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  • 4-羟基苯甲酸

    • 4-羟基苯甲酸

    4-Hydroxybenzoic acid

    4-羟基苯甲酸
    		产品编号 CFN97577
    CAS编号 99-96-7
    分子式 = 分子量 C7H6O3 = 138.1
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The herbs of Rhodiola crenulata.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    4-羟基苯甲酸 CFN97577 99-96-7 10mg QQ客服：215959384
    4-羟基苯甲酸 CFN97577 99-96-7 20mg QQ客服：215959384
    4-羟基苯甲酸 CFN97577 99-96-7 50mg QQ客服：215959384
    4-羟基苯甲酸 CFN97577 99-96-7 100mg QQ客服：215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Tohoku University (Japan)
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  • University of Hertfordshire (United Kingdom)
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    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nutrients2022, 14(3),695.
  • University of Central Lancashire2017, 20472
  • Molecules.2024, 29(3):671.
  • ACS Omega2020, 5,33,20825-20830
  • Korean J. Medicinal Crop Sci.2022, 30(2):117-123.
  • Nat Prod Commun.2018, 10.1177
  • JPC-Journal of Planar Chromatography2023, 36:179-190
  • Int J Mol Sci.2022, 23(11):6104.
  • J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
  • Metabolites.2019, 9(11):E271
  • Carbohydrate Polymer Technologies & App.2021, 2:100049.
  • BMC Complement Med Ther. 2020, 20(1):94.
  • Food Analytical Methods2020, 13,1603-1612(2020)
  • ACS Omega.2023, 9(1):1278-1286.
  • J.of Traditional&Complementary Med.2022, 10.1016:j.jtcme.
  • Food Chem.2019, 274:345-350
  • Food Chem.2020, 332:127412
  • Dent Mater J.2020, 39(4):690-695
  • Environ Toxicol.2023, 38(7):1641-1650.
  • J Biochem Mol Toxicol.2020, 34(7):e22489.
  • Int J Mol Sci.2023, 24(14):11496.
  • J Food Sci.2024, 3841.17112.
  • Cancers (Basel).2021, 13(6):1432.
  • ...
    • 生物活性
    Description: 4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. 4-Hydroxybenzoic acid derivatives has potential to as pan-HDAC inhibitors with anticancer properties. 4-Hydroxybenzoic acid positively regulates the expression of gum cluster to promote EPS production in PXO99A; it can inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL.
    Targets: HDAC | Antifection
    In vitro:
    Biosci Biotechnol Biochem. 1998 Nov;62(11):2273-6.
    Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull.[Pubmed: 9972252 ]

    METHODS AND RESULTS:
    Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms.
    CONCLUSIONS:
    Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 micrograms/ml, respectively.
    Int. J.Pharmaceut. Sci. Rev. Res., 2013, 22(2): 109-15.
    A Comprehensive Review on Biological activities of p-hydroxy benzoic acid and its derivatives.[Reference: WebLink]
    p-hydroxy benzoic acid (PHBA) is an organic chemical which can be obtained naturally as well as synthetically. The literature survey reveals its various biological properties viz. antimicrobial, antialgal, antimutagenic, antiestrogenic, hypoglycemic, anti-inflammatory, anti-platelet aggregating, nematicidal, antiviral, antioxidant etc. It is also reported to be used as preservative in many drugs, cosmetic products, pharmaceuticals, food and beverages. Some derivatives of 4-Hydroxybenzoic acid are found to possess direct action on Hbs molecules, inhibit acetic acid induced oedema and used in management of sickle cell disease.
    CONCLUSIONS:
    The present study will give comprehensive information of the biological activities of this p-hydroxy benzoic acid and its derivatives.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 7.2411 mL 36.2056 mL 72.4113 mL 144.8226 mL 181.0282 mL
    5 mM 1.4482 mL 7.2411 mL 14.4823 mL 28.9645 mL 36.2056 mL
    10 mM 0.7241 mL 3.6206 mL 7.2411 mL 14.4823 mL 18.1028 mL
    50 mM 0.1448 mL 0.7241 mL 1.4482 mL 2.8965 mL 3.6206 mL
    100 mM 0.0724 mL 0.3621 mL 0.7241 mL 1.4482 mL 1.8103 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    乙酰天麻素; Acetagastrodin CFN80033 64291-41-4 C21H26O11 = 454.43 5mg QQ客服：3257982914
    鹿梨苷; Calleryanin CFN95556 20300-53-2 C13H18O8 = 302.3 5mg QQ客服：1413575084
    原儿茶酸4-O-beta-葡萄糖苷; Protocatechuic acid 4-O-beta-glucoside CFN95557 7361-59-3 C13H16O9 = 316.3 5mg QQ客服：2159513211
    Odontoside; Odontoside CFN95530 20300-50-9 C20H22O11 = 438.4 5mg QQ客服：1413575084
    (3,4-Dihydroxyphenyl)methyl 3-(beta-D-glucopyranosyloxy)-4-hydroxybenzoate; (3,4-Dihydroxyphenyl)methyl 3-(beta-D-glucopyranosyloxy)-4-hydroxybenzoate CFN95531 877461-90-0 C20H22O11 = 438.4 10mg QQ客服：3257982914
    原儿茶酰鹿梨苷-3-O-beta-葡萄糖苷; Protocatechuoylcalleryanin-3-O-beta-glucopyranoside CFN95610 1263431-59-9 C26H32O16 = 600.5 10mg QQ客服：2056216494
    咖啡酰基鹿梨苷; Caffeoylcalleryanin CFN95532 20300-49-6 C22H24O11 = 464.4 10mg QQ客服：1457312923
    对羟基苯乙醇; 2-(4-Hydroxyphenyl)ethanol CFN98792 501-94-0 C8H10O2 = 138.2 20mg QQ客服：215959384
    4-(2-羟乙基)苯甲酸; 4-(2-Hydroxyethyl)benzoic acid CFN95623 46112-46-3 C9H10O3 = 166.2 20mg QQ客服：2056216494
    红景天苷; Salidroside CFN99177 10338-51-9 C14H20O7 = 300.30 20mg QQ客服：3257982914

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