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  • 交链孢霉烯

    Altenuene

    交链孢霉烯
    产品编号 CFN89098
    CAS编号 29752-43-0
    分子式 = 分子量 C15H16O6 = 292.28
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The culture of the endolichenic fungus Ulocladium sp.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    交链孢霉烯 CFN89098 29752-43-0 1mg QQ客服:1413575084
    交链孢霉烯 CFN89098 29752-43-0 5mg QQ客服:1413575084
    交链孢霉烯 CFN89098 29752-43-0 10mg QQ客服:1413575084
    交链孢霉烯 CFN89098 29752-43-0 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Leipzig (Germany)
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • University of Otago (New Zealand)
  • Charles Sturt University (Denmark)
  • Complutense University of Madrid (Spain)
  • University of South Australia (Australia)
  • Gyeongsang National University (Korea)
  • University of Madras (India)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • CSIRO - Agriculture Flagship (Australia)
  • S.N.D.T. Women's University (India)
  • John Innes Centre (United Kingdom)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Heliyon.2023, e12684.
  • Front. Pharmacol.2022, 901563.
  • Plants (Basel).2021, 10(11):2525.
  • Geroscience.2024, 01207-y.
  • J Ethnopharmacol.2017, 198:87-90
  • Turk J Med Sci.2023 53: 1312-1320.
  • Applied Biological Chemistry2023, 66:8
  • J of Archaeological Science:Reports2024, 53:104298
  • Sci Rep.2021, 11(1):11936.
  • Sci Rep.2017, 7:46299
  • Antioxidants (Basel).2022, 11(12):2411.
  • Antioxidants (Basel).2020, 9(11):1121.
  • Int J Mol Sci.2023, 25(1):162.
  • Food Chem.2021, 360:130063.
  • Mol Pharm.2018, 15(8):3285-3296
  • Biosci Rep.2020, 40(8):BSR20201219.
  • Sci. Rep.2015, 14-23
  • Life (Basel).2023, 13(2):457.
  • Plant Foods Hum Nutr.2020, 10.1007
  • Molecules 2021, 26(4),1092.
  • Molecules2022, 27(9):2613.
  • Front Microbiol.2023, 14:1232039.
  • Int J Anal Chem.2017, 2017:1254721
  • ...
  • 生物活性
    Description: Altenuene is a mycotoxin, it frequently occurs in food and feed items infested by fungi of the genus Alternaria. Altenuene demonstrates moderate activity against Staphylococcus aureus. Altenuene also exhibits cytotoxic activity against lung cancer cell line A549, breast cancer cell line MDA-MB-231 and pancreatic cancer cell line PANC-1.
    Targets: Antifection
    In vitro:
    Fitoterapia. 2012 Jan;83(1):209-14.
    Polyketides with antimicrobial activity from the solid culture of an endolichenic fungus Ulocladium sp.[Pubmed: 22061662 ]

    METHODS AND RESULTS:
    Two new polyketides, 7-hydroxy-3, 5-dimethyl-isochromen-1-one (1) and 6-hydroxy-8-methoxy-3a-methyl-3a,9b-dihydro-3H-furo[3,2-c]isochromene-2,5-dione (2), along with eleven known compounds, 5'-methoxy-6-methyl-biphenyl-3,4,3'-triol (3), 7-hydroxy-3-(2-hydroxy-propyl)-5-methyl-isochromen-1-one (4), rubralactone (5), isoAltenuene (6), Altenuene (7), dihydroAltenuenes A (8), altenusin (9), alterlactone (10), 6-O-methylnorlichexanthone (11), norlichexanthone (12), and griseoxanthone C (13) were isolated from the culture of the endolichenic fungus Ulocladium sp. Compound 2 was obtained as a racemate with an unprecedented chemical skeleton. The NMR data assignments for 3 and 4 were achieved for the first time. Compounds 1-13 were screened for their antimicrobial and radical scavenging activities.
    CONCLUSIONS:
    Compound 1 showed some antifungal activity against Candida albicans SC 5314 with IC(50) of 97.93 ± 1.12 μM. Compounds 11-13 showed strong activity against Bacillus subtilis with IC(50) in the range of 1-5 μM. Compound 12 significantly inhibited the growth of methicillin-resistant Staphylococcus aureus with IC(50) of 20.95 ± 1.56 μM. Compounds 9 and 10 showed strong radical scavenging activity in comparison with vitamin C. The plausible biosynthetic pathways for compounds 1, 2, and 4-8 were discussed.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4214 mL 17.1069 mL 34.2138 mL 68.4275 mL 85.5344 mL
    5 mM 0.6843 mL 3.4214 mL 6.8428 mL 13.6855 mL 17.1069 mL
    10 mM 0.3421 mL 1.7107 mL 3.4214 mL 6.8428 mL 8.5534 mL
    50 mM 0.0684 mL 0.3421 mL 0.6843 mL 1.3686 mL 1.7107 mL
    100 mM 0.0342 mL 0.1711 mL 0.3421 mL 0.6843 mL 0.8553 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    人参皂苷TN2; Gynosaponin TN2 CFN95331 77658-95-8 C42H72O13 = 785.0 5mg QQ客服:2159513211
    氯吡格雷杂质 B; Clopidogrel Related Compound B CFN90547 144750-52-7 C16H17ClNO2SCl = 358.3 5mg QQ客服:2056216494
    Dodovislactone A; Dodovislactone A CFN89105 1616683-54-5 C18H26O4 = 306.40 5mg QQ客服:1413575084
    鹤庆五味子辛素; Schisanwilsonin H CFN92350 1181216-83-0 C30H32O9 = 536.6 5mg QQ客服:2159513211

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