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  • Beta-Dimorphecolic acid

    Beta-Dimorphecolic acid (9(S)-HODE)

    Beta-Dimorphecolic acid
    产品编号 CFN95313
    CAS编号 18104-44-4
    分子式 = 分子量 C18H32O3 = 296.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lipids
    植物来源 The herbs of Piper cubeba
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Beta-Dimorphecolic acid CFN95313 18104-44-4 1mg QQ客服:2159513211
    Beta-Dimorphecolic acid CFN95313 18104-44-4 5mg QQ客服:2159513211
    Beta-Dimorphecolic acid CFN95313 18104-44-4 10mg QQ客服:2159513211
    Beta-Dimorphecolic acid CFN95313 18104-44-4 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Ioannina (Greece)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • University of Bordeaux (France)
  • Sant Gadge Baba Amravati University (India)
  • University of Brasilia (Brazil)
  • Universidade do Porto (Portugal)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • University of Beira Interior (Portugal)
  • Chinese University of Hong Kong (China)
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  • Universite Libre de Bruxelles (Belgium)
  • Universidad Veracuzana (Mexico)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutr Res Pract.2020, 14(3):203-217.
  • Universidade Estadual Paulista2017, 11449
  • J Cell Mol Med.2023, jcmm.17968.
  • Am J Chin Med.2016, 44(8):1719-1735
  • Antioxidants (Basel).2022, 11(1):171.
  • Nutrients2023, 15(18), 4016.
  • Arch Toxicol.2017, 91(10):3225-3245
  • Sci Rep.2021, 11(1):10931.
  • J.of Traditional&Complementary Med.2022, 10.1016:j.jtcme.
  • Food Funct.2024, 15(8):4262-4275.
  • Nanjing University of Chinese Medicine2022, 345930.
  • J Nat Med.2017, 71(2):380-388
  • Phytochemistry.2021, 181:112539.
  • The Journal of Supercritical Fluids2021, 176:105305.
  • Biochem Biophys Res Commun.2018, 505(1):261-266
  • Applied Biological Chem. 2020, 26(63).
  • J of Pharmaceutical Analysis2020, doi: 10.1016
  • Saudi Pharm J2020, 10.1016
  • Archives of Biological sciences2022, 00:21-21
  • J Nat Prod.2021, 84(9):2544-2553.
  • Molecules.2021, 26(6):1635.
  • Food and Fermentation Industries2019, 45(7):45-51
  • University of Limpopo2016, 1-237
  • ...
  • 生物活性
    Description: Anti-inflammatory activity.
    In vitro:
    Pharmacogn Mag . Jul-Sep 2015;11(43):477-85
    A direct protein kinase B-targeted anti-inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris[Pubmed: 26246722]
    Background: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities. Objective: The objective of the following study is to isolate chemical components from the ethanol extract (Cm-EE) from Cordyceps militaris and to evaluate their anti-inflammatory activities. Materials and methods: Column chromatographic separation was performed and anti-inflammatory roles of these compounds were also examined by using NO production and protein kinase B (AKT) activity assays. Results: From Cm-EE, 13 constituents, including trehalose (1), cordycepin (2), 6-hydroxyethyladenosine (3), nicotinic amide (4), butyric acid (5), β-dimorphecolic acid (6), α-dimorphecolic acid (7), palmitic acid (8), linoleic acid (9), cordycepeptide A (10), 4-(2-hydroxy-3-((9E,12E)-octadeca-9,12-dienoyloxy)propoxy)-2-(trimethylammonio)butanoate (11), 4-(2-hydroxy-3-(palmitoyloxy)propoxy)-2-(trimethylammonio)butanoate (12), and linoleic acid methyl ester (13) were isolated. Of these components, compound 2 displayed a significant inhibitory effect on NO production in lipopolysaccharide (LPS)-activated RAW264.7 cells. Furthermore, this compound strongly and directly suppressed the kinase activity of AKT, an essential signalling enzyme in LPS-induced NO production, by interacting with its ATP binding site. Conclusion: C. militaris could have anti-inflammatory activity mediated by cordycepin-induced suppression of AKT.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3727 mL 16.8634 mL 33.7268 mL 67.4536 mL 84.317 mL
    5 mM 0.6745 mL 3.3727 mL 6.7454 mL 13.4907 mL 16.8634 mL
    10 mM 0.3373 mL 1.6863 mL 3.3727 mL 6.7454 mL 8.4317 mL
    50 mM 0.0675 mL 0.3373 mL 0.6745 mL 1.3491 mL 1.6863 mL
    100 mM 0.0337 mL 0.1686 mL 0.3373 mL 0.6745 mL 0.8432 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    二氢柯楠因; Dihydrocorynantheine CFN92844 4684-43-9 C22H28N2O3 = 368.5 5mg QQ客服:2159513211
    6-Hydroxy-7-methoxydihydroligustilide; 6-Hydroxy-7-methoxydihydroligustilide CFN95289 210036-09-2 C13H18O4 = 238.3 5mg QQ客服:215959384
    四氢胡椒碱; Tetrahydropiperin CFN90870 23434-88-0 C17H23NO3 = 289.4 20mg QQ客服:2056216494
    15Alpha-羟基贝壳杉-16-烯-19-酸; Grandifloric acid CFN97780 22338-69-8 C20H30O3 = 318.46 5mg QQ客服:215959384

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