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  • 柚木柯因

    Tectochrysin

    柚木柯因
    产品编号 CFN98840
    CAS编号 520-28-5
    分子式 = 分子量 C16H12O4 = 268.3
    产品纯度 >=98%
    物理属性 Yellow cryst.
    化合物类型 Flavonoids
    植物来源 The heartwoods of Pinus strobus L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    柚木柯因 CFN98840 520-28-5 10mg QQ客服:215959384
    柚木柯因 CFN98840 520-28-5 20mg QQ客服:215959384
    柚木柯因 CFN98840 520-28-5 50mg QQ客服:215959384
    柚木柯因 CFN98840 520-28-5 100mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Georgia Institute of Technology (USA)
  • Tohoku University (Japan)
  • Universitas Airlangga (Indonesia)
  • Rio de Janeiro State University (Brazil)
  • University of Lodz (Poland)
  • Shanghai University of TCM (China)
  • Amity University (India)
  • National Chung Hsing University (Taiwan)
  • University of Brasilia (Brazil)
  • Helmholtz Zentrum München (Germany)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • University of Toulouse (France)
  • The Institute of Cancer Research (United Kingdom)
  • Sanford Burnham Medical Research Institute (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • BMC Complement Altern Med.2014, 14:352
  • Mol Med Rep.2014, 9(5):1653-9
  • J-STAGE2015, 249-255
  • Appl Microbiol Biotechnol.2016, 100(9):3965-77
  • Food Research International2016, 106-113
  • Onco Targets Ther.2017, 10:3467-3474
  • J Ethnopharmacol.2017, 198:87-90
  • University of Central Lancashire2017, 20472
  • Korean J of Food Science&Technology 2017, 49(2):146-150
  • Front Pharmacol.2017, 8:205
  • Molecules.2018, 23(2)
  • Cell Biochem Funct.2018, 36(6):303-311
  • Biofactors.2018, 44(2):168-179
  • Biochem Biophys Res Commun.2018, 505(4):1148-1153
  • Front Pharmacol.2019, 10:1025
  • Cancer Manag Res.2019, 11:483-500
  • Plant Physiol Biochem.2019, 144:355-364
  • Molecules.2019, 24(21):E3834
  • Phytother Res.2019, 33(7):1784-1793
  • The Malaysian journal of pathology2019, 41(3):243-251
  • Ann Transl Med.2019, 7(23):731
  • Oxid Med Cell Longev2020, 12
  • Plant Growth Regulation2020, 90(2):383-392
  • ...
  • 生物活性
    Description: Tectochrysin is a promising inhibitor for the reversal of ABCG2-mediated drug transport, it leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation.Tectochrysin has antioxidant effect, it also exhibits a significant hepatoprotective activity in hepatic damage induced by CCl4-intoxication in rats.
    Targets: STAT | Caspase | Bcl-2/Bax | ATPase
    In vivo:
    Arch Pharm Res. 2003 Jan;26(1):43-6.
    In vivo anti-oxidant activities of tectochrysin.[Pubmed: 12568357]
    The anti-oxidant activities of tectochrysin, a major compound of propolis, were investigated.
    METHODS AND RESULTS:
    Tectochrysin exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by CCl4-intoxication in rats. Tectochrysin tested exhibited a lipid peroxidation causing a significant decrease in MDA production in TBA-reactant assay. Tectochrysin was strong in the increase in the anti-oxidant enzymes such as hepatic cytosolic superoxide dismutase, catalase and glutathione peroxidase activities in CCl4-intoxicated rats.
    CONCLUSIONS:
    These results suggest that tectochrysin possess not only the anti-oxidant, but also the activities in CCl4-intoxicated rats. Especially, tectochrysin was found to cause significant increases in the rat liver cytosolic SOD, catalase, GSH-px activities as well as a significant decrease in the MDA production.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.7272 mL 18.6359 mL 37.2717 mL 74.5434 mL 93.1793 mL
    5 mM 0.7454 mL 3.7272 mL 7.4543 mL 14.9087 mL 18.6359 mL
    10 mM 0.3727 mL 1.8636 mL 3.7272 mL 7.4543 mL 9.3179 mL
    50 mM 0.0745 mL 0.3727 mL 0.7454 mL 1.4909 mL 1.8636 mL
    100 mM 0.0373 mL 0.1864 mL 0.3727 mL 0.7454 mL 0.9318 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    7-甲醚黄芩素; Negletein CFN91886 29550-13-8 C16H12O5 = 284.26 5mg QQ客服:3257982914
    荠苧黄酮; Mosloflavone CFN90893 740-33-0 C17H14O5 = 298.3 20mg QQ客服:2159513211
    6-羟基汉黄芩素; 6-Hydroxywogonin CFN95009 76844-70-7 C16H12O6 = 300.3 5mg QQ客服:1413575084
    5,7-二羟基-6,8-二甲氧基黄酮; 6-Methoxywogonin CFN98403 3162-45-6 C17H14O6 = 314.3 5mg QQ客服:1148253675
    6,7-二羟基黄酮; 6,7-Dihydroxyflavone CFN70351 38183-04-9 C15H10O4 = 254.2 5mg QQ客服:215959384
    7,8-二羟基黄酮; 7,8-Dihydroxyflavone CFN96512 38183-03-8 C15H10O4 = 254.24 20mg QQ客服:2932563308
    白杨素; Chrysin CFN98741 480-40-0 C15H10O4 = 254.2 20mg QQ客服:1148253675
    5-羟基-7-乙酰氧基黄酮; 5-Hydroxy-7-acetoxyflavone CFN97139 6674-40-4 C17H12O5 = 296.3 5mg QQ客服:1413575084
    5-乙酰氧基-7-羟基黄酮; 5-Acetoxy-7-hydroxyflavone CFN99409 132351-58-7 C17H12O5 = 296.3 5mg QQ客服:1148253675
    5,7-二乙酰氧基黄酮; 5,7-Diacetoxyflavone CFN97138 6665-78-7 C19H14O6 = 338.3 5mg QQ客服:3257982914

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