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  • 异奥卡宁

    Isookanin

    异奥卡宁
    产品编号 CFN90850
    CAS编号 1036-49-3
    分子式 = 分子量 C15H12O6 = 288.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Flavonoids
    植物来源 The herbs of Bidens pilosa
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    异奥卡宁 CFN90850 1036-49-3 1mg QQ客服:3257982914
    异奥卡宁 CFN90850 1036-49-3 5mg QQ客服:3257982914
    异奥卡宁 CFN90850 1036-49-3 10mg QQ客服:3257982914
    异奥卡宁 CFN90850 1036-49-3 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Pretoria (South Africa)
  • Chungnam National University (Korea)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Nanjing University of Chinese Medicine (China)
  • Sant Gadge Baba Amravati University (India)
  • John Innes Centre (United Kingdom)
  • Seoul National University (Korea)
  • Monash University Malaysia (Malaysia)
  • University of Bonn (Germany)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Amity University (India)
  • Washington State University (USA)
  • University of the Basque Country (Spain)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Faculty of Chem. & Nat. Resource Eng.2014, 62
  • Phytomedicine.2015, 22(11):1027-36
  • Plant Cell,Tissue & Organ Culture2016, 127(1):115-121
  • Free Radic Biol Med.2016, 97:307-319
  • J Chromatogr A.2017, 1518:46-58
  • J of L. Chroma.&Related Tech2017, 252-258
  • Korean j.of Pharm.2017, 70-76
  • Front Plant Sci.2017, 8:723
  • Food Res Int.2018, 106:909-919
  • Evid Based Complement Alternat Med.2018, 2018:3610494
  • Molecules.2018, 23(7):E1659
  • Phytother Res.2018, 32(12):2551-2559
  • Spectrochim Acta A2019, 210:372-380
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • Molecules.2019, 24(2):E343
  • Molecules.2019, 24(6):E1177
  • Exp Biol Med (Maywood).2019, 244(18):1665-1679
  • Saudi Pharm J.2019, 27(1):145-153
  • Journal of Apiculture2019, 34(2):131-136
  • J Mol Histol.2019, 50(4):343-354
  • J Food Sci Technol.2019, 56(5):2712-2720
  • Phytomedicine.2019, 56:48-56
  • Oxid Med Cell Longev2019, 9056845:13
  • ...
  • 生物活性
    Description: Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity, with the IC50 value of 7.9 ± 0.53 uM. Isookanin is a potent inhibitor of α-amylase (IC₅₀=0.447 mg/ml).
    In vitro:
    J Agric Food Chem. 2015 Jan 14;63(1):200-7.
    New phenolic compounds from Coreopsis tinctoria Nutt. and their antioxidant and angiotensin i-converting enzyme inhibitory activities.[Pubmed: 25516207 ]
    Three new phenolic compounds, coretinphenol (1), coretincone (2), and coretinphencone (3), were isolated from the buds of Coreopsis tinctoria Nutt., together with nine known compounds, including butein (4), okanin (5), isoliquiritigenin (6), maritimetin (7), taxifolin (8), Isookanin (9), marein (10), sachalinoside B (11), and 2-phenylethyl-β-d-glucoside (12).
    METHODS AND RESULTS:
    The chemical structures of these compounds were elucidated by extensive spectroscopic analysis and on the basis of their chemical reactivity. This work represents the first recorded example of the isolation of compounds 1–3, 6, 7, 9, 11, and 12 from C. tinctoria. Compounds 5–9 showed strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity, with IC50 values of 3.35 ± 0.45, 9.6 ± 2.32, 4.12 ± 0.21, 6.2 ± 0.43, and 7.9 ± 0.53 μM, respectively. Compounds 2 and 8 exhibited angiotensin I-converting enzyme inhibitory activity, with IC50 values of 228 ± 4.47 and 145.67 ± 3.45 μM, respectively.
    CONCLUSIONS:
    The activities of phenolic compounds isolated from C. tinctoria support the medicinal use of this plant in the prevention of cardiovascular diseases.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4686 mL 17.343 mL 34.6861 mL 69.3722 mL 86.7152 mL
    5 mM 0.6937 mL 3.4686 mL 6.9372 mL 13.8744 mL 17.343 mL
    10 mM 0.3469 mL 1.7343 mL 3.4686 mL 6.9372 mL 8.6715 mL
    50 mM 0.0694 mL 0.3469 mL 0.6937 mL 1.3874 mL 1.7343 mL
    100 mM 0.0347 mL 0.1734 mL 0.3469 mL 0.6937 mL 0.8672 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    橙皮素; Hesperetin CFN98842 520-33-2 C16H14O6 = 302.3 20mg QQ客服:1413575084
    橙皮素-7-甲醚; Hesperetin-7-methyl ether CFN90876 N/A C17H16O6 = 316.3 10mg QQ客服:2932563308
    圣草酚 7,3',4'-三甲醚; 7,3',4'-Tri-O-methyleriodictyol CFN89491 70987-96-1 C18H18O6 = 330.33 5mg QQ客服:2159513211
    异奥卡宁; Isookanin CFN90850 1036-49-3 C15H12O6 = 288.3 10mg QQ客服:1413575084
    黄诺马苷; Flavanomarein CFN91006 577-38-8 C21H22O11 = 450.4 5mg QQ客服:3257982914
    黄苏木素; Plathymenin CFN96496 492-12-6 C15H12O6 = 288.25 5mg QQ客服:1148253675
    圣草酚; Eriodictyol CFN99719 552-58-9 C15H12O6 = 288.25 20mg QQ客服:1413575084
    7-O-甲基圣草酚; 7-O-Methyleriodictyol CFN98833 51857-11-5 C16H14O6 = 302.3 5mg QQ客服:215959384
    高圣草素; Homoeriodictyol CFN96489 446-71-9 C16H14O6 = 302.28 5mg QQ客服:1413575084
    槲寄生新甙III; Viscumneoside III CFN89421 118985-27-6 C27H32O15 = 596.53 10mg QQ客服:2932563308

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