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  • Myzodendrone

    Myzodendrone

    Myzodendrone
    产品编号 CFN96954
    CAS编号 101705-37-7
    分子式 = 分子量 C16H22O8 = 342.34
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The flowering stems of Vitex agnus-castus.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Myzodendrone CFN96954 101705-37-7 1mg QQ客服:2056216494
    Myzodendrone CFN96954 101705-37-7 5mg QQ客服:2056216494
    Myzodendrone CFN96954 101705-37-7 10mg QQ客服:2056216494
    Myzodendrone CFN96954 101705-37-7 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • University of Liège (Belgium)
  • Copenhagen University (Denmark)
  • University of the Basque Country (Spain)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Seoul National University (Korea)
  • Calcutta University (India)
  • Istanbul University (Turkey)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Funda??o Universitária de Desenvolvimento (Brazil)
  • University of Illinois at Chicago (USA)
  • University of Queensland (Australia)
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Chiang Mai University (Thailand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Curr Issues Mol Biol.2022, 44(10):5106-5116.
  • Molecules.2023, 28(10):4121.
  • Kasetsart University2022, ethesis.1144.
  • Front Immunol.2018, 9:2655
  • J Pharm Biomed Anal.2021, 196:113931.
  • Phytother Res.2018, 32(12):2551-2559
  • Pharmaceuticals (Basel).2021, 14(7):633.
  • Heliyon2020, 6(6):e04337.
  • Evid Based Complement Alternat Med.2020, 2020:8582318.
  • Mie University2019, 10076.
  • Enzyme Microb Technol.2019, 122:64-73
  • Neurotox Res.2020, 38(1):163-174.
  • RSC Adv.2018, 32621-32636
  • Front Microbiol.2023, 14:921653.
  • Toxicol In Vitro.2023, 86:105521.
  • Molecules.2023, 28(13):4971.
  • Food Bioscience2023, 56:103311.
  • Food Chem.2017, 221:1135-1144
  • Food Chem X.2024, 21:101208.
  • BioRxiv-The Preprint server for biology2023, 586957.
  • Molecules.2017, 22(2)
  • Ulm University Medical Center2020, doi: 10.18725.
  • Appl. Sci.2020, 10(5),1713.
  • ...
  • 生物活性
    Description: Myzodendrone is a highly effective as free radical scavenger.
    In vitro:
    Phytother Res. 2005 Dec;19(12):1043-7.
    Antioxidant and free radical scavenging activities of Misodendrum punctulatum, myzodendrone and structurally related phenols.[Pubmed: 16372370 ]

    METHODS AND RESULTS:
    The peroxyl radical scavenging activity of a dry methanol extract of Misodendrum punctulatum was determined by means of luminol-enhanced chemiluminescence assay, allowing to calculate the total reactive antioxidant potential (TRAP) index equal to 239 +/- 26 microm, expressed in Trolox equivalents. The flavan-3-ol catechin (1) and the phenylbutanone derivative Myzodendrone (2) were identified through assay-guided fractionation as active metabolites present in the extract, and their structures were elucidated by chemical and spectroscopic analysis. Three other structurally related synthetic phenols, dehydrozingerone (3), zingerone (4) and Myzodendrone aglycone (5), were also analysed using this method.
    CONCLUSIONS:
    Compounds 1 and 2 were highly effective as free radical scavengers (TRAP = 1257 microm and 1018 microm, respectively) when compared with Trolox (TRAP = 144 microm), used as a standard. Compounds 3 and 5 were also active showing TRAP values of 229 microm and 219 microm, respectively, similarly to that observed for the dry extract. On the other hand, 4 was inactive. Catechin (1) also reduced the production of thiobarbituric acid reactive substances (TBARS) in rat liver homogenates, with IC50 = 26 microg/mL, superior to that obtained for Trolox, IC50 = 73 microg/mL. Compounds 2 and 5 showed IC50 values > 1000 microg/mL, while no activity could be observed for 3, 4, or the extract.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9211 mL 14.6054 mL 29.2107 mL 58.4215 mL 73.0268 mL
    5 mM 0.5842 mL 2.9211 mL 5.8421 mL 11.6843 mL 14.6054 mL
    10 mM 0.2921 mL 1.4605 mL 2.9211 mL 5.8421 mL 7.3027 mL
    50 mM 0.0584 mL 0.2921 mL 0.5842 mL 1.1684 mL 1.4605 mL
    100 mM 0.0292 mL 0.1461 mL 0.2921 mL 0.5842 mL 0.7303 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    FD-838 ; FD-838 CFN96970 110341-78-1 C22H21NO7 = 411.41 5mg QQ客服:2056216494
    11beta,13-二氢山莴苣素; 11beta,13-Dihydrolactucin CFN95433 83117-63-9 C15H18O5 = 278.3 10mg QQ客服:1457312923
    培美曲塞二钠; Pemetrexed disodium CFN90017 150399-23-8 C20H19N5Na2O6 = 471.37 5mg QQ客服:2159513211
    鸦胆醇; Bruceantinol CFN89336 53729-52-5 C30H38O13 = 606.62 5mg QQ客服:1413575084

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