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  • 左旋羟脯氨酸二甲内盐

    Betonicine

    左旋羟脯氨酸二甲内盐
    产品编号 CFN70389
    CAS编号 515-25-3
    分子式 = 分子量 C7H13NO3 = 159.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The herbs of Beta vulgaris L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    左旋羟脯氨酸二甲内盐 CFN70389 515-25-3 1mg QQ客服:2056216494
    左旋羟脯氨酸二甲内盐 CFN70389 515-25-3 5mg QQ客服:2056216494
    左旋羟脯氨酸二甲内盐 CFN70389 515-25-3 10mg QQ客服:2056216494
    左旋羟脯氨酸二甲内盐 CFN70389 515-25-3 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Subang Jaya Medical Centre (Malaysia)
  • Universidade da Beira Interior (Germany)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • University of Otago (New Zealand)
  • Pennsylvania State University (USA)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Regional Crop Research Institute (Korea)
  • Universidad de Buenos Aires (Argentina)
  • Northeast Normal University Changchun (China)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Rio de Janeiro State University (Brazil)
  • China Medical University (Taiwan)
  • University of Queensland (Australia)
  • Univerzita Karlova v Praze (Czech Republic)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Res Rep Urol.2022, 14:313-326.
  • Food Chem.2019, 290:286-294
  • Front Pharmacol.2020, 11:251.
  • Int J Mol Sci.2024, 25(6):3390.
  • Biomed Pharmacother.2022, 156:113929.
  • Naunyn Schmiedebergs Arch Pharmacol.2021, 394(1):107-115.
  • Evid Based Complement Alternat Med.2021, 2021:5585692.
  • Microorganisms.2021, 9(12):2514.
  • In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
  • Sci Rep.2019, 9(1):4646
  • Phytomedicine.2019, 58:152893
  • J Food Sci.2024, 3841.17112.
  • Plant Sci.2020, 301:110656.
  • Pharm Biol.2022, 60(1):2040-2048.
  • Phytomedicine.2018, 40:37-47
  • J Sci Food Agric.2023, 103(1):213-220.
  • Journal of Functional Foods2022, 98:105271.
  • Industrial Crops and Products2022, 186:115298
  • Biocell2023, 47(8):1793-1802
  • FEBS Lett.2021, 595(20):2608-2615.
  • J Pharm Biomed Anal.2017, 140:274-280
  • Biol Pharm Bull.2018, 41(11):1645-1651
  • J Biomed Sci.2020, 27(1):60.
  • ...
  • 生物活性
    Description: Betonicine will be useful for elucidating the interaction between OHL and TraR, and for developing novel bacterial quorum-sensing inhibitors.
    Targets: Antifection
    In vitro:
    Biotechnology and bioprocess engineering, 2008, 13(4):458-463.
    The effects of betonicine, floridoside, and isethionic acid from the red alga Ahnfeltiopsis flabelliformis on quorum-sensing activity.[Reference: WebLink]

    METHODS AND RESULTS:
    A mixture of three compounds (betonicine, floridoside, and isethionic acid) purified from the red alga Ahnfeltiopsis flabelliformis, was reported to have an inhibition activity on bacterial quorum sensing mechanism mediated by Noctanoyl-DL-homoserine lactone (OHL) and the TraR transcriptional activator protein. We subsequently conducted a more detailed investigation of the three compounds using chemically synthesized (betonicine and floridoside) or commercially available (isethionic acid) compounds, individually or in various combinations. When tested alone, none of the three compounds inhibited OHL, but a mixture of floridoside and isethionic acid exhibited a dose-dependent inhibitory effect on the function of OHL. In contrast, betonicine or its isomer exhibited a dose-dependent stimulatory effect, similar to OHL, at concentrations between 10−3 and 10−6 M.
    CONCLUSIONS:
    These three compounds will be useful for elucidating the interaction between OHL and TraR, and for developing novel bacterial quorum-sensing inhibitors.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.2814 mL 31.407 mL 62.8141 mL 125.6281 mL 157.0352 mL
    5 mM 1.2563 mL 6.2814 mL 12.5628 mL 25.1256 mL 31.407 mL
    10 mM 0.6281 mL 3.1407 mL 6.2814 mL 12.5628 mL 15.7035 mL
    50 mM 0.1256 mL 0.6281 mL 1.2563 mL 2.5126 mL 3.1407 mL
    100 mM 0.0628 mL 0.3141 mL 0.6281 mL 1.2563 mL 1.5704 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    吡唑蒽酮(SP600125); Pyrazolanthrone (SP600125) CFN60010 129-56-6 C14H8N2O = 220.23 5mg QQ客服:215959384
    Daphnicyclidin D ; Daphnicyclidin D CFN96777 385384-24-7 C23H27NO4 = 381.47 5mg QQ客服:2056216494
    20-甲氧基人参皂苷Rg3; 20-Methoxyginsenoside Rg3 CFN95763 N/A C43H74O13 = 799.1 10mg QQ客服:1457312923
    瓦托品; Valtropine CFN00210 495-82-9 C13H23NO2 = 225.33 5mg QQ客服:3257982914

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