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  • 异鼠李素 3-O-洋槐糖苷

    Isorhamnetin 3-robinobioside

    异鼠李素 3-O-洋槐糖苷
    产品编号 CFN93057
    CAS编号 53584-69-3
    分子式 = 分子量 C28H32O16 = 624.54
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Typha angustifolia L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    异鼠李素 3-O-洋槐糖苷 CFN93057 53584-69-3 1mg QQ客服:1457312923
    异鼠李素 3-O-洋槐糖苷 CFN93057 53584-69-3 5mg QQ客服:1457312923
    异鼠李素 3-O-洋槐糖苷 CFN93057 53584-69-3 10mg QQ客服:1457312923
    异鼠李素 3-O-洋槐糖苷 CFN93057 53584-69-3 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules.2019, 24(6):E1155
  • Front Pharmacol.2020, 11:251.
  • Applied Biological Chem. 2020, 26(63).
  • Korean J Acupunct2020, 37:104-121
  • Antioxidants (Basel).2023, 12(1):189.
  • Bioorg Chem.2024, 145:107182.
  • J Pharm Biomed Anal.2022, 207:114398.
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  • Cells. 2023, 12(15):1934.
  • Neurochem Res.2021, s11064-021-03449-0
  • Heliyon.2022, e12337.
  • J Hematol Oncol.2018, 11(1):112
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • J Pharmaceut Biomed2020, 182:113110
  • Asian J Beauty Cosmetol2020, 18(3): 265-272.
  • Bio-protocol2018, 9(14):e3301
  • LWT2021, 138:110630.
  • J Pharm Biomed Anal.2024, 241:115990.
  • Trop J Nat Prod Res, February2023, 7(2):2371-2381
  • Toxicol Rep.2021, 8:1131-1142.
  • ...
  • 生物活性
    Description: Isorhamnetin 3-O-robinobioside has a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562.
    In vitro:
    BMC Complement Altern Med. 2012 Aug 22;12:135.
    Isorhamnetin 3-O-robinobioside from Nitraria retusa leaves enhance antioxidant and antigenotoxic activity in human chronic myelogenous leukemia cell line K562.[Pubmed: 22913434]
    In this report, the isorhamnetin 3-o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, were evaluated for their ability to induce antioxidant and antigenotoxic effects in human chronic myelogenous leukemia cell line.
    METHODS AND RESULTS:
    Nitraria retusa products properties were carried out by firstly evaluating their effects against lipid peroxidation induced by H2O2, using the thiobarbituric acid reactive substances species (TBARS) assay, and proceeding to the assay of cellular antioxidant activity, then doing the comet assay. The isorhamnetin 3-o-robinobioside(Isorhamnetin 3-robinobioside) showed a protective effect against lipid peroxidation induced by H2O2. The same natural compound and ethyl acetate extract inhibited oxidation induced by 2,2'-azobis (2-amidinopropane) dihydrochloride in human chronic myelogenous leukemia cells with respectively 50% inhibitory concentration values of 0.225 mg/ml and 0.31 mg/ml, reflecting a significant antioxidant potential. The same two products inhibited the genotoxicity induced by hydroxyl radicals in the same human cell line (by 77.77% at a concentration of 800 μg/ml and by 80.55% at a concentration of 1000 μg/ml respectively).
    CONCLUSIONS:
    The isorhamnetin 3- o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, have a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562. CONCLUSIONS: The isorhamnetin 3- o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, have a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6012 mL 8.0059 mL 16.0118 mL 32.0236 mL 40.0295 mL
    5 mM 0.3202 mL 1.6012 mL 3.2024 mL 6.4047 mL 8.0059 mL
    10 mM 0.1601 mL 0.8006 mL 1.6012 mL 3.2024 mL 4.0029 mL
    50 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6405 mL 0.8006 mL
    100 mM 0.016 mL 0.0801 mL 0.1601 mL 0.3202 mL 0.4003 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Laurycolactone A; Laurycolactone A CFN92130 85643-76-1 C18H22O5 = 318.4 5mg QQ客服:1457312923
    10-O-[(E)-3,4-二甲氧基肉桂酰)梓醇; 10-O-[(E)-3,4-Dimethoxycinnamoyl]-catalpol CFN91676 834155-36-1 C26H32O13 = 552.5 5mg QQ客服:1457312923
    一枝蒿酮酸; Rupestonic acid CFN94066 83161-56-2 C15H20O3 = 248.32 5mg QQ客服:215959384
    RA-V; RA-V CFN92605 64725-24-2 C40H48N6O9 = 756.9 5mg QQ客服:215959384

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