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  • 2'-甲氧基肉桂醛

    o-Methoxycinnamaldehyde

    2'-甲氧基肉桂醛
    产品编号 CFN93299
    CAS编号 1504-74-1
    分子式 = 分子量 C10H10O2 = 162.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenols
    植物来源 The barks of Cinnamomum cassia Presl.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
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    2'-甲氧基肉桂醛 CFN93299 1504-74-1 10mg QQ客服:1148253675
    2'-甲氧基肉桂醛 CFN93299 1504-74-1 20mg QQ客服:1148253675
    2'-甲氧基肉桂醛 CFN93299 1504-74-1 50mg QQ客服:1148253675
    2'-甲氧基肉桂醛 CFN93299 1504-74-1 100mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J-STAGE2015, 249-255
  • Korean Journal of Pharmacognosy.2015, 46(4):352-364
  • Oncotarget.2015, 6(31):30831-49
  • J. Soc. Cosmet. Sci. Korea2016, 163-171
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  • Int J Mol Med.2016, 37(2):501-8
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  • Appl Microbiol Biotechnol.2018, 102(12):5105-5120
  • J Cell Biochem.2018, 119(2):2231-2239
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  • Chem Biol Interact.2018, 290:44-51
  • Korean Journal of Pharmacognosy2018, 49(1):76-83
  • Plant Cell Physiol.2018, 59(1):128-141
  • Korean J. Crop Sci.2018, 63(2):131-139
  • J Agric Food Chem.2018, 66(1):351-358
  • Planta Med.2018, 84(15):1101-1109
  • Front Aging Neurosci.2019, 11:230
  • Biomed Pharmacother.2019, 116:108987
  • ACS Chem Biol.2019, 14(5):873-881
  • Neuropharmacology2019, 151437
  • Korean J of Crop Science2019, 452-458
  • Appl Biochem Biotechnol.2020, 190(2):732-744
  • ...
  • 生物活性
    Description: o-Methoxycinnamaldehyde from cinnamon has antibiotic activity, it is a competitive inhibitor against CYP1A2 while it was a mixed type inhibitor against CYP2E.
    Targets: P450 (e.g. CYP17)
    In vivo:
    Xenobiotica. 1986 Sep;16(9):845-52.
    Metabolism of the cinnamon constituent o-methoxycinnamaldehyde in the rat.[Pubmed: 3765663]

    METHODS AND RESULTS:
    The metabolism of o-methoxycinnamaldehyde (1.3 mmol/kg, intragastrically) was studied in rats. Identification of the urinary metabolites by g.l.c.-mass spectrometry and quantification by h.p.l.c. showed that the major metabolic pathway (approx. two-thirds of the dose) was oxidation to the corresponding cinnamic and phenylpropionic acids (C6-C3 acids) which were largely excreted as glycine conjugates. Intermediate amounts (approx. 10% of the dose) of the O-demethylated C6-C3 acids were excreted. Relatively large amounts of the beta-hydroxylated phenylpropionic acid derivative were found, however only traces of the further products of beta-oxidation (2-methoxylated derivatives of benzoic and hippuric acid) were excreted.
    CONCLUSIONS:
    No evidence was obtained for conjugation of o-methoxycinnamaldehyde with glutathione. Urinary excretion of metabolites was rapid (91% in 24 h and 98% in 48 h).
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.1652 mL 30.8261 mL 61.6523 mL 123.3046 mL 154.1307 mL
    5 mM 1.233 mL 6.1652 mL 12.3305 mL 24.6609 mL 30.8261 mL
    10 mM 0.6165 mL 3.0826 mL 6.1652 mL 12.3305 mL 15.4131 mL
    50 mM 0.1233 mL 0.6165 mL 1.233 mL 2.4661 mL 3.0826 mL
    100 mM 0.0617 mL 0.3083 mL 0.6165 mL 1.233 mL 1.5413 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    肉桂醛; Cinnamaldehyde CFN99478 104-55-2 C9H8O = 132.2 20mg QQ客服:2159513211
    3-(2-羟基苯基)-2-丙烯醛; 3-(2-Hydroxyphenyl)-2-propenal CFN97017 60125-23-7 C9H8O2 = 148.2 5mg QQ客服:1413575084
    2'-甲氧基肉桂醛; o-Methoxycinnamaldehyde CFN93299 1504-74-1 C10H10O2 = 162.2 20mg QQ客服:1148253675
    4-甲氧基肉桂醛; 4-Methoxycinnamaldehyde CFN90559 1963-36-6 C10H10O2 = 162.19 20mg QQ客服:1413575084
    松柏醛; Coniferaldehyde CFN98037 20649-42-7 C10H10O3 = 178.2 5mg QQ客服:2932563308
    芥子醛; Sinapaldehyde CFN98038 20649-43-8 C11H12O4 = 208.2 5mg QQ客服:2159513211
    3-甲氧基-4,5-亚甲基二氧基肉桂醛; 3-Methoxy-4,5-methylenedioxycinnamaldehyde CFN97228 74683-19-5 C11H10O4 = 206.2 5mg QQ客服:2932563308

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