Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose

	产品编号	CFN90881
	CAS编号	205370-59-8
	分子式 = 分子量	C₄₂H₃₂O₂₁ = 872.7
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The herbs of Lindera strychnifolia
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	10mg	QQ客服：215959384
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	20mg	QQ客服：215959384
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	50mg	QQ客服：215959384
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	100mg	QQ客服：215959384

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Donald Danforth Plant Science Center (USA)

St. Jude Children Research Hospital (USA)

University of Canterbury (New Zealand)

Shanghai University of TCM (China)

University of Zurich (Switzerland)

University of Otago (New Zealand)

Sanford Burnham Prebys Medical Discovery Institute (USA)

University of Queensland (Australia)

Cancer Research Initatives Foundation(CARIF) (Malaysia)

Guangzhou Institutes of Biomedicine and Health (China)

Kyung Hee University (Korea)

Washington State University (USA)

Tokyo Woman's Christian University (Japan)

Shanghai Institute of Organic Chemistry (China)

More...

Description:

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.

In vivo:

J Ethnopharmacol. 2015 Apr 2;163:256-63.

Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.[Pubmed: 25620384 ]

METHODS AND RESULTS:
The Penthorum chinense extract possessed anti-hyperglycemic activities as shown by the decreased serum levels of glycosylated hemoglobulin A1C (HbA1c), triglyceride(TG), total cholesterol (TC), and low density lipoprotein-cholesterol (LDL-C), as well as increased serum levels of high density lipoprotein-cholesterol (HDL-C) and insulin. Penthorum chinense extract also improved the oral glucose tolerance test (OGTT) to a certain degree. Moreover, the OSTT study showed that in diabetic rats, the extract (600mg/kg) caused a significant hypoglycemic effect with a blood glucose reduction of 42% at 60min. To identify the active constituents, three polyphenols, pinocembrin-7-O-[4″,6″-hexahydroxydiphenoyl]-β-d-glucose (1), pinocembrin-7-O-[3″-O-galloyl-4″, 6″-hexahydroxydiphenoyl]-β- d-glucose (Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,2), and thonningianin A (3) were isolated from Penthorum chinense.
CONCLUSIONS:
Compounds 1-3 moderately inhibited α-amylase activity, with IC50 values of 0.14, 0.03, and 0.08μmol/ml, respectively.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
葡萄糖没食子鞣苷; beta-Glucogallin	CFN70245	13405-60-2	C₁₃H₁₆O₁₀ = 332.3	5mg	QQ客服：2159513211
1-O-没食子酰-6-O-肉桂酰葡萄糖; 1-O-galloyl-6-O-cinnamoylglucose	CFN95053	115746-69-5	C₂₂H₂₂O₁₁ = 462.4	5mg	QQ客服：215959384
2-肉桂酰-1-没食子酰葡萄糖; 2-Cinnamoyl-1-galloylglucose	CFN95098	56994-83-3	C₂₂H₂₂O₁₁ = 462.4	5mg	QQ客服：1457312923
香草酸葡萄糖酯; 1-O-Vanilloylglucose	CFN95663	68985-14-8	C₁₄H₁₈O₉ = 330.3	5mg	QQ客服：2159513211
1,2,3,4,6-五没食子酰葡萄糖; 1,2,3,4,6-O-Pentagalloylglucose	CFN90192	14937-32-7	C₄₁H₃₂O₂₆ = 940.68	20mg	QQ客服：3257982914
单宁酸; Tannic acid	CFN90501	1401-55-4	C₇₆H₅₂O₄₆ = 1701.2	20mg	QQ客服：1413575084
柯里拉京; Corilagin	CFN90176	23094-69-1	C₂₇H₂₂O₁₈ = 634.45	20mg	QQ客服：1457312923
诃子宁; Chebulanin	CFN92294	166833-80-3	C₂₇H₂₄O₁₉ = 652.5	5mg	QQ客服：2159513211
乔松苷；乔松素-7-O-β-D-葡萄糖苷; Pinocembroside	CFN95444	75829-43-5	C₂₁H₂₂O₉ = 418.4	20mg	QQ客服：2159513211
赶黄草苷B; Thonningianin B	CFN91481	271579-12-5	C₃₅H₃₀O₁₇ = 722.6	5mg	QQ客服：1413575084

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.1459 mL	5.7293 mL	11.4587 mL	22.9174 mL	28.6467 mL
5 mM	0.2292 mL	1.1459 mL	2.2917 mL	4.5835 mL	5.7293 mL
10 mM	0.1146 mL	0.5729 mL	1.1459 mL	2.2917 mL	2.8647 mL
50 mM	0.0229 mL	0.1146 mL	0.2292 mL	0.4583 mL	0.5729 mL
100 mM	0.0115 mL	0.0573 mL	0.1146 mL	0.2292 mL	0.2865 mL

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose

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