| In vitro: |
| Nat Prod Commun. 2010 Jul;5(7):1127-32. | | Antiproliferative and cytotoxic effects on malignant melanoma cells of essential oils from the aerial parts of Genista sessilifolia and G. tinctoria.[Pubmed: 20734956] | Genista species (family Leguminosae) show interesting biological properties.
METHODS AND RESULTS:
In this paper we describe the biological activity of the essential oils extracted from the aerial parts of G. sessilifolia DC. and G. tinctoria L. against M14 human melanoma cells, testing several biochemical parameters, such as cell vitality, cell membrane integrity and genomic DNA fragmentation. In addition, we report for the first time the study of the composition of the essential oil obtained from G. tinctoria. The most abundant components of the oil were carbonylic compounds such as (E)-beta-ionone (9.1%), Dihydroactinidiolide (7.3%), nonanal (5.1%) and hexahydrofarnesylacetone (4.3%).
CONCLUSIONS:
The essential oils from aerial parts of both G. sessilifolia and G. tinctoria showed interesting potential anticancer activity, suggesting the presence of active compounds. | | Experientia, 1981, 37(11):1133-1133. | | Dihydroactinidiolide—a potent growth inhibitor from Eleocharis coloradoensis (spikerush)[Reference: WebLink] | | Dihydroactinidiolide has been isolated fromEleocharis coloradoensis, along with p-coumaric acid, ferulic acid and luteolin, and shown to be a potent phytotoxin at low concentration. |
|
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)
