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  • 过氧去氢土莫酸

    Peroxydehydrotumulosic acid

    过氧去氢土莫酸
    产品编号 CFN92836
    CAS编号 943225-53-4
    分子式 = 分子量 C31H46O6 = 514.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The roots of Wolfiporia cocos (Schw.) Ryv.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    过氧去氢土莫酸 CFN92836 943225-53-4 1mg QQ客服:215959384
    过氧去氢土莫酸 CFN92836 943225-53-4 5mg QQ客服:215959384
    过氧去氢土莫酸 CFN92836 943225-53-4 10mg QQ客服:215959384
    过氧去氢土莫酸 CFN92836 943225-53-4 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Charles University in Prague (Czech Republic)
  • Kyushu University (Japan)
  • Srinakharinwirot University (Thailand)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Korea Institute of Oriental Medicine (Korea)
  • University of Brasilia (Brazil)
  • University of Bonn (Germany)
  • The Ohio State University (USA)
  • Universidad Miguel Hernández (Spain)
  • National Hellenic Research Foundation (Greece)
  • Medical University of South Carolina (USA)
  • Univerzita Karlova v Praze (Czech Republic)
  • John Innes Centre (United Kingdom)
  • Institute of Pathophysiology Medical University of Vienna (Austria)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Nat Prod Sci.2014, 20(3):182-190
  • Phytomedicine.2015, 22(4):498-503
  • J Ethnopharmacol.2016, 192:370-381
  • Nutrients.2017, 10(1)
  • Biochem Systematics and Ecology2017, 11-18
  • Molecular & Cellular Toxicology2017, 13(3):271-278
  • Universite de Bordeaux2017, 2017BORD0867
  • Molecules.2017, 22(3)
  • Korean j.of Pharm.2017, 70-76
  • Microchemical Journal2018, 137:168-173
  • Yakugaku Zasshi.2018, 138(4):571-579
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • J Cell Mol Med.2018, 22(9):4236-4242
  • J Sep Sci.2018, 41(7):1682-1690
  • Virulence.2018, 9(1):588-603
  • Wageningen University & Research2018, January 2018
  • Nutrients.2019, 12(1)
  • Food Engineering Progress2019, 23(3)209-216
  • J Ethnopharmacol.2019, 241:112025
  • Toxicol In Vitro.2019, 59:161-178
  • Appl. Sci.2020, 10,1304
  • LWT-Food Sci Technol2020, 109163
  • Cell Metab.2020, S1550-4131(20)30002-4
  • ...
  • 生物活性
    Description: 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells.
    In vitro:
    J Nat Prod. 2007 Jun;70(6):948-53. Epub 2007 May 9.
    Triterpene acids from Poria cocos and their anti-tumor-promoting effects.[Pubmed: 17488130 ]
    The structures of six new lanostane-type triterpene acids isolated from the epidermis of the sclerotia of Poria cocos were established to be 15alpha-hydroxydehydrotumulosic acid (5), 16alpha,25-dihydroxydehydroeburicoic acid (9), 5alpha,8alpha-Peroxydehydrotumulosic acid (10), 25-hydroxyporicoic acid H (11), 16-deoxyporicoic acid B (12), and poricoic acid CM (16) on the basis of spectroscopic methods.
    METHODS AND RESULTS:
    On evaluation of these six and 11 other known triterpene acids isolated from the sclerotium, 1-4, 6-8, 13-15, and 17, against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, all of the compounds except for 1, 3, 4, and 8 exhibited inhibitory effects with IC50 values of 195-340 mol ratio/32 pmol TPA. Compound 12 and poricoic acid C (13) exhibited inhibitory effects on skin tumor promotion in an in vivo two-stage carcinogenesis test using 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9429 mL 9.7144 mL 19.4288 mL 38.8576 mL 48.572 mL
    5 mM 0.3886 mL 1.9429 mL 3.8858 mL 7.7715 mL 9.7144 mL
    10 mM 0.1943 mL 0.9714 mL 1.9429 mL 3.8858 mL 4.8572 mL
    50 mM 0.0389 mL 0.1943 mL 0.3886 mL 0.7772 mL 0.9714 mL
    100 mM 0.0194 mL 0.0971 mL 0.1943 mL 0.3886 mL 0.4857 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    过氧去氢土莫酸; Peroxydehydrotumulosic acid CFN92836 943225-53-4 C31H46O6 = 514.7 5mg QQ客服:215959384
    多孔菌酸C; Polyporenic acid C CFN92739 465-18-9 C31H46O4 = 482.7 5mg QQ客服:2159513211
    16-O-Acetylpolyporenic acid C; 16-O-Acetylpolyporenic acid C CFN96159 2535-06-0 C33H48O5 = 524.7 5mg QQ客服:3257982914
    6α-羟基猪苓酸C; 6alpha-Hydroxypolyporenic acid C CFN92741 24513-63-1 C31H46O5 = 498.7 5mg QQ客服:1148253675
    茯苓新酸A; Poricoic acid A(F) CFN92838 137551-38-3 C31H46O5 = 498.7 10mg QQ客服:215959384
    Poricoic acid AE ; Poricoic acid AE CFN96980 1159753-88-4 C33H50O5 = 526.75 5mg QQ客服:3257982914
    24(31)-Dehydrocarboxyacetylquercinic acid; 24(31)-Dehydrocarboxyacetylquercinic acid CFN96179 127970-62-1 C34H50O7 = 570.8 5mg QQ客服:2932563308
    齿孔酸; 齿孔菌酸; Eburicoic acid CFN90414 560-66-7 C31H50O3 = 470.73 5mg QQ客服:2159513211
    茯苓酸; 茯灵酸; Pachymic acid CFN99590 29070-92-6 C33H52O5 = 528.76 20mg QQ客服:2932563308
    二氢齿孔酸; Dehydroeburicoic acid CFN92740 6879-05-6 C31H48O3 = 468.7 10mg QQ客服:2932563308

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