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  • 伪原皂苷Pa

    Parisyunnanoside B

    伪原皂苷Pa
    产品编号 CFN90704
    CAS编号 945865-37-2
    分子式 = 分子量 C50H80O21 = 1016.0
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The rhizomes of Paris yunnanensis Franch.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    伪原皂苷Pa CFN90704 945865-37-2 1mg QQ客服:2159513211
    伪原皂苷Pa CFN90704 945865-37-2 5mg QQ客服:2159513211
    伪原皂苷Pa CFN90704 945865-37-2 10mg QQ客服:2159513211
    伪原皂苷Pa CFN90704 945865-37-2 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Leipzig (Germany)
  • University of Maryland School of Medicine (USA)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Agricultural Research Organization (ARO) (Israel)
  • Universidad Veracuzana (Mexico)
  • Universidade do Porto (Portugal)
  • University of Beira Interior (Portugal)
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  • National Research Council of Canada (Canada)
  • University of Auckland (New Zealand)
  • Semmelweis Unicersity (Hungary)
  • University of Vienna (Austria)
  • University of Vigo (Spain)
  • University of Virginia (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • British Jou. Med.&Med. Research2014, 1802-1811
  • Industrial Food Engineering2015, 19(4):408-413
  • Phytomedicine.2015, 22(4):498-503
  • J-STAGE2015, 249-255
  • Asian J Beauty Cosmetol2016, 14(3):249-257
  • Current Pharmaceutical Analysis2017, 13(5)
  • Molecules.2017, 22(12)
  • Molecules.2017, 22(6)
  • Oncotarget.2017, 9(3):4161-4172
  • Industrial Crops and Products2017, 95:286-295
  • Food Res Int.2017, 96:40-45
  • PLoS One.2018, 13(11):e0208055
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Molecules.2018, 23(10):E2638
  • Molecules.2018, 23(12):E3103
  • Arch Biochem Biophys.2018, 644:93-99
  • BMC Microbiol.2019, 19(1):78
  • Evid Based Complement Alternat Med.2019, 2019:2135351
  • Molecules.2019, 24(22):E4022
  • J Sep Sci.2019, 42(21):3352-3362
  • Korean Journal of Pharmacognosy.2019, 50(1):65-71
  • J Ethnopharmacol.2020, 249:112396
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Planta Med. 2009 Mar;75(4):356-63.
    Steroidal saponins from the rhizome of Paris polyphylla and their cytotoxic activities.[Pubmed: 19085682 ]
    Two new furostanol saponins and one new spirostanol saponin were isolated from the rhizome of Paris polyphylla Smith var. yunnanensis, together with 18 known steroidal saponins.
    METHODS AND RESULTS:
    The structures of the new steroidal saponins were elucidated as 26-O-beta-D-glucopyranosyl-(25R)-5-ene-furost-3 beta, 17 alpha, 22 alpha, 26-tetrol-3-O-alpha-L-arabinofuranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (2, parisyunnanoside A), 26-O-beta-D-glucopyranosyl-(25R)-5, 20 (22)-diene-furost-3 beta, 26-diol-3-O-alpha-L-arabinofuranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (7, Parisyunnanoside B), and (25R)-spirost-5-ene-3 beta, 12 alpha-diol-3-O-alpha-L-rhamnopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (13, parisyunnanoside C) by MS and 1 D and 2 D NMR analysis. The isolated compounds were evaluated for their cytotoxicity against HL-60 human promyelocytic leukemia cells.
    CONCLUSIONS:
    Our results showed that the spirostanol framework of the aglycone and the terminal alpha-L-rhamnopyranosyl with 1-->2 linkage to the sugar chain of saponins at C-3 are essential for their high cytotoxicity, whereas the hydroxy group substitution at C-12 or C-17 of the aglycone causes a reduction in their activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.9843 mL 4.9213 mL 9.8425 mL 19.685 mL 24.6063 mL
    5 mM 0.1969 mL 0.9843 mL 1.9685 mL 3.937 mL 4.9213 mL
    10 mM 0.0984 mL 0.4921 mL 0.9843 mL 1.9685 mL 2.4606 mL
    50 mM 0.0197 mL 0.0984 mL 0.1969 mL 0.3937 mL 0.4921 mL
    100 mM 0.0098 mL 0.0492 mL 0.0984 mL 0.1969 mL 0.2461 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    原皂苷Pb; Dichotomin CFN90703 53093-47-3 C57H94O26 = 1195.34 5mg QQ客服:1148253675
    知母皂苷B; Anemarsaponin B CFN99532 139051-27-7 C45H74O18 = 903.04 20mg QQ客服:3257982914
    知母皂苷BIII; Anemarsaponin BIII CFN90778 142759-74-8 C45H74O18 = 903.1 5mg QQ客服:3257982914
    知母皂苷C; Timorsaponin C CFN90779 185432-00-2 C45H74O18 = 903.1 5mg QQ客服:2932563308
    伪原皂苷Pa; Parisyunnanoside B CFN90704 945865-37-2 C50H80O21 = 1016.0 5mg QQ客服:2932563308
    伪原薯蓣皂苷; Pseudoprotodioscin CFN90694 102115-79-7 C51H82O2 = 1031.18 20mg QQ客服:2159513211
    蒺藜皂苷K; Terrestrosin K CFN90822 193605-07-1 C51H82O24 = 1079.2 10mg QQ客服:2159513211
    伪原皂苷Pb; Pseudoproto Pb CFN90705 102100-46-9 C57H92O25 = 1177.4 5mg QQ客服:2159513211
    新知母皂苷BII; Officinalisinin I CFN90692 57944-18-0 C45H76O19 = 921.07 20mg QQ客服:2932563308
    知母皂苷E; Anemarsaponin E CFN99533 136565-73-6 C46H78O19 = 934.03 10mg QQ客服:3257982914

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