6α-羟基猪苓酸C

6alpha-Hydroxypolyporenic acid C

	产品编号	CFN92741
	CAS编号	24513-63-1
	分子式 = 分子量	C₃₁H₄₆O₅ = 498.7
	产品纯度	>=98%
	物理属性	Powder
	化合物类型	Triterpenoids
	植物来源	The roots of Wolfiporia cocos (Schw.) Ryv.
ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用

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产品名称	产品编号	CAS编号	包装	QQ客服
6α-羟基猪苓酸C	CFN92741	24513-63-1	1mg	QQ客服：1457312923
6α-羟基猪苓酸C	CFN92741	24513-63-1	5mg	QQ客服：1457312923
6α-羟基猪苓酸C	CFN92741	24513-63-1	10mg	QQ客服：1457312923
6α-羟基猪苓酸C	CFN92741	24513-63-1	20mg	QQ客服：1457312923

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ChemFaces的产品在许多优秀和顶级科学期刊中被引用

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
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PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089

Monash University Sunway Campus (Malaysia)

Funda??o Universitária de Desenvolvimento (Brazil)

Amity University (India)

Griffith University (Australia)

Worcester Polytechnic Institute (USA)

Korea Intitute of Science and Technology (KIST) (Korea)

Universidad de Antioquia (Colombia)

John Innes Centre (United Kingdom)

University of Wisconsin-Madison (USA)

Universiti Sains Malaysia (Malaysia)

Shanghai University of TCM (China)

Universidade Federal de Goias (UFG) (Brazil)

Biotech R&D Institute (USA)

University of Amsterdam (Netherlands)

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Description:

6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv.

In vitro:

Zhongguo Zhong Yao Za Zhi. 2008 Jul;33(13):1596-601.

Absorption of triterpenoid compounds from Indian bread (Poria cocos) across human intestinal epithelial (Caco-2) cells in vitro.[Pubmed: 18837324]

To study the absorption of 3-epidehydrotumulosic acid (EDHTA), polyporenic acid C (PPAC) and 6alpha-Hydroxypolyporenic acid C (HPPA) isolated from the sclerotium of Poria cocos. In human intestinal epithelial.
METHODS AND RESULTS:
By using Caco-2 (the human colonic adenocarcinoma cell lines) cells monolayer as an intestinal epithelial cell model, the permeability of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were studied from apical side (AP side) to basolateral side (BL side) or from BL side to AP side.The P(app) values of EDHTA and PPAC were at a nearly same magnitude with those of propranolol, and 6alpha-Hydroxypolyporenic acid C lied between those of propranolol and atenolol. On the other hand, the efflux transport of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were higher 1.78, 1.91 and 2. 47 times more than its influx transport with 0.56, 0.52 and 0.41 rate of P(app A --> B)/P(app (B --> A).
CONCLUSIONS:
EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C can be absorbed across intestinal epithelial cells, among EDHTA and PPAC will be completely. 6alpha-Hydroxypolyporenic acid C will be moderately absorbed compounds. EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C may have been involved in efflux mechanism in Caco-2 cells monolayers model from the basolateral-to-apical direction.

产品名称	产品编号	CAS编号	分子式 = 分子量	位单	联系QQ
3-表去氢土莫酸; 3-Epidehydrotumulosic acid	CFN92743	167775-54-4	C₃₁H₄₈O₄ = 484.7	5mg	QQ客服：2056216494
3-表去氢茯苓酸; 3-Epidehydropachymic acid	CFN92738	168293-15-0	C₃₃H₅₀O₅ = 526.8	5mg	QQ客服：1413575084
6alpha-羟基去氢茯苓酸; 6alpha-Hydroxydehydropachymic acid	CFN95412	176390-67-3	C₃₃H₅₀O₆ = 542.8	5mg	QQ客服：1413575084
过氧去氢土莫酸; Peroxydehydrotumulosic acid	CFN92836	943225-53-4	C₃₁H₄₆O₆ = 514.7	5mg	QQ客服：2159513211
多孔菌酸C; Polyporenic acid C	CFN92739	465-18-9	C₃₁H₄₆O₄ = 482.7	10mg	QQ客服：1457312923
16-O-Acetylpolyporenic acid C; 16-O-Acetylpolyporenic acid C	CFN96159	2535-06-0	C₃₃H₄₈O₅ = 524.7	5mg	QQ客服：1413575084
6α-羟基猪苓酸C; 6alpha-Hydroxypolyporenic acid C	CFN92741	24513-63-1	C₃₁H₄₆O₅ = 498.7	5mg	QQ客服：215959384
新化合物15; New compound 15	CFN95413	N/A	C₃₁H₄₆O₆ = 514.7	5mg	QQ客服：3257982914
茯苓新酸A; Poricoic acid A(F)	CFN92838	137551-38-3	C₃₁H₄₆O₅ = 498.7	20mg	QQ客服：1413575084
茯苓酸AM; Poricoic acid AM	CFN91538	151200-92-9	C₃₂H₄₈O₅ = 512.7	5mg	QQ客服：1457312923

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	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.0052 mL	10.0261 mL	20.0521 mL	40.1043 mL	50.1303 mL
5 mM	0.401 mL	2.0052 mL	4.0104 mL	8.0209 mL	10.0261 mL
10 mM	0.2005 mL	1.0026 mL	2.0052 mL	4.0104 mL	5.013 mL
50 mM	0.0401 mL	0.2005 mL	0.401 mL	0.8021 mL	1.0026 mL
100 mM	0.0201 mL	0.1003 mL	0.2005 mL	0.401 mL	0.5013 mL