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  • Desoxygambogenin

    Desoxygambogenin

    Desoxygambogenin
    产品编号 CFN92088
    CAS编号 173614-93-2
    分子式 = 分子量 C38H48O6 = 600.8
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Miscellaneous
    植物来源 The herbs of Garcinia hanburyi Hook. f.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    Desoxygambogenin CFN92088 173614-93-2 1mg QQ客服:1413575084
    Desoxygambogenin CFN92088 173614-93-2 5mg QQ客服:1413575084
    Desoxygambogenin CFN92088 173614-93-2 10mg QQ客服:1413575084
    Desoxygambogenin CFN92088 173614-93-2 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Hawaii Cancer Center (USA)
  • Universidad Veracuzana (Mexico)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Rio de Janeiro State University (Brazil)
  • University of Zurich (Switzerland)
  • Ain Shams University (Egypt)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • University of Melbourne (Australia)
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  • Georgia Institute of Technology (USA)
  • National Chung Hsing University (Taiwan)
  • Biotech R&D Institute (USA)
  • Subang Jaya Medical Centre (Malaysia)
  • Donald Danforth Plant Science Center (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Molecules. 2013, 18(7):7376-88
  • Tumour Biol.2015, 36(9):7027-34
  • Appl Microbiol Biotechnol.2016, 100(9):3965-77
  • Org Biomol Chem.2017, 15(31):6483-6492
  • FEMS Microbiol Lett.2017, 364(11)
  • Arch Toxicol.2017, 91(10):3225-3245
  • Nutrients.2018, 10(10)
  • Molecules.2018, 23(9):E2121
  • Food Chem.2018, 252:207-214
  • Cell Biochem Funct.2018, 36(6):303-311
  • Phytomedicine.2018, 41:62-66
  • J Herbmed Pharmacol.2018, 7(4):280-286
  • Virulence.2018, 9(1):588-603
  • World J Mens Health.2019, 10.5534
  • Drug Invention Today2019, 12(6):1303-1306
  • Postharvest Biol Tec2019, 149:18-26
  • Cardiovasc Toxicol.2019, 19(4):297-305
  • Molecules.2019, 24(11):E2044
  • FASEB J.2019, 33(8):9685-9694
  • J Agric Food Chem.2019, 67(27):7748-7754
  • Food Sci Nutr.2019, 8(1):246-256
  • Plos One.2020, 10.1371
  • Plant Growth Regulation2020, 90(2):383-392
  • ...
  • 生物活性
    Description: Desoxygambogenin is a cytotoxic xanthone, it has anti-HIV-1 activity.
    Targets: HIV
    In vitro:
    Planta Med. 2007 Jan;73(1):33-40. Epub 2006 Nov 21.
    Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi.[Pubmed: 17117343]
    Three new caged xanthones, 7-methoxydesoxymorellin (1), 2-isoprenylforbesione (2) and 8,8a-epoxymorellic acid (3), together with nine known caged xanthones were isolated from the EtOAc extracts of resin and fruits of Garcinia hanburyi.
    METHODS AND RESULTS:
    The structures were determined by spectroscopic methods. Most of the isolated compounds showed significant cytotoxicities against a panel of mammalian cancer cell lines. Compound 3, together with the known compounds desoxymorellin, morellic acid, gambogic acid, hanburin, forbesione and dihydroisomorellin, exhibited anti-HIV-1 activity in the reverse transcriptase (RT) assay while the known compounds Desoxygambogenin and dihydroisomorellin were found moderately active in the syncytium assay.
    CONCLUSIONS:
    This work represents the first report on the anti-HIV-1 activities of caged xanthones.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6644 mL 8.3222 mL 16.6445 mL 33.2889 mL 41.6112 mL
    5 mM 0.3329 mL 1.6644 mL 3.3289 mL 6.6578 mL 8.3222 mL
    10 mM 0.1664 mL 0.8322 mL 1.6644 mL 3.3289 mL 4.1611 mL
    50 mM 0.0333 mL 0.1664 mL 0.3329 mL 0.6658 mL 0.8322 mL
    100 mM 0.0166 mL 0.0832 mL 0.1664 mL 0.3329 mL 0.4161 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Isogambogenin; Isogambogenin CFN92086 173938-23-3 C38H46O7 = 614.8 5mg QQ客服:2159513211
    Desoxygambogenin; Desoxygambogenin CFN92088 173614-93-2 C38H48O6 = 600.8 5mg QQ客服:215959384
    异新藤黄酸; Isogambogenic acid CFN92096 887923-47-9 C38H46O8 = 630.8 5mg QQ客服:2159513211
    新藤黄酸; Gambogenic acid CFN92097 173932-75-7 C38H46O8 = 630.8 10mg QQ客服:1148253675
    藤黄酸; Gambogic acid CFN90172 2752-65-0 C38H44O8 = 628.75 20mg QQ客服:1413575084
    新藤黄酸; Neogambogic acid CFN90175 93772-31-7 C38H46O9 = 646.77 20mg QQ客服:215959384
    Gambogin; Gambogin CFN92089 173792-67-1 C38H46O6 = 598.8 5mg QQ客服:2932563308
    异藤黄酸; Isogambogic acid CFN92098 149655-52-7 C38H44O8 = 628.8 5mg QQ客服:215959384
    9R-10alpha-羟基表藤黄酸; 9R-10alpha-Hydroxyepigambogic acid CFN92099 1097882-33-1 C38H46O9 = 646.8 5mg QQ客服:1413575084
    9S-10alpha-羟基表藤黄酸; 9S-10alpha-Hydroxyepigambogic acid CFN92100 1164201-85-7 C38H46O9 = 646.8 5mg QQ客服:2932563308

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