神经酸
Nervonic acid
|
|
产品编号 |
CFN93241 |
| CAS编号 |
506-37-6 |
| 分子式 = 分子量 |
C24H46O2 = 366.63 |
| 产品纯度 |
>=98% |
| 物理属性 |
Powder |
| 化合物类型 |
Miscellaneous |
| 植物来源 |
The seeds of Acer truncatum Bunge |
| ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用 |
|
| 产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
| 神经酸 |
CFN93241 |
506-37-6 |
1mg |
QQ客服：3004468088 |
| 神经酸 |
CFN93241 |
506-37-6 |
5mg |
QQ客服：3004468088 |
| 神经酸 |
CFN93241 |
506-37-6 |
10mg |
QQ客服：3004468088 |
| 神经酸 |
CFN93241 |
506-37-6 |
20mg |
QQ客服：3004468088 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
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Pennsylvania State University (USA)
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Universidad Miguel Hernández (Spain)
Sanford Burnham Medical Research Institute (USA)
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University of Illinois (USA)
Utrecht University (Netherlands)
Korea Intitute of Science and Technology (KIST) (Korea)
Leibniz Institute of Plant Biochemistry (Germany)
Ateneo de Manila University (Philippines)
University of Limpopo (South Africa)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
| Description: |
Nervonic acid improves learning memory ability in normal mice and mice with experimental memory impairment. Nervonic acid can inhibit DNA polymerase beta and HIV-1 reverse transcriptase.
|
| Targets: |
HIV |
| In vivo: |
| The Experimental Biology. 2004. | | Nervonic Acid improves learning memory ability in normal mice and mice with experimental memory impairment[Reference: WebLink] | Nervonic acid (NA), a monounsaturated fatty acid (C24:1), is a component of membranes of the nervous system.
METHODS AND RESULTS:
We employed platform step-down (PSD) and water-maze swim (WMS) technologies and examined in this study the effects of NA in improving learning memory in 3 animal models: normal mice and mice with memory impairment. NA was given to mice at a dose of 12.3, 24.5, or 49.0 mg/kg by gavage. (1) In normal mice, 22 days of oral NA supplementation reduced the number of PSD mistakes (p=0.003) and extended the PSD latency (p=0.040). (2) After 30 days of oral NA or placebo, mice were given scopolamine (2 mg/kg, i.p.) at Day 30, to induce learning memory impairment. The number of PSD mistakes was reduced with NA (p<0.001). (3) Mice received oral NA for 35 days and i.p. scopolamine for 7 days (the 28th to 34th day). The number of dead-end mistakes in WMS test was reduced in NA-treated mice (p=0.025). A 90-day test revealed that oral NA caused increases in serum ALT and total cholesterol and decreases in blood glucose in rats.
CONCLUSIONS:
These results indicate that oral NA supplementation is effective on enhancing memory in both normal mice and mice with experimental memory impairment, but its toxicity may prohibit its use. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.7275 mL |
13.6377 mL |
27.2755 mL |
54.5509 mL |
68.1886 mL |
| 5 mM |
0.5455 mL |
2.7275 mL |
5.4551 mL |
10.9102 mL |
13.6377 mL |
| 10 mM |
0.2728 mL |
1.3638 mL |
2.7275 mL |
5.4551 mL |
6.8189 mL |
| 50 mM |
0.0546 mL |
0.2728 mL |
0.5455 mL |
1.091 mL |
1.3638 mL |
| 100 mM |
0.0273 mL |
0.1364 mL |
0.2728 mL |
0.5455 mL |
0.6819 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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