQ客服：3257982914 |
| 瓜子金皂苷XXXI |
CFN90728 |
79103-90-5 |
5mg |
QQ客服：3257982914 |
| 瓜子金皂苷XXXI |
CFN90728 |
79103-90-5 |
10mg |
QQ客服：3257982914 |
| 瓜子金皂苷XXXI |
CFN90728 |
79103-90-5 |
20mg |
QQ客服：3257982914 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
University of Mysore (India)
VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
Centralised Purchases Unit (CPU), B.I.T.S (India)
Wroclaw Medical University (Poland)
Universiti Malaysia Pahang (Malaysia)
The Australian National University (Australia)
University of Toronto (Canada)
Heinrich-Heine-University Düsseldorf (Germany)
Martin Luther University of Halle-Wittenberg (Germany)
University of Maryland School of Medicine (USA)
Lodz University of Technology (Poland)
Nanjing University of Chinese Medicine (China)
Ateneo de Manila University (Philippines)
Sanford Burnham Prebys Medical Discovery Institute (USA)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Onjisaponin F(Polygalasaponin XXXI) acts non-competitively against cyclic AMP phosphodiesterase, like papaverine; it also exhibits a prolongation effect on hexobarbital sleeping time in mice. Intranasal vaccination with onjisaponin F(Polygalasaponin XXXI) can inhibit proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice. |
| Targets: |
cAMP |
| In vivo: |
| Acta Horticulturae, 2005 , 679 (679) :121-129. | | Intranasally and orally effective adjuvants from Chinese and Japanese medicinal herbs for nasal influenza vaccine[Reference: WebLink] | Active substances from hot water extracts from 267 different Chinese and Japanese medicinal herbs were screened for mucosal adjuvant activity with influenza HA vaccine in mice.
The extract from the root of Polygala tenuifolia was found to contain potent mucosal adjuvant activity.
METHODS AND RESULTS:
The active substances were purified and identified as onjisaponins A, E, F and G. Two inoculations of mice with onjisaponin F ((Polygalasaponin XXXI,1 μg) and influenza HA vaccine (1 μg) at 3 weeks intervals, significantly increased serum HI antibody and nasal anti-influenza virus IgA and IgG antibody titers after only 1 week over mice given HA vaccine alone after the secondary vaccination. Intranasal vaccination with onjisaponin F(Polygalasaponin XXXI) inhibited proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice. Onjisaponins also showed adjuvant effect for intranasal vaccination of diphtheria-pertussis-tetanus (DPT) vaccine.
CONCLUSIONS:
Traditional Japanese herbal (Kampo) formulation, Sho-seiryu-to (Xiao-Qing-Long-Tang in Chinese) showed oral adjuvant activity for nasally administered influenza vaccine. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
0.6291 mL |
3.1453 mL |
6.2906 mL |
12.5812 mL |
15.7265 mL |
| 5 mM |
0.1258 mL |
0.6291 mL |
1.2581 mL |
2.5162 mL |
3.1453 mL |
| 10 mM |
0.0629 mL |
0.3145 mL |
0.6291 mL |
1.2581 mL |
1.5727 mL |
| 50 mM |
0.0126 mL |
0.0629 mL |
0.1258 mL |
0.2516 mL |
0.3145 mL |
| 100 mM |
0.0063 mL |
0.0315 mL |
0.0629 mL |
0.1258 mL |
0.1573 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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