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  • 阿魏酸异丙酯

    Isopropyl ferulate

    阿魏酸异丙酯
    产品编号 CFN93263
    CAS编号 59831-94-6
    分子式 = 分子量 C13H16O4 = 236.26
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Ligusticum chuanxiong Hort.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    阿魏酸异丙酯 CFN93263 59831-94-6 1mg QQ客服:2056216494
    阿魏酸异丙酯 CFN93263 59831-94-6 5mg QQ客服:2056216494
    阿魏酸异丙酯 CFN93263 59831-94-6 10mg QQ客服:2056216494
    阿魏酸异丙酯 CFN93263 59831-94-6 20mg QQ客服:2056216494
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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    PMID: 29553709

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  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Enzyme Res. 2011;2011:718949.
    Synthesis of isopropyl ferulate using silica-immobilized lipase in an organic medium.[Pubmed: 21603272]
    Immobilization of lipases has proved to be a useful technique for improving an enzyme's activity in organic solvents.
    METHODS AND RESULTS:
    In the present study, the performance of a silica-immobilized lipase was evaluated for the synthesis of Isopropyl ferulate in DMSO. The biocatalyst was cross-linked onto the matrix with 1% glutaraldehyde. The effects of various parameters, molar ratio of ferulic acid to isopropyl alcohol (25 mM : 100 mM), concentration of biocatalyst (2.5-20 mg/mL), molecular sieves (25-250 mg/mL), and various salt ions, were studied consecutively as a function of percent esterification. Immobilized lipase at 25 mg/mL showed maximum esterification (~84%) of ferulic acid and isopropanol at a molar ratio of 25 mM : 100 mM, respectively, in DMSO at 45°C in 3 h under shaking (150 rpm).
    CONCLUSIONS:
    To overcome the inhibitory effect of water (a byproduct) if any, in the reaction mixture, molecular sieves (3 Å × 1.5 mm; 100 mg/mL) were added to the reaction mixture to promote the forward reaction. Salt ions like Ca(2+), Cd(2+), and Fe(2+) enhanced the activity of immobilized biocatalyst while a few ions like Co(2+), Zn(2+), Mg(2+), Mn(2+), Al(3+), and Na(+) had mild inhibitory effect. Approximately, one third of total decrease in the esterification efficacy was observed after the 5th repetitive cycle of esterification.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.2326 mL 21.1631 mL 42.3263 mL 84.6525 mL 105.8156 mL
    5 mM 0.8465 mL 4.2326 mL 8.4653 mL 16.9305 mL 21.1631 mL
    10 mM 0.4233 mL 2.1163 mL 4.2326 mL 8.4653 mL 10.5816 mL
    50 mM 0.0847 mL 0.4233 mL 0.8465 mL 1.6931 mL 2.1163 mL
    100 mM 0.0423 mL 0.2116 mL 0.4233 mL 0.8465 mL 1.0582 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    (E)-1-(4-Hydroxyphenyl)dec-1-en-3-one; (E)-1-(4-Hydroxyphenyl)dec-1-en-3-one CFN96131 958631-84-0 C16H22O2 = 246.4 5mg QQ客服:215959384
    紫堇块茎碱; Corytuberine CFN90528 517-56-6 C19H21NO4 = 327.37 5mg QQ客服:1413575084
    芝麻酚; Sesamol CFN90452 533-31-3 C7H6O3 = 138.12 20mg QQ客服:2056216494
    柘树咕吨酮L; Cudraxanthone L CFN99422 135541-40-1 C23H24O6 = 396.4 5mg QQ客服:215959384

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