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  • Beta-Dimorphecolic acid

    Beta-Dimorphecolic acid (9(S)-HODE)

    Beta-Dimorphecolic acid
    产品编号 CFN95313
    CAS编号 18104-44-4
    分子式 = 分子量 C18H32O3 = 296.5
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lipids
    植物来源 The herbs of Piper cubeba
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Beta-Dimorphecolic acid CFN95313 18104-44-4 1mg QQ客服:215959384
    Beta-Dimorphecolic acid CFN95313 18104-44-4 5mg QQ客服:215959384
    Beta-Dimorphecolic acid CFN95313 18104-44-4 10mg QQ客服:215959384
    Beta-Dimorphecolic acid CFN95313 18104-44-4 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Sci Food Agric.2023, 103(1):213-220.
  • Vojnosanit Pregl2016, 75(00):391-391
  • Pharmaceutics.2020, 12(9):845.
  • Iranian J. Pharm. Res.2021, 20(4):59-70
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  • Fermentation2023, 9(10), 889
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  • Korean J. Medicinal Crop Sci.2023, 31(6):388-395.
  • Molecules.2021, 26(8):2161.
  • Cancer Lett. 2023, 18:216584.
  • Plants (Basel).2020, 9(11):1422.
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  • Revista Brasileira de Farmacognosia2021, 31:794-804.
  • Naunyn Schmiedebergs Arch Pharmacol.2021, 394(1):107-115.
  • Appl. Sci.2023, 13(2), 860.
  • Heliyon.2023, 9(11):e21944.
  • ...
  • 生物活性
    Description: Anti-inflammatory activity.
    In vitro:
    Pharmacogn Mag . Jul-Sep 2015;11(43):477-85
    A direct protein kinase B-targeted anti-inflammatory activity of cordycepin from artificially cultured fruit body of Cordyceps militaris[Pubmed: 26246722]
    Background: Cordyceps militaris is one of well-known medicinal mushrooms with anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity activities. Objective: The objective of the following study is to isolate chemical components from the ethanol extract (Cm-EE) from Cordyceps militaris and to evaluate their anti-inflammatory activities. Materials and methods: Column chromatographic separation was performed and anti-inflammatory roles of these compounds were also examined by using NO production and protein kinase B (AKT) activity assays. Results: From Cm-EE, 13 constituents, including trehalose (1), cordycepin (2), 6-hydroxyethyladenosine (3), nicotinic amide (4), butyric acid (5), β-dimorphecolic acid (6), α-dimorphecolic acid (7), palmitic acid (8), linoleic acid (9), cordycepeptide A (10), 4-(2-hydroxy-3-((9E,12E)-octadeca-9,12-dienoyloxy)propoxy)-2-(trimethylammonio)butanoate (11), 4-(2-hydroxy-3-(palmitoyloxy)propoxy)-2-(trimethylammonio)butanoate (12), and linoleic acid methyl ester (13) were isolated. Of these components, compound 2 displayed a significant inhibitory effect on NO production in lipopolysaccharide (LPS)-activated RAW264.7 cells. Furthermore, this compound strongly and directly suppressed the kinase activity of AKT, an essential signalling enzyme in LPS-induced NO production, by interacting with its ATP binding site. Conclusion: C. militaris could have anti-inflammatory activity mediated by cordycepin-induced suppression of AKT.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3727 mL 16.8634 mL 33.7268 mL 67.4536 mL 84.317 mL
    5 mM 0.6745 mL 3.3727 mL 6.7454 mL 13.4907 mL 16.8634 mL
    10 mM 0.3373 mL 1.6863 mL 3.3727 mL 6.7454 mL 8.4317 mL
    50 mM 0.0675 mL 0.3373 mL 0.6745 mL 1.3491 mL 1.6863 mL
    100 mM 0.0337 mL 0.1686 mL 0.3373 mL 0.6745 mL 0.8432 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    3,5-二溴-4-[3-(二甲胺基)丙氧基]肉桂酸; 3,5-Dibromo-4-[3-(dimethylamino)propoxy]cinnamic acid CFN00072 134276-56-5 C14H17Br2NO3 = 407.1 5mg QQ客服:1413575084
    IWR-1-endo; IWR-1-endo CFN60085 1127442-82-3 C25H19N3O3 = 409.44 5mg QQ客服:215959384
    四氢嘧啶; Ectoine CFN91522 96702-03-3 C6H10N2O2 = 142.2 20mg QQ客服:1413575084
    Myrciaphenone A; Myrciaphenone A CFN96697 26089-54-3 C14H18O9 = 330.3 5mg QQ客服:3257982914

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