Info: Read More
    		•
  • 中药标准品生产商，产品定制服务
    		•
  • 首页
  • 天然产物
  • 产品文献
  • 最新产品
  • 订购流程
  • 公司新闻
  • 公司简介
  • 联系我们
  • 首页
  • /
  • 天然产物（标准品）
  • /
  • D-(-)-水杨苷; D-(-)-水杨甙

    • D-(-)-水杨苷; D-(-)-水杨甙

    D-(-)-Salicin

    D-(-)-水杨苷; D-(-)-水杨甙
    		产品编号 CFN99541
    CAS编号 138-52-3
    分子式 = 分子量 C13H18O7 = 286.27
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The peels of Salix alba L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    D-(-)-水杨苷; D-(-)-水杨甙 CFN99541 138-52-3 10mg QQ客服：2056216494
    D-(-)-水杨苷; D-(-)-水杨甙 CFN99541 138-52-3 20mg QQ客服：2056216494
    D-(-)-水杨苷; D-(-)-水杨甙 CFN99541 138-52-3 50mg QQ客服：2056216494
    D-(-)-水杨苷; D-(-)-水杨甙 CFN99541 138-52-3 100mg QQ客服：2056216494
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

    2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。 但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常，这些可用于长达两周。 使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度，使用和处理的建议？ 请发送电子邮件至：service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话：
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到：027-84254680

    • 提供订购信息
  • 为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号（CAS No.或产品名称）
  • 2. 发货地址
  • 3. 联系方法 (联系人，电话）
  • 4. 开票抬头 (如果需要发票的客户）
  • 5. 发票地址（发货地址与发票地址不同）
    • 发货时间
    1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Srinakharinwirot University (Thailand)
  • Seoul National University of Science and Technology (Korea)
  • Florida International University (USA)
  • Gyeongsang National University (Korea)
  • Uniwersytet Gdański (Poland)
  • University of Lodz (Poland)
  • Istanbul University (Turkey)
  • Helmholtz Zentrum München (Germany)
  • National Research Council of Canada (Canada)
  • Wageningen University (Netherlands)
  • Vin?a Institute of Nuclear Sciences (Serbia)
  • University of Wisconsin-Madison (USA)
  • University of Queensland (Australia)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Anticancer Res.2018, 38(4):2127-2135
  • Mol Pharmacol.2021, 99(2):163-174.
  • Molecules.2020 ,25(16):3697.
  • University of Central Lancashire2017, 20472
  • Molecules.2022, 27(4):1412.
  • Chin J Pharm Anal.2019, 39(7):1217-1228
  • Food Funct.2022, 13(13):6923-6933.
  • J Nat Med.2017, 71(4):745-756
  • Molecules.2018, 23(10):E2638
  • Jeju National University Graduate School2023, 24478
  • Indian J Pharm Sci.2022, 84(4): 874-882.
  • Cancers (Basel).2023, 15(1):37.
  • Int J Mol Sci.2023, 24(8):7045.
  • Turk J Med Sci.2023 53: 1312-1320.
  • Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
  • Regen Biomater.2023, 10:rbad077.
  • BMC Plant Biol.2023, 23(1):239.
  • J Korean Med Obes Res.2023, 23:10-7
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • Planta Med.2018, 84(6-07):465-474
  • J of Apicultural Research2020, 10.1080
  • Mol Plant Pathol.2022, 10.1111:mpp.13280.
  • Exp Parasitol.2017, 183:160-166
  • ...
    • 生物活性
    Description: D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities, it can inhibit the LPS-induced inflammation in RAW264.7 cells and mouse models.
    Targets: TNF-α | MAPK | NF-kB | IL Receptor
    In vitro:
    Int Immunopharmacol. 2015 Jun;26(2):286-94.
    D(-)-Salicin inhibits the LPS-induced inflammation in RAW264.7 cells and mouse models.[Pubmed: 25907238]
    D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities.
    METHODS AND RESULTS:
    The present study aimed to investigate whether D(-)-Salicin inhibited the LPS-induced inflammation in vivo and in vitro. We evaluated the effect of D(-)-Salicin on cytokines (TNF-α, IL-1β, IL-6 and IL-10) in vivo and in vitro by enzyme-linked immunosorbent assay and signaling pathways (MAPKs and NF-κB) in vivo by Western blot. The results showed that D(-)-Salicin markedly decreased TNF-α, IL-1β and IL-6 concentrations and increased IL-10 concentration. In addition, western blot analysis indicated that D(-)-Salicin suppressed the activation of MAPKs and NF-κB signaling pathways stimulated by LPS. To examine whether D(-)-Salicin ameliorated LPS-induced lung inflammation, inhibitors of MAPKs and NF-κB signaling pathways were administrated intraperitoneally to mice. Interference with specific inhibitors revealed that D(-)-Salicin-mediated cytokine suppression was through MAPKs and NF-κB pathways. In the mouse model of acute lung injury, histopathologic examination indicted that D(-)-Salicin suppressed edema induced by LPS.
    CONCLUSIONS:
    So it is suggest that D(-)-Salicin might be a potential therapeutic agent against inflammatory diseases.
    In vivo:
    Int Immunopharmacol. 2015 Jun;26(2):286-94.
    D(-)-Salicin inhibits the LPS-induced inflammation in RAW264.7 cells and mouse models.[Pubmed: 25907238]
    D(-)-Salicin is a traditional medicine which has been known to exhibit anti-inflammation and other therapeutic activities.
    METHODS AND RESULTS:
    The present study aimed to investigate whether D(-)-Salicin inhibited the LPS-induced inflammation in vivo and in vitro. We evaluated the effect of D(-)-Salicin on cytokines (TNF-α, IL-1β, IL-6 and IL-10) in vivo and in vitro by enzyme-linked immunosorbent assay and signaling pathways (MAPKs and NF-κB) in vivo by Western blot. The results showed that D(-)-Salicin markedly decreased TNF-α, IL-1β and IL-6 concentrations and increased IL-10 concentration. In addition, western blot analysis indicated that D(-)-Salicin suppressed the activation of MAPKs and NF-κB signaling pathways stimulated by LPS. To examine whether D(-)-Salicin ameliorated LPS-induced lung inflammation, inhibitors of MAPKs and NF-κB signaling pathways were administrated intraperitoneally to mice. Interference with specific inhibitors revealed that D(-)-Salicin-mediated cytokine suppression was through MAPKs and NF-κB pathways. In the mouse model of acute lung injury, histopathologic examination indicted that D(-)-Salicin suppressed edema induced by LPS.
    CONCLUSIONS:
    So it is suggest that D(-)-Salicin might be a potential therapeutic agent against inflammatory diseases.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4932 mL 17.466 mL 34.9321 mL 69.8641 mL 87.3301 mL
    5 mM 0.6986 mL 3.4932 mL 6.9864 mL 13.9728 mL 17.466 mL
    10 mM 0.3493 mL 1.7466 mL 3.4932 mL 6.9864 mL 8.733 mL
    50 mM 0.0699 mL 0.3493 mL 0.6986 mL 1.3973 mL 1.7466 mL
    100 mM 0.0349 mL 0.1747 mL 0.3493 mL 0.6986 mL 0.8733 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Pyrocallianthaside A; Pyrocallianthaside A CFN95675 1004783-55-4 C26H34O14 = 570.6 5mg QQ客服：2159513211
    新化合物31; New compound 31 CFN95699 N/A C26H34O14 = 570.6 5mg QQ客服：1413575084
    新化合物32; New compound 32 CFN95700 N/A C39H50O21 = 854.8 5mg QQ客服：3257982914
    Pyrolaside A; Pyrolaside A CFN95671 868632-29-5 C26H34O14 = 570.6 10mg QQ客服：1413575084
    新化合物28; New compound 28 CFN95689 N/A C32H44O19 = 732.7 5mg QQ客服：2159513211
    新化合物30; New compound 30 CFN95695 N/A C26H34O14 = 570.6 5mg QQ客服：215959384
    Pyrolaside B; Pyrolaside B CFN95674 868632-32-0 C39H50O21 = 854.8 5mg QQ客服：1457312923
    新化合物29; New compound 29 CFN95693 N/A C39H50O21 = 854.8 5mg QQ客服：215959384
    Pyrolaside B analogue; Pyrolaside B analogue CFN95687 1053610-99-3 C39H50O21 = 854.8 5mg QQ客服：1457312923
    新化合物27; New compound 27 CFN95688 N/A C39H50O22 = 870.8 5mg QQ客服：3257982914

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

    联系方式


    电机：027-84237783
    传真：027-84254680
    在线QQ: 1413575084
    E-Mail：manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。