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  • Myzodendrone

    Myzodendrone

    Myzodendrone
    产品编号 CFN96954
    CAS编号 101705-37-7
    分子式 = 分子量 C16H22O8 = 342.34
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The flowering stems of Vitex agnus-castus.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Myzodendrone CFN96954 101705-37-7 1mg QQ客服:3257982914
    Myzodendrone CFN96954 101705-37-7 5mg QQ客服:3257982914
    Myzodendrone CFN96954 101705-37-7 10mg QQ客服:3257982914
    Myzodendrone CFN96954 101705-37-7 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Brasilia (Brazil)
  • Korea Food Research Institute(KFRI) (Korea)
  • University of Medicine and Pharmacy (Romania)
  • Lodz University of Technology (Poland)
  • MTT Agrifood Research Finland (Finland)
  • University of Minnesota (USA)
  • Imperial College London (United Kingdom)
  • Stanford University (USA)
  • University of Hawaii Cancer Center (USA)
  • Universidade de Franca (Brazil)
  • Siksha O Anusandhan University (India)
  • Charles University in Prague (Czech Republic)
  • Monash University Sunway Campus (Malaysia)
  • VIT University (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Translational Neuroscience2024, 15:20220339
  • J. Pharm. Biomed. Anal.2024, 245:116193.
  • Nat Prod Commun.2017, 12(5):771-778
  • Plant Sci.2021, 313:111069.
  • Phytomedicine.2023, 114:154813.
  • Molecules2022, 27(12):3903.
  • J Holistic Integrative Pharm.2023, 4(1):14-28
  • Chemistry of Plant Materials.2019, 129-136
  • J of Applied Biological Chem.2020, 63(2):147-152
  • Saudi Pharm J.2019, 27(1):145-153
  • Int J Mol Sci.2023, 24(17):13230.
  • The Japan Society for Analytical Chemistry2017, 613-617
  • Int J Oncol.2019, 55(1):320-330
  • Clin Transl Oncol.2019, 10.1007
  • J Korean Soc Food Sci Nutr2020, doi: 10.3746.
  • Planta Med.2018, 84(6-07):465-474
  • Plant Pathology2022, 10.1111:ppa.13651.
  • J AOAC Int.2023, 106(1):56-64.
  • BMC Plant Biol.2022, 22(1):128.
  • J Appl Biol Chem2021, 64(3):245-251.
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • Int J Mol Sci.2022, 23(21):13112.
  • Front Immunol.2020, 11:598556.
  • ...
  • 生物活性
    Description: Myzodendrone is a highly effective as free radical scavenger.
    In vitro:
    Phytother Res. 2005 Dec;19(12):1043-7.
    Antioxidant and free radical scavenging activities of Misodendrum punctulatum, myzodendrone and structurally related phenols.[Pubmed: 16372370 ]

    METHODS AND RESULTS:
    The peroxyl radical scavenging activity of a dry methanol extract of Misodendrum punctulatum was determined by means of luminol-enhanced chemiluminescence assay, allowing to calculate the total reactive antioxidant potential (TRAP) index equal to 239 +/- 26 microm, expressed in Trolox equivalents. The flavan-3-ol catechin (1) and the phenylbutanone derivative Myzodendrone (2) were identified through assay-guided fractionation as active metabolites present in the extract, and their structures were elucidated by chemical and spectroscopic analysis. Three other structurally related synthetic phenols, dehydrozingerone (3), zingerone (4) and Myzodendrone aglycone (5), were also analysed using this method.
    CONCLUSIONS:
    Compounds 1 and 2 were highly effective as free radical scavengers (TRAP = 1257 microm and 1018 microm, respectively) when compared with Trolox (TRAP = 144 microm), used as a standard. Compounds 3 and 5 were also active showing TRAP values of 229 microm and 219 microm, respectively, similarly to that observed for the dry extract. On the other hand, 4 was inactive. Catechin (1) also reduced the production of thiobarbituric acid reactive substances (TBARS) in rat liver homogenates, with IC50 = 26 microg/mL, superior to that obtained for Trolox, IC50 = 73 microg/mL. Compounds 2 and 5 showed IC50 values > 1000 microg/mL, while no activity could be observed for 3, 4, or the extract.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9211 mL 14.6054 mL 29.2107 mL 58.4215 mL 73.0268 mL
    5 mM 0.5842 mL 2.9211 mL 5.8421 mL 11.6843 mL 14.6054 mL
    10 mM 0.2921 mL 1.4605 mL 2.9211 mL 5.8421 mL 7.3027 mL
    50 mM 0.0584 mL 0.2921 mL 0.5842 mL 1.1684 mL 1.4605 mL
    100 mM 0.0292 mL 0.1461 mL 0.2921 mL 0.5842 mL 0.7303 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    次皂甙元CP6; Prosapogenin CP6 CFN90392 72629-76-6 C46H74O16 = 882.50 5mg QQ客服:215959384
    双穿心莲内酯 A; Bisandrographolide A CFN97814 160498-00-0 C40H56O8 = 664.88 5mg QQ客服:1413575084
    1-甲氧基菜豆素; 1-Methoxyphaseollidin CFN96878 65428-13-9 C21H22O5 = 354.40 5mg QQ客服:2159513211
    酮基哈共醇; Ketohakonanol CFN89135 18004-20-1 C29H48O2 = 428.70 5mg QQ客服:3257982914

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