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  • 4,9-二甲氧基铁屎米酮

    4,9-Dimethoxycanthin-6-one

    4,9-二甲氧基铁屎米酮
    产品编号 CFN92128
    CAS编号 1270001-72-3
    分子式 = 分子量 C16H12N2O3 = 280.3
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Alkaloids
    植物来源 The barks of Ailanthus altissima
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    4,9-二甲氧基铁屎米酮 CFN92128 1270001-72-3 1mg QQ客服:1413575084
    4,9-二甲氧基铁屎米酮 CFN92128 1270001-72-3 5mg QQ客服:1413575084
    4,9-二甲氧基铁屎米酮 CFN92128 1270001-72-3 10mg QQ客服:1413575084
    4,9-二甲氧基铁屎米酮 CFN92128 1270001-72-3 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Acta Agriculturae Scandinavica2015, 381-383
  • Evid Based Complement Alternat Med.2017, 2017:1401279
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  • Journal of Analytical Chemistry2017, 854-861
  • Oncotarget.2017, 9(3):4161-4172
  • Drug Test Anal.2018, 10(10):1579-1589
  • BMC Plant Biol.2018, 18(1):122
  • Molecules.2018, 23(11):E2837
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  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • Industrial Crops and Products2018, 353-362
  • J Liq Chromatogr R T2018, 41(12):761-769
  • J of Physics Conference Series2019, 1349(1)
  • Postharvest Biol Tec2019, 149:18-26
  • Molecules.2019, 24(2):329
  • Molecules.2019, 24(20):3755
  • Saudi Pharm J.2019, 27(1):145-153
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  • Chem Biol Interact.2019, 298:1-7
  • Pak J Pharm Sci.2019, 32(6):2879-2885
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  • J Sep Sci.2019, 42(21):3352-3362
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • ...
  • 生物活性
    Description: 4,9-Dimethoxycanthin-6-one is a natural product from Ailanthus altissima.
    In vitro:
    Nat Prod Commun. 2010 Jan;5(1):17-22.
    Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line.[Pubmed: 20184012]

    METHODS AND RESULTS:
    Phytochemical investigation of the stems of Eurycoma longifolia Jack led to the isolation of two new canthin-6-one alkaloids, 4,9-Dimethoxycanthin-6-one (1) and 10-hydroxy-11-methoxycanthin-6-one (2), and a new tirucallane-type triterpenoid, 23,24,25-trihydroxytirucall-7-en-3,6-dione (3), along with 37 known compounds. Among these, an oxasqualenoid (4) was isolated as a natural product for the first time. The structures of the isolates were elucidated by spectroscopic and mass spectrometric means. All the isolates were evaluated for their cytotoxic activity against a HT-1080 human fibrosarcoma cell line.
    CONCLUSIONS:
    Among them, 9,10-dimethoxycanthin-6-one (14, IC50 = 5.0 microM), 10-hydroxy-9-methoxycanthin-6-one (15, IC50 = 7.2 microM), dihydroniloticin (18, IC50 = 8.2 microM), and 14-deacetyleurylene (34, IC50 = 3.2 microM) displayed stronger activity than the positive control 5-FU (IC50 = 9.2 microM).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.5676 mL 17.838 mL 35.6761 mL 71.3521 mL 89.1902 mL
    5 mM 0.7135 mL 3.5676 mL 7.1352 mL 14.2704 mL 17.838 mL
    10 mM 0.3568 mL 1.7838 mL 3.5676 mL 7.1352 mL 8.919 mL
    50 mM 0.0714 mL 0.3568 mL 0.7135 mL 1.427 mL 1.7838 mL
    100 mM 0.0357 mL 0.1784 mL 0.3568 mL 0.7135 mL 0.8919 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    4,9-二甲氧基铁屎米酮; 4,9-Dimethoxycanthin-6-one CFN92128 1270001-72-3 C16H12N2O3 = 280.3 5mg QQ客服:3257982914
    5-羟基-6-铁屎米酮; 5-Hydroxy-canthin-6-one CFN92930 64118-73-6 C14H8N2O2 = 236.23 5mg QQ客服:1413575084
    5-甲氧基铁屎米酮; 5-Methoxycanthin-6-one CFN92362 15071-56-4 C15H10N2O2 = 250.3 5mg QQ客服:1413575084
    苦木西碱Q; Picrasidine Q CFN92205 101219-61-8 C15H10N2O3 = 266.3 10mg QQ客服:3257982914
    5-羟基-4-甲氧基铁屎米酮; 5-Hydroxy-4-methoxycanthin-6-one CFN99846 18110-86-6 C15H10N2O3 = 266.3 5mg QQ客服:215959384
    4,5-二甲氧基铁屎米酮; 4,5-Dimethoxycanthin-6-one CFN99847 18110-87-7 C16H12N2O3 = 280.3 5mg QQ客服:1148253675

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