| In vitro: |
| Chinese Journal of Experimental Traditional Medical Formulae, 2012, 18(24):162-6. | | Chemical Constituents from Cibotium barometz and their Scavenging Activities for DPPH Radical.[Reference: WebLink] | Study on the chemical constituents from Cibotium barometz and their scavenging activities for 2,2-diphenyl-2-picrylhydrazyl(DPPH) radical.
METHODS AND RESULTS:
The chemical constituent from70% alcohol extract of C.barometz was isolated on chromatograph of silica gel and sephadex LH-20 and HPLC,their structure were elucidated on the basis of spectra data and the compounds were tested for their scavenging activities on DPPH radical.Ten compounds were purified and their structure were identified as 1-O-caffeyl-D-glucopyranose(1),6-O-caffeyl-D-glucopyranose(2),3-O-caffeyl-D-glucopyranose(3),3-hydroxymethyl-2(5H)-furanone(4),β-miroside(5),cibotiumbaroside A(6),protocatechuic acid(7),glucose(8),mannose(9),Corchoionoside C(10),kojic acid(11).Three isolated compounds showed strong scavenging activities on DPPH radical.
CONCLUSIONS:
Compound 1-5 were isolated for the first time from C.barometz.among of them,compound 1,compound 3 and compound 6 showed significant antioxidant activity,and the scavenging activity of compound 1 was similar to that of Vit C. | | Nat Prod Res. 2011 Jan;25(1):1-7. | | Isoswertisin flavones and other constituents from Peperomia obtusifolia.[Pubmed: 21240754 ] |
METHODS AND RESULTS:
A phytochemical investigation of the leaves and stems of Peperomia obtusifolia (Piperaceae) yielded a new flavone C-diglycoside isoswertisin-4'-methyl-ether-2''α-L-rhamnoside (1), along with four known compounds: isoswertisin-2''α-L-rhamnoside (2), (+)-diayangambin (3), 2-episesalatin (4) and corchoionoside C (5). The structures of the two flavone C-diglycosides (1, 2) were elucidated on the basis of 1D and 2D NMR spectroscopy and MS spectrometric data.
CONCLUSIONS:
These flavones were evaluated by bioautographic assay against Cladosporium cladosporioides and C. sphaerospermum and showed weak antifungal activity. |
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