巴利森苷A

Parishin A

	产品编号	CFN93112
	CAS编号	62499-28-9
	分子式 = 分子量	C₄₅H₅₆O₂₅ = 996.9
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Phenols
	植物来源	The rhizomes of Gastrodia elata
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
巴利森苷A	CFN93112	62499-28-9	10mg	QQ客服：1413575084
巴利森苷A	CFN93112	62499-28-9	20mg	QQ客服：1413575084
巴利森苷A	CFN93112	62499-28-9	50mg	QQ客服：1413575084
巴利森苷A	CFN93112	62499-28-9	100mg	QQ客服：1413575084

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

MTT Agrifood Research Finland (Finland)

Chiang Mai University (Thailand)

Monash University Malaysia (Malaysia)

University of Hawaii Cancer Center (USA)

Universiti Sains Malaysia (Malaysia)

Agricultural Research Organization (ARO) (Israel)

Universidad de Ciencias y Artes de Chiapas (Mexico)

Northeast Normal University Changchun (China)

Universiti Putra Malaysia(UPM) (Malaysia)

Massachusetts General Hospital (USA)

Medical University of Gdansk (Poland)

Siksha O Anusandhan University (India)

University of Hull (United Kingdom)

Biotech R&D Institute (USA)

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Description:

Parishin A has good neuroprotective effects against brain disorders.

In vitro:

Oxid Med Cell Longev . 2016;2016:4074690.

Parishin from Gastrodia elata Extends the Lifespan of Yeast via Regulation of Sir2/Uth1/TOR Signaling Pathway[Pubmed: 27429709]

Abstract Parishin is a phenolic glucoside isolated from Gastrodia elata, which is an important traditional Chinese medicine; this glucoside significantly extended the replicative lifespan of K6001 yeast at 3, 10, and 30 μM. To clarify its mechanism of action, assessment of oxidative stress resistance, superoxide dismutase (SOD) activity, malondialdehyde (MDA), and reactive oxygen species (ROS) assays, replicative lifespans of sod1, sod2, uth1, and skn7 yeast mutants, and real-time quantitative PCR (RT-PCR) analysis were conducted. The significant increase of cell survival rate in oxidative stress condition was observed in parishin-treated groups. Silent information regulator 2 (Sir2) gene expression and SOD activity were significantly increased after treating parishin in normal condition. Meanwhile, the levels of ROS and MDA in yeast were significantly decreased. The replicative lifespans of sod1, sod2, uth1, and skn7 mutants of K6001 yeast were not affected by parishin. We also found that parishin could decrease the gene expression of TORC1, ribosomal protein S26A (RPS26A), and ribosomal protein L9A (RPL9A) in the target of rapamycin (TOR) signaling pathway. Gene expression levels of RPS26A and RPL9A in uth1, as well as in uth1, sir2 double mutants, were significantly lower than those of the control group. Besides, TORC1 gene expression in uth1 mutant of K6001 yeast was inhibited significantly. These results suggested that parishin exhibited antiaging effects via regulation of Sir2/Uth1/TOR signaling pathway.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
巴利森苷B; Parishin B	CFN93113	174972-79-3	C₃₂H₄₀O₁₉ = 728.7	20mg	QQ客服：3257982914
巴利森苷C; Parishin C	CFN93114	174972-80-6	C₃₂H₄₀O₁₉ = 728.7	20mg	QQ客服：1413575084
巴利森苷A; Parishin A	CFN93112	62499-28-9	C₄₅H₅₆O₂₅ = 996.9	20mg	QQ客服：1457312923
1,4-二[4-(葡萄糖氧)苄基]-2-异丁基苹果酸酯; Militarine	CFN90409	58139-23-4	C₃₄H₄₆O₁₇ = 726.73	20mg	QQ客服：215959384
Dactylorhin A; Dactylorhin A	CFN95032	256459-34-4	C₄₀H₅₆O₂₂ = 888.9	20mg	QQ客服：215959384
Gymnoside III; Gymnoside III	CFN95033	899430-03-6	C₄₂H₅₈O₂₃ = 930.9	10mg	QQ客服：1413575084
4-(葡糖糖氧基)-肉桂酸葡萄糖氧基苄酯; Shancigusin I	CFN95061	1435488-35-9	C₂₈H₃₄O₁₄ = 594.6	5mg	QQ客服：2159513211
Bletilloside A; Bletilloside A	CFN91183	2292159-89-6	C₂₉H₃₆O₁₅ = 624.6	5mg	QQ客服：3257982914
3-甲氧基-4-(葡糖糖氧基)-肉桂酸葡萄糖氧基苄酯; 3-Methoxyshancigusin I	CFN95062	N/A	C₂₉H₃₆O₁₅ = 624.6	5mg	QQ客服：3257982914
水杨酸; Salicylic acid	CFN93274	69-72-7	C₇H₆O₃ = 138.12	20mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.0031 mL	5.0155 mL	10.0311 mL	20.0622 mL	25.0777 mL
5 mM	0.2006 mL	1.0031 mL	2.0062 mL	4.0124 mL	5.0155 mL
10 mM	0.1003 mL	0.5016 mL	1.0031 mL	2.0062 mL	2.5078 mL
50 mM	0.0201 mL	0.1003 mL	0.2006 mL	0.4012 mL	0.5016 mL
100 mM	0.01 mL	0.0502 mL	0.1003 mL	0.2006 mL	0.2508 mL