• 中药标准品生产商,产品定制服务
  • Science | Nature | Cell | View More

    络石苷

    Tracheloside

    络石苷
    产品编号 CFN90597
    CAS编号 33464-71-0
    分子式 = 分子量 C27H34O12 = 550.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The herbs of Trachelospermum jasminoides (Lindl.) Lem.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    络石苷 CFN90597 33464-71-0 10mg QQ客服:215959384
    络石苷 CFN90597 33464-71-0 20mg QQ客服:215959384
    络石苷 CFN90597 33464-71-0 50mg QQ客服:215959384
    络石苷 CFN90597 33464-71-0 100mg QQ客服:215959384
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Helsinki (Finland)
  • S.N.D.T. Women's University (India)
  • Vin?a Institute of Nuclear Sciences (Serbia)
  • Copenhagen University (Denmark)
  • Chang Gung University (Taiwan)
  • University of Limpopo (South Africa)
  • Universidade de Franca (Brazil)
  • Shanghai Institute of Organic Chemistry (China)
  • University of Illinois at Chicago (USA)
  • Universidad Industrial de Santander (Colombia)
  • University of Toronto (Canada)
  • University of Otago (New Zealand)
  • Kyushu University (Japan)
  • Universite de Lille1 (France)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Science and Biotechnology2015, 2205-2212
  • J Pharm Biomed Anal2016, 118:183-194
  • Sci Rep. 2017, 12953(7)
  • University of Central Lancashire2017, 20472
  • JPC-Journal of Planar Chromatography 2017, 30(4)
  • Sci Rep. 2018, 10590
  • J Chromatogr B Analyt Technol Biomed Life Sci.2018, 1080:27-36
  • Asian J of Pharmaceutical&Clinical 2018, 11(2)
  • Biosci Rep.2018, 38(4)
  • Plant Cell Physiol.2018, 59(1):128-141
  • J Nat Sc Biol Med2019, 10(2):149-156
  • Drug Invention Today2019, 12(6):1303-1306
  • J Pharm Biomed Anal.2019, 164:119-127
  • BMC Complement Altern Med.2019, 19(1):325
  • Int J Mol Sci.2019, 20(16):E4015
  • The Malaysian journal of pathology2019, 41(3):243-251
  • Journal of Functional Foods2019, 52:430-441
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Biomed Chromatogr.2019, 8:e4774
  • Sci Rep.2019, 9(1):18080
  • Sci Rep.2019, 9(1):4646
  • Food and Chemical Toxicology2020, 111221
  • J Ethnopharmacol.2020, 249:112396
  • ...
  • 生物活性
    Description: Tracheloside significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).
    Targets: Estrogen receptor | Progestogen receptor
    In vitro:
    Biosci Biotechnol Biochem. 2006 Nov;70(11):2783-5.
    An anti-estrogenic lignan glycoside, tracheloside, from seeds of Carthamus tinctorius.[Pubmed: 17090940]
    The lignan glycoside, tracheloside, was isolated from seeds of Carthamus tinctorius (Compositae) as an anti-estrogenic principle against cultured Ishikawa cells by employing a bioassay-linked HPLC-ELSD method.
    METHODS AND RESULTS:
    Tracheloside significantly decreased the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml).
    In vivo:
    Cancer Lett. 2003 Oct 28;200(2):133-9.
    Lack of significant inhibitory effects of a plant lignan tracheloside on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats.[Pubmed: 14568166]
    Tracheloside, one of the plant lignans which can be extracted from the debris after safflower oil is produced from the seeds of Carthamus tinctorious, is an analogue of another plant lignan, arctiin, the side-chain C-2 of the five-membered ring being changed from a hydrogen to a hydroxyl group. We have already demonstrated that arctiin has chemopreventive effect on mammary carcinogenesis. Therefore, chemopreventive effects of tracheloside on the initiation or post-initiation period of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female rats were examined.
    METHODS AND RESULTS:
    For initiation, female Sprague-Dawley (SD) rats at the 6 weeks of age were given intragastric administrations of 100 mg/kg body weight of PhIP once a week for 8 weeks. The animals were treated with 0.2 or 0.02% tracheloside during or after this carcinogen exposure. Control rats were fed basal diet with PhIP initiation or 0.2% tracheloside or basal diet alone without initiation throughout the experimental period. All surviving animals were necropsied at the week 52 of administration. There were no clear treatment-related changes with statistical significance in all parameters for mammary carcinomas measured in this experiment.
    CONCLUSIONS:
    These results indicate that tracheloside may not exert significant effects on PhIP-induced mammary carcinogenesis at least under the present experiment condition.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.8175 mL 9.0876 mL 18.1752 mL 36.3504 mL 45.438 mL
    5 mM 0.3635 mL 1.8175 mL 3.635 mL 7.2701 mL 9.0876 mL
    10 mM 0.1818 mL 0.9088 mL 1.8175 mL 3.635 mL 4.5438 mL
    50 mM 0.0364 mL 0.1818 mL 0.3635 mL 0.727 mL 0.9088 mL
    100 mM 0.0182 mL 0.0909 mL 0.1818 mL 0.3635 mL 0.4544 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    去甲络石苷; Nortracheloside CFN93080 33464-78-7 C26H32O12 = 536.53 5mg QQ客服:215959384
    络石苷; Tracheloside CFN90597 33464-71-0 C27H34O12 = 550.2 20mg QQ客服:3257982914
    络石苷元-4'-O-beta-龙胆二糖苷; Trachelogenin 4'-O-beta-gentiobioside CFN95235 106647-13-6 C33H44O17 = 712.7 10mg QQ客服:1148253675
    去甲络石苷元8'-O-β-葡萄糖苷; Nortrachelogenin-8'-O-beta-glucoside CFN95234 858127-38-5 C26H32O12 = 536.5 5mg QQ客服:1148253675
    Traxillaside; Traxillaside CFN96608 149415-62-3 C28H36O12 = 564.59 5mg QQ客服:1413575084
    Trachelosiaside; Trachelosiaside CFN89466 106647-12-5 C26H32O11 = 520.52 5mg QQ客服:2159513211
    Styraxlignolide F; Styraxlignolide F CFN92491 823214-06-8 C27H34O11 = 534.6 5mg QQ客服:215959384
    甲基牛蒡酚, 甲基牛蒡子素; 2,3-Bis(3,4-dimethoxybenzyl)butyrolactone CFN98281 25488-59-9 C22H26O6 = 386.4 5mg QQ客服:1413575084
    Tupichilignan A; Tupichilignan A CFN97182 69586-96-5 C22H26O7 = 402.4 5mg QQ客服:1413575084
    5-乙酰氧基罗汉松脂酚二甲醚; 5-Acetoxymatairesinol dimethyl ether CFN97230 74892-45-8 C24H28O8 = 444.5 5mg QQ客服:1148253675

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 215959384
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产