Info: Read More
  • 中药标准品生产商,产品定制服务
  • L-缬氨酸

    L-Valine

    L-缬氨酸
    产品编号 CFN94831
    CAS编号 72-18-4
    分子式 = 分子量 C5H11NO2 = 117.1
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The cultures of Corynebacterium glutamicum.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    L-缬氨酸 CFN94831 72-18-4 10mg QQ客服:215959384
    L-缬氨酸 CFN94831 72-18-4 20mg QQ客服:215959384
    L-缬氨酸 CFN94831 72-18-4 50mg QQ客服:215959384
    L-缬氨酸 CFN94831 72-18-4 100mg QQ客服:215959384
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universidade de Franca (Brazil)
  • National Cancer Institute (USA)
  • Mahatma Gandhi University (India)
  • Kyung Hee University (Korea)
  • University of Hawaii Cancer Center (USA)
  • Instytut Nawozów Sztucznych w Pu?awach (Poland)
  • University of Liège (Belgium)
  • Donald Danforth Plant Science Center (USA)
  • Universidad Veracuzana (Mexico)
  • Julius Kühn-Institut (Germany)
  • Instituto Politécnico de Bragan?a (Portugal)
  • S.N.D.T. Women's University (India)
  • University of East Anglia (United Kingdom)
  • Uniwersytet Gdański (Poland)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J. of Agricultural Science2015, 1916-9760
  • Pharmacol Rep.2018, 70(6):1195-1201
  • Virulence.2018, 9(1):588-603
  • Nutrients.2018, 10(12)
  • Molecules.2021, 26(4):816.
  • Pharmacia2024, 71:1-9.
  • Biol Pharm Bull.2020, 43(10):1534-1541.
  • Inflammation.2021, doi: 10.1007
  • Plant Sci.2020, 301:110656.
  • JLiquid Chromatography & Related Tech.2021, 10826076.
  • Oxid Med Cell Longev.2020, 2020:8887251.
  • EXCLI J.2023, 22:482-498.
  • Pharmacol Rep.2017, 69(6):1224-1231
  • Molecules2022, 27(9):2827.
  • Molecular Simulation2023, 49(8):799-815.
  • Wageningen University & Research2018, January 2018
  • Cell Mol Biol (Noisy-le-grand).2023, 69(15):167-173.
  • Internoational J of Toxicology2020, 10.1177.
  • Molecules.2021, 26(4):1084.
  • Drug Des Devel Ther.2020, 14:5189-5204.
  • J Microbiol Biotechnol.2023, 33(10):1317-1328.
  • Molecules.2019, 24(16):E2985
  • Natural Product Sciences2023, 29(4):276-280.
  • ...
  • 生物活性
    Description: L-Valine is an essential amino acid for the human body. L-Valine and L-isoleucine could be used in the supplements of low-protein corn and soybean meal all-vegetable diets for broilers.
    In vitro:
    Appl Environ Microbiol. 2007 Apr;73(7):2079-84.
    L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum.[Pubmed: 17293513 ]

    METHODS AND RESULTS:
    Corynebacterium glutamicum was engineered for the production of L-valine from glucose by deletion of the aceE gene encoding the E1p enzyme of the pyruvate dehydrogenase complex and additional overexpression of the ilvBNCE genes encoding the L-valine biosynthetic enzymes acetohydroxyacid synthase, isomeroreductase, and transaminase B. In the absence of cellular growth, C. glutamicum DeltaaceE showed a relatively high intracellular concentration of pyruvate (25.9 mM) and produced significant amounts of pyruvate, L-alanine, and L-valine from glucose as the sole carbon source. Lactate or acetate was not formed. Plasmid-bound overexpression of ilvBNCE in C. glutamicum DeltaaceE resulted in an approximately 10-fold-lower intracellular pyruvate concentration (2.3 mM) and a shift of the extracellular product pattern from pyruvate and L-alanine towards L-valine.
    CONCLUSIONS:
    In fed-batch fermentations at high cell densities and an excess of glucose, C. glutamicum DeltaaceE(pJC4ilvBNCE) produced up to 210 mM L-valine with a volumetric productivity of 10.0 mM h(-1) (1.17 g l(-1) h(-1)) and a maximum yield of about 0.6 mol per mol (0.4 g per g) of glucose.
    Biotechnol Bioeng. 2005 Aug 5;91(3):356-68.
    Application of model discriminating experimental design for modeling and development of a fermentative fed-batch L-valine production process.[Pubmed: 15984033]
    A model discriminating experimental design approach for fed-batch processes has been developed and applied to the fermentative production of L-Valine by a genetically modified Corynebacterium glutamicum strain possessing multiple auxotrophies as an example.
    METHODS AND RESULTS:
    Being faced with the typical situation of uncertain model information based on preliminary experiments, model discriminating design was successfully applied to improve discrimination between five competing models. Within the same modeling and experimental design framework, also the planning of an optimized production process with respect to the total volumetric productivity is shown. Simulation results were experimentally affirmed, yielding an increased total volumetric productivity of 6.2 mM L-Valine per hour.
    CONCLUSIONS:
    However, also so far unknown metabolic mechanisms were observed in the optimized process, underlining the importance of process optimization during modeling to avoid problems of extreme extrapolation of model predictions during the final process optimization.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 8.5397 mL 42.6985 mL 85.3971 mL 170.7942 mL 213.4927 mL
    5 mM 1.7079 mL 8.5397 mL 17.0794 mL 34.1588 mL 42.6985 mL
    10 mM 0.854 mL 4.2699 mL 8.5397 mL 17.0794 mL 21.3493 mL
    50 mM 0.1708 mL 0.854 mL 1.7079 mL 3.4159 mL 4.2699 mL
    100 mM 0.0854 mL 0.427 mL 0.854 mL 1.7079 mL 2.1349 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    原七叶皂苷元; Protoescigenin CFN70307 20853-07-0 C30H50O6 = 506.7 5mg QQ客服:2056216494
    TGX-221; TGX-221 CFN60188 663619-89-4 C21H24N4O2 = 364.44 5mg QQ客服:1457312923
    Officinaruminane B; Officinaruminane B CFN92687 1246282-67-6 C29H36O = 400.6 5mg QQ客服:3257982914
    山莴苣素; Lactucin CFN91605 1891-29-8 C15H16O5 = 276.28 5mg QQ客服:1413575084

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产