Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose

	产品编号	CFN90881
	CAS编号	205370-59-8
	分子式 = 分子量	C₄₂H₃₂O₂₁ = 872.7
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The herbs of Lindera strychnifolia
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	10mg	QQ客服：2056216494
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	20mg	QQ客服：2056216494
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	50mg	QQ客服：2056216494
Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose	CFN90881	205370-59-8	100mg	QQ客服：2056216494

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Martin Luther University of Halle-Wittenberg (Germany)

Kamphaengphet Rajabhat University (Thailand)

Kyoto University (Japan)

Griffith University (Australia)

Imperial College London (United Kingdom)

University of Bonn (Germany)

Sanford Burnham Prebys Medical Discovery Institute (USA)

Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)

University of Dicle (Turkey)

University of Padjajaran (Indonesia)

Sant Gadge Baba Amravati University (India)

Heinrich-Heine-University Düsseldorf (Germany)

Lund University (Sweden)

Univerzita Karlova v Praze (Czech Republic)

More...

Description:

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.

In vivo:

J Ethnopharmacol. 2015 Apr 2;163:256-63.

Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.[Pubmed: 25620384 ]

METHODS AND RESULTS:
The Penthorum chinense extract possessed anti-hyperglycemic activities as shown by the decreased serum levels of glycosylated hemoglobulin A1C (HbA1c), triglyceride(TG), total cholesterol (TC), and low density lipoprotein-cholesterol (LDL-C), as well as increased serum levels of high density lipoprotein-cholesterol (HDL-C) and insulin. Penthorum chinense extract also improved the oral glucose tolerance test (OGTT) to a certain degree. Moreover, the OSTT study showed that in diabetic rats, the extract (600mg/kg) caused a significant hypoglycemic effect with a blood glucose reduction of 42% at 60min. To identify the active constituents, three polyphenols, pinocembrin-7-O-[4″,6″-hexahydroxydiphenoyl]-β-d-glucose (1), pinocembrin-7-O-[3″-O-galloyl-4″, 6″-hexahydroxydiphenoyl]-β- d-glucose (Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,2), and thonningianin A (3) were isolated from Penthorum chinense.
CONCLUSIONS:
Compounds 1-3 moderately inhibited α-amylase activity, with IC50 values of 0.14, 0.03, and 0.08μmol/ml, respectively.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
叶下珠鞣质C; Phyllanthusiin C	CFN95260	142674-52-0	C₄₀H₃₀O₂₆ = 926.7	5mg	QQ客服：215959384
诃子鞣酸; Chebulagic acid	CFN92295	23094-71-5	C₄₁H₃₀O₂₇ = 954.7	5mg	QQ客服：1413575084
诃子林鞣酸; Chebulinic acid	CFN92296	18942-26-2	C₄₁H₃₂O₂₇ = 956.7	20mg	QQ客服：2056216494
新诃黎勒鞣花酸甲酯; Methyl neochebulinate	CFN95201	1236310-34-1	C₄₂H₃₆O₂₈ = 988.7	5mg	QQ客服：2056216494
特里马素I; Tellimagrandin I	CFN95810	79786-08-6	C₃₄H₂₆O₂₂ = 786.6	10mg	QQ客服：1457312923
特里马素II; Tellimagrandin II	CFN95792	81571-72-4	C₄₁H₃₀O₂₆ = 938.7	10mg	QQ客服：2056216494
木麻黄鞣亭; Casuarictin	CFN95843	79786-00-8	C₄₁H₂₈O₂₆ = 936.7	5mg	QQ客服：215959384
月见草素 B; Oenothein B	CFN91651	104987-36-2	C₆₈H₄₈O₄₄ = 1569.1	5mg	QQ客服：2159513211
1,2,3,6-四-O-没食子酰-β-D-葡萄糖; 1,2,3,6-Tetragalloylglucose	CFN00447	79886-50-3	C₃₄H₂₈O₂₂ = 788.57	10mg	QQ客服：3257982914
1,3,4,6-四没食子酰葡萄糖; 1,3,4,6-Tetragalloylglucose	CFN95425	26922-99-6	C₃₄H₂₈O₂₂ = 788.6	10mg	QQ客服：1413575084

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.1459 mL	5.7293 mL	11.4587 mL	22.9174 mL	28.6467 mL
5 mM	0.2292 mL	1.1459 mL	2.2917 mL	4.5835 mL	5.7293 mL
10 mM	0.1146 mL	0.5729 mL	1.1459 mL	2.2917 mL	2.8647 mL
50 mM	0.0229 mL	0.1146 mL	0.2292 mL	0.4583 mL	0.5729 mL
100 mM	0.0115 mL	0.0573 mL	0.1146 mL	0.2292 mL	0.2865 mL

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-β-D-glucose

Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose

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