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  • 荛花酚

    (+)-Nortrachelogenin

    荛花酚
    产品编号 CFN96714
    CAS编号 61521-74-2
    分子式 = 分子量 C20H22O7 = 374.38
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The roots of Wikstroemia indica.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    荛花酚 CFN96714 61521-74-2 1mg QQ客服:2056216494
    荛花酚 CFN96714 61521-74-2 5mg QQ客服:2056216494
    荛花酚 CFN96714 61521-74-2 10mg QQ客服:2056216494
    荛花酚 CFN96714 61521-74-2 20mg QQ客服:2056216494
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Plants (Basel).2020, 9(11):1422.
  • Front. Plant Sci.2022, 13:757852.
  • Tea Res. Ins. Of China2017, 1-12
  • Int J Mol Sci.2020, 21(9):3239.
  • J Biomol Struct Dyn.2022, 1-21.
  • Environ Toxicol.2020, doi: 10.1002
  • Nutrients.2023, 15(6):1335.
  • Plant Physiol Biochem.2019, 144:355-364
  • Nutrients.2021, 13(12):4364.
  • Nutr Res Pract.2023, 17(4):670-681.
  • Food Res Int.2019, 123:125-134
  • Molecules.2023, 28(7):3039.
  • Jour. of Stored Pro & Postharvest Res.2016, 7(3):32-36
  • Foods.2022, 12(1):136.
  • Appl. Sci.2020, 10(20), 7323.
  • Sci Rep.2019, 9(1):18080
  • J Funct Foods2019, 54:449-456
  • Nat Prod Commun.2017, 12(5):771-778
  • Korean Journal of Medicinal Crop Science2018, 26(5):382-390
  • Plant Archives2020, 2(1),2929-2934
  • Sci Rep.2019, 9(1):4342
  • Chem Biol Interact.2019, 315:108910
  • Planta Med.2016, 82(13):1208-16
  • ...
  • 生物活性
    Description: (+)-Nortrachelogenin is moderately active against HIV-1 in vitro; it also can induce morphological deformation of P. oryzae mycelia with the MMDC value of 31.3 +/- 1.8 microM. (+)-Nortrachelogenin shows effects on the central nervous system producing depression in rabbits.
    Targets: HIV | Antifection
    In vitro:
    Lloydia. 1979 Mar-Apr;42(2):159-62.
    (+)Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica.[Pubmed: 449625]

    METHODS AND RESULTS:
    A new lignan, (+)-Nortrachelogenin (I), and a known compound, daphnoretin were isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae).
    CONCLUSIONS:
    The structure of (+)-Nortrachelogenin was established as 8(R)8'-4,4',8'-trihydroxy-3,3'-dimethoxylignan-olid, (9,9') on the basis of spectroscopic evidence and comparison with its enantiomer, (-)-nortrachelogenin. +-nortrachelogenin(I) showed effects on the central nervous system producing depression in rabbits.
    Planta Med. 2000 Aug;66(6):564-7.
    Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica.[Pubmed: 10985087]

    METHODS AND RESULTS:
    With guidance of Pyricularia oryzae bioassay, daphnoretin (1), (+)-Nortrachelogenin (2), genkwanol A (3), wikstrol A (4), wikstrol B (5) and daphnodorin B (6) were isolated from the roots of Wikstroemia indica. Compounds 1-6 induced morphological deformation of P. oryzae mycelia with MMDC values of 68.4 +/- 1.3, 31.3 +/- 1.8, 45.8 +/- 0.5, 70.1 +/- 2.4, 52.3 +/- 0.9 and 73.7 +/- 1.6 microM, respectively. Compounds 3-6 showed moderate activity against microtubule polymerization with IC50 values of 112 +/- 4, 131 +/- 3, 184 +/- 6 and 142 +/- 2 microM in vitro, respectively.
    CONCLUSIONS:
    Compounds 2, 3, 5 and 6 were moderately active against HIV-1 in vitro. The findings of bioactivity of 1-6 support the antifungus, antimitosis and anti-HIV-1 uses for W. indica roots.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6711 mL 13.3554 mL 26.7108 mL 53.4217 mL 66.7771 mL
    5 mM 0.5342 mL 2.6711 mL 5.3422 mL 10.6843 mL 13.3554 mL
    10 mM 0.2671 mL 1.3355 mL 2.6711 mL 5.3422 mL 6.6777 mL
    50 mM 0.0534 mL 0.2671 mL 0.5342 mL 1.0684 mL 1.3355 mL
    100 mM 0.0267 mL 0.1336 mL 0.2671 mL 0.5342 mL 0.6678 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    牛蒡酚B; Lappaol B CFN95242 62359-60-8 C31H34O9 = 550.6 10mg QQ客服:2159513211
    牛蒡酚C; Lappaol C CFN95068 64855-00-1 C30H34O10 = 554.6 10mg QQ客服:1413575084
    异牛蒡酚C; Isolappaol C CFN95225 929905-15-7 C30H34O10 = 554.6 10mg QQ客服:215959384
    牛蒡酚F; Lappaol F CFN95069 69394-17-8 C40H42O12 = 714.8 10mg QQ客服:2159513211
    (+)-罗汉松树脂酚 ; (+)-Matairesinol CFN96715 148409-36-3 C20H22O6 = 358.39 5mg QQ客服:215959384
    Isosalicifolin; Isosalicifolin CFN96234 156974-99-1 C20H20O6 = 356.4 5mg QQ客服:3257982914
    去甲络石甙元; Nortrachelogenin CFN98454 34444-37-6 C20H22O7 = 374.4 10mg QQ客服:1457312923
    荛花酚 ; (+)-Nortrachelogenin CFN96714 61521-74-2 C20H22O7 = 374.38 5mg QQ客服:2056216494
    (7R)-甲氧基-8-表-罗汉松树脂酚 ; (7R)-Methoxy-8-epi-matairesinol CFN89300 198827-23-5 C21H24O7 = 388.41 5mg QQ客服:1457312923
    络石苷元; Trachelogenin CFN90598 34209-69-3 C21H24O7 = 388.15 10mg QQ客服:1413575084

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