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  • Calystegine N1

    Calystegine N1

    Calystegine N1
    产品编号 CFN00146
    CAS编号 177794-03-5
    分子式 = 分子量 C7H14N2O3 = 174.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The leaves of Morus alba L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Calystegine N1 CFN00146 177794-03-5 1mg QQ客服:2056216494
    Calystegine N1 CFN00146 177794-03-5 5mg QQ客服:2056216494
    Calystegine N1 CFN00146 177794-03-5 10mg QQ客服:2056216494
    Calystegine N1 CFN00146 177794-03-5 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Front Immunol. 2020, 11:62.
  • National Academy Science Letters2023, s40009.
  • Molecules.2023, 28(16):6025.
  • Environ Toxicol.2023, 38(5):1174-1184.
  • J Neuroinflammation.2023, 20(1):268.
  • BMC Complement Altern Med.2019, 19(1):325
  • Food Chem X.2024, 21:101208.
  • Curr Issues Mol Biol.2023, 45(3):2136-2156.
  • Front Pharmacol.2021, 12:761922.
  • Biochem Biophys Res Commun.2021, 534:802-807.
  • Dis Markers.2022, 2022:2380879.
  • Biomed Pharmacother.2023, 166:115329.
  • Molecules.2024, 29(5):1050.
  • Evid Based Complement Alternat Med.2017, 2017:1583185
  • J AOAC Int.2023, 106(1):56-64.
  • J Chromatogr B Analyt Technol Biomed Life Sci.2022, 1203:123307.
  • Molecules.2016, 21(6)
  • Universitat Stuttgart2022, opus-12200.
  • BMC Plant Biol.2018, 18(1):122
  • Int J Mol Sci.2023, 24(20):15320.
  • iScience.2024, 4790628.
  • Biol Pharm Bull.2020, 43(10):1534-1541.
  • J Adv Res.2021, 35:245-257.
  • ...
  • 生物活性
    Description: Calystegin N~ is a weaker inhibitor of glycosidases.
    In vitro:
    ChemInform, 1996, 27(33).
    Calystegin N1, a Novel Nortropane Alkaloid with a Bridgehead Amino Group from Hyoscyamus niger: Structure Determination and Glycosidase Inhibitory Activities.[Reference: WebLink]

    METHODS AND RESULTS:
    Seven calystegins were isolated from the whole plant of Hyoscyamus niger. They are calystegins A 3, A 5, A 6, B t , B 2, B 3, and N 1. The structure of new calystegin A 6 was determined as la,2~,7a-trihydroxy-nor-tropane, and another new calystegine N1 was elucidated to be a trihydroxy-nor-tropane alkaloid with a bridgehead NH 2 group in the place of a bridgehead OH group in calystegin B 2. Very interestingly, on storage for a half year in a refrigerator, approximately 40% of calystegin N I was nonenzymically converted into calystegin B 2.
    CONCLUSIONS:
    Calystegin N~ was a weaker inhibitor of glycosidases compared to calystegin B 2 but with the same inhibitory spectrum. However, calystegin N~ inhibited porcine kidney trehalase in a noncompetitive manner, whereas calystegin B 2 inhibited this enzyme in a competitive manner.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.7405 mL 28.7026 mL 57.4053 mL 114.8106 mL 143.5132 mL
    5 mM 1.1481 mL 5.7405 mL 11.4811 mL 22.9621 mL 28.7026 mL
    10 mM 0.5741 mL 2.8703 mL 5.7405 mL 11.4811 mL 14.3513 mL
    50 mM 0.1148 mL 0.5741 mL 1.1481 mL 2.2962 mL 2.8703 mL
    100 mM 0.0574 mL 0.287 mL 0.5741 mL 1.1481 mL 1.4351 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    8-Azabicyclo[3.2.1]octane-2,3-diol; 8-Azabicyclo[3.2.1]octane-2,3-diol CFN00152 N/A C7H13NO2 = 143.18 5mg QQ客服:1413575084
    包公藤丙素; Baogongteng C CFN00154 107259-50-7 C7H13NO2 = 143.18 5mg QQ客服:1457312923
    包公藤甲素; Baogongteng A CFN00155 74239-84-2 C9H15NO3 = 185.22 5mg QQ客服:2056216494
    2,6-Tropanediol; 2,6-Tropanediol CFN00156 65356-02-7 C8H15NO2 = 157.21 5mg QQ客服:2056216494
    Erycibelline; Erycibelline CFN00157 107633-95-4 C7H13NO2 = 143.18 5mg QQ客服:1413575084
    8-Azabicyclo[3.2.1]octane-3,6-diol; 8-Azabicyclo[3.2.1]octane-3,6-diol CFN00158 N/A C7H13NO2 = 143.18 5mg QQ客服:2159513211
    3,6-双马豆酰基去甲莨菪烷; 3,6-Ditigloyloxynortropane CFN00159 359723-70-9 C17H25NO4 = 307.39 5mg QQ客服:1413575084
    Calystegine C2; Calystegine C2 CFN00160 190957-44-9 C7H13NO5 = 191.18 5mg QQ客服:1413575084
    Calystegine B2; Calystegine B2 CFN00161 127414-85-1 C7H13NO4 = 175.18 5mg QQ客服:215959384
    Calystegine B3; Calystegine B3 CFN00162 178231-95-3 C7H13NO4 = 175.18 5mg QQ客服:1413575084

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