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  • 灵芝酸F

    Ganoderic acid F

    灵芝酸F
    产品编号 CFN92055
    CAS编号 98665-15-7
    分子式 = 分子量 C32H42O9 = 570.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruiting bodys of Ganoderma lucidum
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    灵芝酸F CFN92055 98665-15-7 1mg QQ客服:2159513211
    灵芝酸F CFN92055 98665-15-7 5mg QQ客服:2159513211
    灵芝酸F CFN92055 98665-15-7 10mg QQ客服:2159513211
    灵芝酸F CFN92055 98665-15-7 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Cancer Research Initatives Foundation(CARIF) (Malaysia)
  • Universidade Federal de Goias (UFG) (Brazil)
  • Griffith University (Australia)
  • Tokyo Woman's Christian University (Japan)
  • Semmelweis Unicersity (Hungary)
  • Universidad Industrial de Santander (Colombia)
  • University of Liège (Belgium)
  • Technical University of Denmark (Denmark)
  • Chang Gung University (Taiwan)
  • Kamphaengphet Rajabhat University (Thailand)
  • Universidad de Antioquia (Colombia)
  • Colorado State University (USA)
  • University Medical Center Mainz (Germany)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Industrial Food Engineering2015, 19(4):408-413
  • Phytochemistry Letters2015, 243-247
  • Int. J. of Pha. and Phy. Res.2015, 7(1):144-149
  • J Ethnopharmacol.2016, 192:370-381
  • Chem Biol Interact.2016, 258:59-68
  • Phytother Res.2016, 30(12):2020-2026
  • Sci Rep. 2017, 12953(7)
  • Tropical J. of Pha. Research2017, 16(3):543-552
  • Int. Conference on Med. Sci. and Bio.2017, 17973
  • Int J Mol Sci.2017, 18(12)
  • Universidade Estadual Paulista2017, 42785
  • Cell Physiol Biochem.2017, 43(4):1425-1435
  • Fitoterapia.2018, 124:92-102
  • Microchemical Journal2018, 137:168-173
  • Molecules.2018, 23(11):E2837
  • Korean J Environ Agric.2018, 37(4):260-267
  • Phytomedicine.2018, 38:12-23
  • Biochem Biophys Res Commun.2018, 505(1):261-266
  • J Agric Food Chem.2018, 66(1):351-358
  • Cancer Manag Res.2019, 11:483-500
  • Drug Invention Today2019, 12(6):1303-1306
  • Process Biochemistry2019, 87:213-220
  • Sci Rep.2019, 9:12132
  • ...
  • 生物活性
    Description: Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.
    Targets: HBV | Immunology & Inflammation related
    In vivo:
    Evid Based Complement Alternat Med. 2012;2012:780892.
    Pharmacokinetics of ganoderic acids a and f after oral administration of ling zhi preparation in healthy male volunteers.[Pubmed: 22577465]
    The objectives of this paper were to evaluate the pharmacokinetics of ganoderic acid A and Ganoderic acid F after a single oral dose of the water extract of MG2-strain Ling Zhi (MG2FB-WE) and to assess the influence of food on the pharmacokinetics in 12 healthy male volunteers.
    METHODS AND RESULTS:
    This study was a single-dose, open-label, randomized, two-phase crossover study with at least 2 wk washout period. Each subject was randomly assigned to receive a single oral dose of 3,000 mg of MG2FB-WE in granular formulation dissolved in 200 mL of warm water, either under a fasting condition, or immediately after a standard breakfast (fed condition). Blood samples were collected immediately before and at specific time points until 8 h after MG2FB-WE administration. Plasma ganoderic acid A and Ganoderic acid F concentrations were determined by using liquid chromatography-mass spectrometry (LC-MS) technique.
    CONCLUSIONS:
    In conclusion, the pharmacokinetic profile of both ganoderic acids under a fasting condition was characterized by rapid absorption from the gastrointestinal tract (T(max) at approximately 30 min) and a short elimination half-life (<40 min). Food significantly decreased C(max) and delayed T(max), but did not affect the extent of ganoderic acid A absorption. However, concomitant food intake markedly impeded both rate and extent of Ganoderic acid F absorption.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7522 mL 8.7612 mL 17.5223 mL 35.0447 mL 43.8059 mL
    5 mM 0.3504 mL 1.7522 mL 3.5045 mL 7.0089 mL 8.7612 mL
    10 mM 0.1752 mL 0.8761 mL 1.7522 mL 3.5045 mL 4.3806 mL
    50 mM 0.035 mL 0.1752 mL 0.3504 mL 0.7009 mL 0.8761 mL
    100 mM 0.0175 mL 0.0876 mL 0.1752 mL 0.3504 mL 0.4381 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    灵芝酸K; Ganoderic acid K CFN92057 104700-95-0 C32H46O9 = 574.7 5mg QQ客服:1413575084
    灵芝酸C6; Ganoderic acid C6 CFN92290 105742-76-5 C30H42O8 = 530.7 10mg QQ客服:2932563308
    灵芝酸C6甲酯; Methyl ganoderate C6 CFN92292 105742-81-2 C31H44O8 = 544.7 5mg QQ客服:2159513211
    灵芝酸H; Ganoderic acid H CFN92056 98665-19-1 C32H44O9 = 572.7 5mg QQ客服:1413575084
    灵芝酸H甲酯; Methyl ganoderate H CFN92291 98665-11-3 C33H46O9 = 586.7 5mg QQ客服:3257982914
    去乙酰基灵芝酸F; Deacetyl ganoderic acid F CFN90746 100665-44-9 C30H40O8 = 528.6 5mg QQ客服:2159513211
    灵芝酸F; Ganoderic acid F CFN92055 98665-15-7 C32H42O9 = 570.7 5mg QQ客服:215959384

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