异鼠李素 3-O-洋槐糖苷

Isorhamnetin 3-robinobioside

	产品编号	CFN93057
	CAS编号	53584-69-3
	分子式 = 分子量	C₂₈H₃₂O₁₆ = 624.54
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Flavonoids
	植物来源	The herbs of Typha angustifolia L.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
异鼠李素 3-O-洋槐糖苷	CFN93057	53584-69-3	1mg	QQ客服：2056216494
异鼠李素 3-O-洋槐糖苷	CFN93057	53584-69-3	5mg	QQ客服：2056216494
异鼠李素 3-O-洋槐糖苷	CFN93057	53584-69-3	10mg	QQ客服：2056216494
异鼠李素 3-O-洋槐糖苷	CFN93057	53584-69-3	20mg	QQ客服：2056216494

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Kamphaengphet Rajabhat University (Thailand)

National Chung Hsing University (Taiwan)

Washington State University (USA)

University of Hull (United Kingdom)

Osmania University (India)

University of Medicine and Pharmacy (Romania)

University of Padjajaran (Indonesia)

University of Mysore (India)

Seoul National University of Science and Technology (Korea)

Medical University of Gdansk (Poland)

University of Indonesia (Indonesia)

Research Unit Molecular Epigenetics (MEG) (Germany)

Leibniz-Institut für Pflanzenbiochemie (IPB) (Germany)

Gyeongsang National University (Korea)

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Description:

Isorhamnetin 3-O-robinobioside has a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562.

In vitro:

BMC Complement Altern Med. 2012 Aug 22;12:135.

Isorhamnetin 3-O-robinobioside from Nitraria retusa leaves enhance antioxidant and antigenotoxic activity in human chronic myelogenous leukemia cell line K562.[Pubmed: 22913434]

In this report, the isorhamnetin 3-o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, were evaluated for their ability to induce antioxidant and antigenotoxic effects in human chronic myelogenous leukemia cell line.
METHODS AND RESULTS:
Nitraria retusa products properties were carried out by firstly evaluating their effects against lipid peroxidation induced by H2O2, using the thiobarbituric acid reactive substances species (TBARS) assay, and proceeding to the assay of cellular antioxidant activity, then doing the comet assay. The isorhamnetin 3-o-robinobioside(Isorhamnetin 3-robinobioside) showed a protective effect against lipid peroxidation induced by H2O2. The same natural compound and ethyl acetate extract inhibited oxidation induced by 2,2'-azobis (2-amidinopropane) dihydrochloride in human chronic myelogenous leukemia cells with respectively 50% inhibitory concentration values of 0.225 mg/ml and 0.31 mg/ml, reflecting a significant antioxidant potential. The same two products inhibited the genotoxicity induced by hydroxyl radicals in the same human cell line (by 77.77% at a concentration of 800 μg/ml and by 80.55% at a concentration of 1000 μg/ml respectively).
CONCLUSIONS:
The isorhamnetin 3- o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, have a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562. CONCLUSIONS: The isorhamnetin 3- o-robinobioside and its original extract, the ethyl acetate extract, from Nitraria retusa leaves, have a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
4-[(3R,5R)-3,5-二羟基-7-(4-羟基苯基)庚基]-1,2-苯二酚 ; 3,5-Dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane	CFN96858	408324-00-5	C₁₉H₂₄O₅ = 332.39	5mg	QQ客服：215959384
黄独素C; Diosbulbin C	CFN98015	20086-07-1	C₁₉H₂₂O₇ = 362.4	5mg	QQ客服：3257982914
苦杏碱醇A; Amaronol A	CFN98225	226560-96-9	C₁₅H₁₂O₈ = 320.3	5mg	QQ客服：2056216494
5,3'-二羟基-6,7,4',5'-四甲氧基黄酮; 3',5-Dihydroxy-4',5',6,7-tetramethoxyflavone	CFN99214	111537-41-8	C₁₉H₁₈O₈ = 374.4	5mg	QQ客服：3257982914

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.6012 mL	8.0059 mL	16.0118 mL	32.0236 mL	40.0295 mL
5 mM	0.3202 mL	1.6012 mL	3.2024 mL	6.4047 mL	8.0059 mL
10 mM	0.1601 mL	0.8006 mL	1.6012 mL	3.2024 mL	4.0029 mL
50 mM	0.032 mL	0.1601 mL	0.3202 mL	0.6405 mL	0.8006 mL
100 mM	0.016 mL	0.0801 mL	0.1601 mL	0.3202 mL	0.4003 mL