
Epitheaflagallin 3-O-gallate
Epitheaflagallin 3-O-gallate
产品名称 |
产品编号 |
CAS编号 |
包装 |
QQ客服 |
Epitheaflagallin 3-O-gallate |
CFN93141 |
102067-92-5 |
1mg |
QQ客服:1413575084 |
Epitheaflagallin 3-O-gallate |
CFN93141 |
102067-92-5 |
5mg |
QQ客服:1413575084 |
Epitheaflagallin 3-O-gallate |
CFN93141 |
102067-92-5 |
10mg |
QQ客服:1413575084 |
Epitheaflagallin 3-O-gallate |
CFN93141 |
102067-92-5 |
20mg |
QQ客服:1413575084 |
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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
Institute of Pathophysiology Medical University of Vienna (Austria)
Michigan State University (USA)
Universiti Malaysia Pahang (Malaysia)
University of Sao Paulo (Brazil)
Universiti Sains Malaysia (Malaysia)
The Australian National University (Australia)
University of Vienna (Austria)
Indian Institute of Science (India)
Sri Ramachandra University (India)
University of Bordeaux (France)
University of Dicle (Turkey)
Research Unit Molecular Epigenetics (MEG) (Germany)
Centralised Purchases Unit (CPU), B.I.T.S (India)
More...
国外学术期刊发表的引用ChemFaces产品的部分文献
Description: |
Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis. Epitheaflagallin 3-O-gallate also shows antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinus glycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3. |
Targets: |
MMP(e.g.TIMP) |
In vitro: |
J Agric Food Chem. 2017 Dec 6;65(48):10473-10481. | Functional Characterization of Epitheaflagallin 3-O-Gallate Generated in Laccase-Treated Green Tea Extracts in the Presence of Gallic Acid.[Pubmed: 29131612] | Epitheaflagallin (ETFG) and Epitheaflagallin 3-O-gallate (ETFGg) are minor polyphenols in black tea extract that are enzymatically synthesized from epigallocatechin (EGC) and epigallocatechin gallate (EGCg), respectively, in green tea extract via laccase oxidation in the presence of gallic acid.
METHODS AND RESULTS:
The constituents of laccase-treated green tea extract in the presence of gallic acid are thus quite different from those of nonlaccase-treated green tea extract: EGC and EGCg are present in lower concentrations, and ETFG and ETFGg are present in higher concentrations. Additionally, laccase-treated green tea extract contains further polymerized catechin derivatives, comparable with naturally fermented teas such as oolong tea and black tea. We found that ETFGg and laccase-treated green tea extracts exhibit versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinus glycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts.
CONCLUSIONS:
We confirmed that these inhibitory effects of ETFGg in vitro match well with the results obtained by docking simulations of the compounds with their target enzymes or noncatalytic protein. Thus, ETFGg and laccase-treated green tea extracts containing ETFGg are promising functional food materials with potential antiobesity and antiperiodontal disease activities. |
|
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
1 mM |
1.8102 mL |
9.0508 mL |
18.1015 mL |
36.203 mL |
45.2538 mL |
5 mM |
0.362 mL |
1.8102 mL |
3.6203 mL |
7.2406 mL |
9.0508 mL |
10 mM |
0.181 mL |
0.9051 mL |
1.8102 mL |
3.6203 mL |
4.5254 mL |
50 mM |
0.0362 mL |
0.181 mL |
0.362 mL |
0.7241 mL |
0.9051 mL |
100 mM |
0.0181 mL |
0.0905 mL |
0.181 mL |
0.362 mL |
0.4525 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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