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  • 6α-羟基猪苓酸C

    6alpha-Hydroxypolyporenic acid C

    6α-羟基猪苓酸C
    产品编号 CFN92741
    CAS编号 24513-63-1
    分子式 = 分子量 C31H46O5 = 498.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Wolfiporia cocos (Schw.) Ryv.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    6α-羟基猪苓酸C CFN92741 24513-63-1 1mg QQ客服:2159513211
    6α-羟基猪苓酸C CFN92741 24513-63-1 5mg QQ客服:2159513211
    6α-羟基猪苓酸C CFN92741 24513-63-1 10mg QQ客服:2159513211
    6α-羟基猪苓酸C CFN92741 24513-63-1 20mg QQ客服:2159513211
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Martin Luther University of Halle-Wittenberg (Germany)
  • Universidade Federal de Santa Catarina (Brazil)
  • St. Jude Children Research Hospital (USA)
  • University of Liège (Belgium)
  • Georgia Institute of Technology (USA)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Max Rubner-Institut (MRI) (Germany)
  • University of Malaya (Malaysia)
  • Stanford University (USA)
  • Universit?t Basel (Switzerland)
  • Utah State University (USA)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Melbourne University (Australia)
  • University of Cincinnati (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Inflammation2015, 38(1):445-55
  • Food Research International2016, 106-113
  • Chemistr of plant2016, 2016021195
  • Phytomedicine.2016, 23(4):331-9
  • Polytechnic University of Catalonia2017, 105826
  • Sci Rep. 2017, 12953(7)
  • J Hematol Oncol.2018, 11(1):112
  • Microchemical Journal2018, 137:168-173
  • Biofactors.2018, 44(2):168-179
  • Toxicol In Vitro.2018, 52:94-105
  • Eur J Pharmacol.2018, 832:96-103
  • J of Essential Oil Research2019, 1677272
  • Molecules.2019, 24(2):329
  • Phytother Res.2019, 33(3):676-689
  • Int J Immunopathol Pharmacol.2019, 33:2058738419857537
  • Academic J of Second Military Medical University2019, 40(1)
  • Journal of Functional Foods2019, 52:430-441
  • J Nat Prod.2019, 82(4):1002-1008
  • TCI CO.2019, US20190151257A1
  • Plant Foods Hum Nutr.2020, 10.1007
  • Food Funct.2020, 10.1039
  • Molecules.2020, 25(3):734
  • Antioxidants (Basel).2020, 9(2):E120
  • ...
  • 生物活性
    Description: 6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv.
    In vitro:
    Zhongguo Zhong Yao Za Zhi. 2008 Jul;33(13):1596-601.
    Absorption of triterpenoid compounds from Indian bread (Poria cocos) across human intestinal epithelial (Caco-2) cells in vitro.[Pubmed: 18837324]
    To study the absorption of 3-epidehydrotumulosic acid (EDHTA), polyporenic acid C (PPAC) and 6alpha-Hydroxypolyporenic acid C (HPPA) isolated from the sclerotium of Poria cocos. In human intestinal epithelial.
    METHODS AND RESULTS:
    By using Caco-2 (the human colonic adenocarcinoma cell lines) cells monolayer as an intestinal epithelial cell model, the permeability of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were studied from apical side (AP side) to basolateral side (BL side) or from BL side to AP side.The P(app) values of EDHTA and PPAC were at a nearly same magnitude with those of propranolol, and 6alpha-Hydroxypolyporenic acid C lied between those of propranolol and atenolol. On the other hand, the efflux transport of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were higher 1.78, 1.91 and 2. 47 times more than its influx transport with 0.56, 0.52 and 0.41 rate of P(app A --> B)/P(app (B --> A).
    CONCLUSIONS:
    EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C can be absorbed across intestinal epithelial cells, among EDHTA and PPAC will be completely. 6alpha-Hydroxypolyporenic acid C will be moderately absorbed compounds. EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C may have been involved in efflux mechanism in Caco-2 cells monolayers model from the basolateral-to-apical direction.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0052 mL 10.0261 mL 20.0521 mL 40.1043 mL 50.1303 mL
    5 mM 0.401 mL 2.0052 mL 4.0104 mL 8.0209 mL 10.0261 mL
    10 mM 0.2005 mL 1.0026 mL 2.0052 mL 4.0104 mL 5.013 mL
    50 mM 0.0401 mL 0.2005 mL 0.401 mL 0.8021 mL 1.0026 mL
    100 mM 0.0201 mL 0.1003 mL 0.2005 mL 0.401 mL 0.5013 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    去氢土莫酸; Dehydrotumulosic acid CFN92837 6754-16-1 C31H48O4 = 484.7 5mg QQ客服:215959384
    去氢茯苓酸; Dehydropachymic acid CFN92742 77012-31-8 C33H50O5 = 526.8 10 mg QQ客服:3257982914
    3-表去氢土莫酸; 3-Epidehydrotumulosic acid CFN92743 167775-54-4 C31H48O4 = 484.7 5mg QQ客服:2932563308
    3-表去氢茯苓酸; 3-Epidehydropachymic acid CFN92738 168293-15-0 C33H50O5 = 526.8 5mg QQ客服:215959384
    过氧去氢土莫酸; Peroxydehydrotumulosic acid CFN92836 943225-53-4 C31H46O6 = 514.7 5mg QQ客服:2159513211
    多孔菌酸C; Polyporenic acid C CFN92739 465-18-9 C31H46O4 = 482.7 5mg QQ客服:1148253675
    16-O-Acetylpolyporenic acid C; 16-O-Acetylpolyporenic acid C CFN96159 2535-06-0 C33H48O5 = 524.7 5mg QQ客服:2932563308
    6α-羟基猪苓酸C; 6alpha-Hydroxypolyporenic acid C CFN92741 24513-63-1 C31H46O5 = 498.7 5mg QQ客服:1148253675
    茯苓新酸A; Poricoic acid A(F) CFN92838 137551-38-3 C31H46O5 = 498.7 10mg QQ客服:3257982914
    Poricoic acid AE ; Poricoic acid AE CFN96980 1159753-88-4 C33H50O5 = 526.75 5mg QQ客服:215959384

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