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  • Epitheaflagallin 3-O-gallate

    Epitheaflagallin 3-O-gallate

    Epitheaflagallin 3-O-gallate
    产品编号 CFN93141
    CAS编号 102067-92-5
    分子式 = 分子量 C27H20O13 = 552.44
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 From Black tea
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Epitheaflagallin 3-O-gallate CFN93141 102067-92-5 1mg QQ客服:1413575084
    Epitheaflagallin 3-O-gallate CFN93141 102067-92-5 5mg QQ客服:1413575084
    Epitheaflagallin 3-O-gallate CFN93141 102067-92-5 10mg QQ客服:1413575084
    Epitheaflagallin 3-O-gallate CFN93141 102067-92-5 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • Michigan State University (USA)
  • Universiti Malaysia Pahang (Malaysia)
  • University of Sao Paulo (Brazil)
  • Universiti Sains Malaysia (Malaysia)
  • The Australian National University (Australia)
  • University of Vienna (Austria)
  • Indian Institute of Science (India)
  • Sri Ramachandra University (India)
  • University of Bordeaux (France)
  • University of Dicle (Turkey)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Centralised Purchases Unit (CPU), B.I.T.S (India)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nat Prod Commun.2018, 10.1177
  • Sci Rep. 2024, 14(1):70.
  • Clin Transl Med.2021, 11(5):e392.
  • Microchemical Journal2022, 182: 107874.
  • Pharmacol Rep.2020, 72(2):472-480.
  • Preprints2022, 2022030063.
  • Molecules.2016, 21(6)
  • VNU J Science: Med.&Pharm. Sci.2024.2588-1132
  • J Ethnopharmacol.2019, 244:112074
  • Biomolecules.2024, 14(5):589.
  • J Appl Biol Chem.2022, 65(4):pp.463-469.
  • bioRxiv - Molecular Biology2023, 535548.
  • Food Research International2020, 108987
  • J Cell Biochem.2018, 119(2):2231-2239
  • Dermatologica Sinica2024, 42(1):p19-30.
  • Planta Med.2023, 2192-2281
  • Food Bioscience2023, 52:102412
  • Sci Rep.2019, 9(1):6429
  • Phytomedicine.2022, 100:154085.
  • Front Cell Infect Microbiol.2018, 8:292
  • Plants (Basel).2022, 11(21):2947.
  • Evid Based Complement Alternat Med.2018, 2018:8565132
  • Pol J Microbiol.2021, 70(1):117-130.
  • ...
  • 生物活性
    Description: Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis. Epitheaflagallin 3-O-gallate also shows antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinus glycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3.
    Targets: MMP(e.g.TIMP)
    In vitro:
    J Agric Food Chem. 2017 Dec 6;65(48):10473-10481.
    Functional Characterization of Epitheaflagallin 3-O-Gallate Generated in Laccase-Treated Green Tea Extracts in the Presence of Gallic Acid.[Pubmed: 29131612]
    Epitheaflagallin (ETFG) and Epitheaflagallin 3-O-gallate (ETFGg) are minor polyphenols in black tea extract that are enzymatically synthesized from epigallocatechin (EGC) and epigallocatechin gallate (EGCg), respectively, in green tea extract via laccase oxidation in the presence of gallic acid.
    METHODS AND RESULTS:
    The constituents of laccase-treated green tea extract in the presence of gallic acid are thus quite different from those of nonlaccase-treated green tea extract: EGC and EGCg are present in lower concentrations, and ETFG and ETFGg are present in higher concentrations. Additionally, laccase-treated green tea extract contains further polymerized catechin derivatives, comparable with naturally fermented teas such as oolong tea and black tea. We found that ETFGg and laccase-treated green tea extracts exhibit versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinus glycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts.
    CONCLUSIONS:
    We confirmed that these inhibitory effects of ETFGg in vitro match well with the results obtained by docking simulations of the compounds with their target enzymes or noncatalytic protein. Thus, ETFGg and laccase-treated green tea extracts containing ETFGg are promising functional food materials with potential antiobesity and antiperiodontal disease activities.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8102 mL 9.0508 mL 18.1015 mL 36.203 mL 45.2538 mL
    5 mM 0.362 mL 1.8102 mL 3.6203 mL 7.2406 mL 9.0508 mL
    10 mM 0.181 mL 0.9051 mL 1.8102 mL 3.6203 mL 4.5254 mL
    50 mM 0.0362 mL 0.181 mL 0.362 mL 0.7241 mL 0.9051 mL
    100 mM 0.0181 mL 0.0905 mL 0.181 mL 0.362 mL 0.4525 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    酒石酸; Tartaric acid CFN93181 87-69-4 C4H6O6 = 150.09 5mg QQ客服:3257982914
    异茜草素; Xanthopurpurin CFN96430 518-83-2 C14H8O4 = 240.21 5mg QQ客服:2056216494
    杜克甙A; Dulcoside A CFN92266 64432-06-0 C38H60O17 = 788.9 5mg QQ客服:1457312923
    Epitheaflagallin 3-O-gallate; Epitheaflagallin 3-O-gallate CFN93141 102067-92-5 C27H20O13 = 552.44 5mg QQ客服:2056216494

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