• 中药标准品生产商,产品定制服务
  • 栀子苷

    Gardenoside

    栀子苷
    产品编号 CFN90237
    CAS编号 24512-62-7
    分子式 = 分子量 C17H24O11 = 404.37
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Iridoids
    植物来源 The fruits of Gardenia jasminoides Ellis
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    栀子苷 CFN90237 24512-62-7 10mg QQ客服:2159513211
    栀子苷 CFN90237 24512-62-7 20mg QQ客服:2159513211
    栀子苷 CFN90237 24512-62-7 50mg QQ客服:2159513211
    栀子苷 CFN90237 24512-62-7 100mg QQ客服:2159513211
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Hamdard University (India)
  • John Innes Centre (United Kingdom)
  • Nanjing University of Chinese Medicine (China)
  • Siksha O Anusandhan University (India)
  • University of Bordeaux (France)
  • Kyung Hee University (Korea)
  • The University of Newcastle (Australia)
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Univerzita Karlova v Praze (Czech Republic)
  • Helmholtz Zentrum München (Germany)
  • University of Limpopo (South Africa)
  • MTT Agrifood Research Finland (Finland)
  • Semmelweis Unicersity (Hungary)
  • Universidad de La Salle (Mexico)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Asian Journal of Chemistry2014, 26(22):7811-7816
  • Analytical sci. & Tech2016, 186-193
  • J Med Food.2016, 19(12):1155-1165
  • Tropical J. of Pha. Research2017, 16(3):543-552
  • Exp Parasitol.2017, 183:160-166
  • J Ethnopharmacol.2017, 198:205-213
  • Journal of Life Science2017, 233-240
  • PLoS One.2018, 13(11):e0208055
  • J Pharm Biomed Anal.2018, 151:32-41
  • Journal of Physiology & Pathology in Korean Medicine.2018, 32(2): 106-112
  • Anticancer Res.2018, 38(4):2127-2135
  • Biochem Biophys Res Commun.2018, 505(1):261-266
  • Arch Biochem Biophys.2018, 644:93-99
  • Sci Rep.2018, 8:9267
  • Bio-protocol2018, 9(14):e3301
  • Microb Pathog.2019, 131:128-134
  • Chemistry of Plant Materials.2019, 215-222
  • Phytother Res.2019, 33(3):676-689
  • Anal Sci.2019, 35(12):1317-1325
  • Toxicol In Vitro.2019, 59:161-178
  • Plos One.2019, 15(2):e0220084
  • Sci Rep.2019, 9(1):4646
  • J Sep Sci.2020, 201901140
  • ...
  • 生物活性
    Description: Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB activity. Gardenoside may be considered potential drug candidates that target P2X3 and P2X7 purine receptors.
    Targets: NF-kB | Antifection | MCP-1 | TNF-α | MPO | P2X3 receptor | P2X7 receptor | IL Receptor
    In vivo:
    Chinese Journal of Information on Tcm, 2004, 11(6):500-502.
    Effect of Concha Margatitifera Usta, Cholic Acid, Gardenoside, Baicalin on MCP-1 in the Ischemic Cerebral Tissue of Rats after Middle Cerebral Artery Occlusion.[Reference: WebLink]
    To study the effect of Concha Margatitifera Usta, Cholic Acid, Gardenoside, Baicalin on the protein levels of monocyte chemoattractant protein (MCP-1) in the ischemic cerebral tissue of rats after middle cerebral artery occlusion in rats.
    METHODS AND RESULTS:
    The 110 male SD rats were randomly assigned to the normal group, middle cerebral artery occlusion for 12 hours group and Concha Margatitifera Usta, Cholic Acid, Gardenoside, Baicalin cure middle cerebral artery occlusion for 12 hours group, middle cerebral artery occlusion for 24 hours group and Concha Margatitifera Usta, Cholic Acid, Gardenoside, Baicalin cure middle cerebral artery occlusion for 24 hours group. The protein levels of MCP-1 were measured by enzyme linked immunosorbent assay (ELISA). The protein level of MCP-1 of the ischemic cerebral tissue of rats in the middle cerebral artery occlusion for 12 hours group was markedly increased than the normal group (P0.05). The protein level of MCP-1 of the ischemic cerebral tissue of rats in Concha Margatitifera Usta and Gardenoside cure middle cerebral artery occlusion for 12 hours group were significantly lower than it in the middle cerebral artery occlusion for 12 hours group (P0.01). There was no significant change on the protein level of MCP-1 in the ischemic cerebral tissue of rats between Cholic Acid, Baicalin cure middle cerebral artery occlusion for 12 hours group and the middle cerebral artery occlusion for 12 hours group. The protein level of MCP-1 of the ischemic cerebral tissue of rats in the middle cerebral artery occlusion for 24 hours group was markedly increased than the normal group (P0.05). The protein level of MCP-1 of the ischemic cerebral tissue of rats in the Concha Margatitifera Usta, Cholic Acid, Gardenoside ,Baicalin cure middle cerebral artery occlusion for 24 hours group were significantly lower than it in the middle cerebral artery occlusion for 24 hours group (P0.05 or P0.01).
    CONCLUSIONS:
    Reducing the level of MCP-1 of the ischemic cerebral tissue of rats after ischemia may be one of the most important ways for the neuroprotective effects the middle cerebral artery occlusion group.
    Chinese Veterinary Science, 2013, 43(8):876-880.
    Inhibited effects of gardenoside on the LPS-induced mice mastitis[Reference: WebLink]

    METHODS AND RESULTS:
    To investigate the protective effects of gardenoside on the mice against mastitis,48 male and female mice were paired and randomly divided into 6 groups.Mouse mastitis models were established by pouring LPS into mammary gland after farrowing.Female mice with mastitis were treated with different concentrations of gardenoside(25,50 and 100 mg/kg) and dexamethasone,respectively. Mammary glands of the mice were collected at 24 h after the treatment to study the effects of gardenoside on the histopathology and the expression of myeloperoxidase(MPO),TNF-α,IL-6 and IL-1β. In result,the expression levels of TNF-α,IL-6 and IL-1β were significantly higher in the LPS group than the normal group,indicating the model of mastitis was established successfully in this study.Mammary gland pathological damages were significantly inhibited by gardenoside treatment compared with the LPS group(P0.01).MPO expression levels were decreased with the treatment of low,medium and high doses of gardenoside,and the expression levels of TNF-α,IL-6 and IL-1β were significantly lower in the gardenoside group than the dexamethasone group.
    CONCLUSIONS:
    These results indicated that gardenoside has inhibitory effect on mice mastitis,and the inhibitory effect exhibits a dose-dependent manner.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.473 mL 12.3649 mL 24.7298 mL 49.4597 mL 61.8246 mL
    5 mM 0.4946 mL 2.473 mL 4.946 mL 9.8919 mL 12.3649 mL
    10 mM 0.2473 mL 1.2365 mL 2.473 mL 4.946 mL 6.1825 mL
    50 mM 0.0495 mL 0.2473 mL 0.4946 mL 0.9892 mL 1.2365 mL
    100 mM 0.0247 mL 0.1236 mL 0.2473 mL 0.4946 mL 0.6182 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    戟叶马鞭草苷; Hastatoside CFN96588 50816-24-5 C17H24O11 = 404.37 20mg QQ客服:3257982914
    Griselinoside; Griselinoside CFN97199 71035-06-8 C18H24O12 = 432.4 5mg QQ客服:2159513211
    Garjasmin; Garjasmin CFN99492 144868-43-9 C11H12O5 = 224.2 5mg QQ客服:215959384
    Gardenine; Gardenine CFN99447 139682-36-3 C11H13NO4 = 223.2 5mg QQ客服:3257982914
    栀子苷; Gardenoside CFN90237 24512-62-7 C17H24O11 = 404.37 20mg QQ客服:3257982914
    Splendoside; Splendoside CFN96355 81969-41-7 C17H26O11 = 406.4 5mg QQ客服:215959384
    续断苷A; Dipsanoside A CFN90753 889678-62-0 C66H90O37 = 1475.4 10mg QQ客服:215959384
    续断苷B; Dipsanoside B CFN90754 889678-64-2 C66H90O37 = 1475.4 10mg QQ客服:215959384
    7-去氧-10-羟基马钱苷元; 7-Deoxy-10-hydroxyloganetin CFN89296 76267-48-6 C11H16O5 = 228.24 5mg QQ客服:3257982914
    马钱苷; 番木鳖苷; Loganin CFN99858 18524-94-2 C17H26O10 = 390.4 20mg QQ客服:2932563308

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产