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  • 伪原皂苷Pa

    Parisyunnanoside B

    伪原皂苷Pa
    产品编号 CFN90704
    CAS编号 945865-37-2
    分子式 = 分子量 C50H80O21 = 1016.0
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The rhizomes of Paris yunnanensis Franch.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    伪原皂苷Pa CFN90704 945865-37-2 1mg QQ客服:1413575084
    伪原皂苷Pa CFN90704 945865-37-2 5mg QQ客服:1413575084
    伪原皂苷Pa CFN90704 945865-37-2 10mg QQ客服:1413575084
    伪原皂苷Pa CFN90704 945865-37-2 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Kyushu University (Japan)
  • Georgia Institute of Technology (USA)
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  • University of Brasilia (Brazil)
  • Colorado State University (USA)
  • Uniwersytet Jagielloński w Krakowie (Poland)
  • St. Jude Children Research Hospital (USA)
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  • University of Virginia (USA)
  • Institute of Tropical Disease Universitas Airlangga (Indonesia)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Mol Sci. 2014, 15(5):8443-57
  • The Journal of Internal Korean Medicine2015, 36(4):486-497
  • Mol Cells.2015, 38(9):765-72
  • Sci Rep.2015, 5:13194
  • Ind Crops Prod.2015, 67:185-191
  • Asian J Beauty Cosmetol2016, 14(3):249-257
  • Phytochem Anal.2016, 27(5):296-303
  • Tea Res. Ins. Of China2017, 1-12
  • Molecules.2017, 22(3)
  • Phytomedicine.2017, 24:77-86
  • The Japan Society for Analytical Chemistry2017, 613-617
  • Journal of Analytical Chemistry2017, 854-861
  • Mol Pharm.2018, 15(8):3285-3296
  • Evid Based Complement Alternat Med.2018, 2018:4580627
  • Biosci Rep.2018, 38(4)
  • J Pharm Biomed Anal.2019, 172:268-277
  • Int J Mol Sci.2019, 20(23):E6071
  • Molecules.2019, 25(1):E103
  • Int J Mol Med.2019, 43(6):2516-2522
  • Biomolecules.2019, 9(11):E696
  • LWT-Food Sci Technol2020, 109163
  • Drug Des Devel Ther.2020, 14:61-71
  • J Mol Recognit.2020, 33(2):e2819
  • ...
  • 生物活性
    Description: Reference standards.
    In vitro:
    Planta Med. 2009 Mar;75(4):356-63.
    Steroidal saponins from the rhizome of Paris polyphylla and their cytotoxic activities.[Pubmed: 19085682 ]
    Two new furostanol saponins and one new spirostanol saponin were isolated from the rhizome of Paris polyphylla Smith var. yunnanensis, together with 18 known steroidal saponins.
    METHODS AND RESULTS:
    The structures of the new steroidal saponins were elucidated as 26-O-beta-D-glucopyranosyl-(25R)-5-ene-furost-3 beta, 17 alpha, 22 alpha, 26-tetrol-3-O-alpha-L-arabinofuranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (2, parisyunnanoside A), 26-O-beta-D-glucopyranosyl-(25R)-5, 20 (22)-diene-furost-3 beta, 26-diol-3-O-alpha-L-arabinofuranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (7, Parisyunnanoside B), and (25R)-spirost-5-ene-3 beta, 12 alpha-diol-3-O-alpha-L-rhamnopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (13, parisyunnanoside C) by MS and 1 D and 2 D NMR analysis. The isolated compounds were evaluated for their cytotoxicity against HL-60 human promyelocytic leukemia cells.
    CONCLUSIONS:
    Our results showed that the spirostanol framework of the aglycone and the terminal alpha-L-rhamnopyranosyl with 1-->2 linkage to the sugar chain of saponins at C-3 are essential for their high cytotoxicity, whereas the hydroxy group substitution at C-12 or C-17 of the aglycone causes a reduction in their activity.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.9843 mL 4.9213 mL 9.8425 mL 19.685 mL 24.6063 mL
    5 mM 0.1969 mL 0.9843 mL 1.9685 mL 3.937 mL 4.9213 mL
    10 mM 0.0984 mL 0.4921 mL 0.9843 mL 1.9685 mL 2.4606 mL
    50 mM 0.0197 mL 0.0984 mL 0.1969 mL 0.3937 mL 0.4921 mL
    100 mM 0.0098 mL 0.0492 mL 0.0984 mL 0.1969 mL 0.2461 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    知母皂苷C; Timorsaponin C CFN90779 185432-00-2 C45H74O18 = 903.1 5mg QQ客服:1413575084
    伪原皂苷Pa; Parisyunnanoside B CFN90704 945865-37-2 C50H80O21 = 1016.0 5mg QQ客服:3257982914
    伪原薯蓣皂苷; Pseudoprotodioscin CFN90694 102115-79-7 C51H82O2 = 1031.18 20mg QQ客服:2932563308
    蒺藜皂苷K; Terrestrosin K CFN90822 193605-07-1 C51H82O24 = 1079.2 10mg QQ客服:2932563308
    伪原皂苷Pb; Pseudoproto Pb CFN90705 102100-46-9 C57H92O25 = 1177.4 5mg QQ客服:2932563308
    新知母皂苷BII; Officinalisinin I CFN90692 57944-18-0 C45H76O19 = 921.07 20mg QQ客服:1148253675
    知母皂苷E; Anemarsaponin E CFN99533 136565-73-6 C46H78O19 = 934.03 10mg QQ客服:2159513211
    原薯蓣皂苷; Protodioscin CFN99517 55056-80-9 C51H84O22 = 1049.21 20mg QQ客服:2159513211
    甲基原薯蓣皂苷; Methyl protodioscin CFN99585 54522-52-0 C52H86O22 = 1063.23 20mg QQ客服:215959384
    原翠雀皂苷; Protodeltonin CFN93008 94992-08-2 C51H84O23 = 1065.21 5mg QQ客服:3257982914

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