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  • 钓樟内酯

    Linderalactone

    钓樟内酯
    产品编号 CFN99761
    CAS编号 728-61-0
    分子式 = 分子量 C15H16O3 = 244.29
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Sesquiterpenoids
    植物来源 The roots of Lindera aggregata
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    钓樟内酯 CFN99761 728-61-0 10mg QQ客服:1413575084
    钓樟内酯 CFN99761 728-61-0 20mg QQ客服:1413575084
    钓樟内酯 CFN99761 728-61-0 50mg QQ客服:1413575084
    钓樟内酯 CFN99761 728-61-0 100mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Research Unit Molecular Epigenetics (MEG) (Germany)
  • Chiang Mai University (Thailand)
  • The Vancouver Prostate Centre (VPC) (Canada)
  • Utah State University (USA)
  • Melbourne University (Australia)
  • Nanjing University of Chinese Medicine (China)
  • Cornell University (USA)
  • Monash University (Australia)
  • University of Leipzig (Germany)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Pennsylvania State University (USA)
  • University of Bonn (Germany)
  • Shanghai Institute of Biochemistry and Cell Biology (China)
  • Universidad de Buenos Aires (Argentina)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Auburn University2015, 1-58
  • Oncotarget.2015, 6(31):30831-49
  • Food Chem.2016, 191:81-90
  • JPC-Journal of Planar Chromatography 2017, 30(4)
  • Cytotechnology.2017, 69(5):765-773
  • Industrial Crops and Products2017, 95:286-295
  • J Chromatogr B Analyt Technol Biomed Life Sci.2018, 1080:27-36
  • Asian J of Pharmaceutical&Clinical 2018, 11(2)
  • Pharmacognosy Magazine2018, 14(56):418-424
  • Evid Based Complement Alternat Med.2018, 2018:1073509
  • J Ethnopharmacol.2018, 210:88-94
  • Biosci Rep.2018, 38(4)
  • J of the Korean Society of Cosmetics and Cosmetology2018, 399-406
  • Front Immunol.2018, 9:2091
  • Toxins (Basel).2019, 11(10):E575
  • Int J Mol Sci.2019, 20(21):E5488
  • Cell Chem Biol.2019, 26(1):27-34
  • J of Dentistry & Oral Health2019, 2641-1962
  • Academic J of Second Military Medical University2019, 40(1)
  • Biomedicine & Pharmacotherapy2020, 125:109950
  • Food Res Int.2020, 128:108778
  • Int J Pharmacol2020, 16:1-9
  • J Ethnopharmacol.2020, 249:112381
  • ...
  • 生物活性
    Description: Linderalactone shows hepatoprotective activity against H2O2-induced oxidative damages on HepG2 cells with the EC(50) value of 98.0 microM. It shows significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, the IC50 is 8.48 microg/mL.
    Targets: Immunology & Inflammation related
    In vitro:
    Nat Prod Res. 2005 Apr;19(3):283-6.
    Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma.[Pubmed: 15702642]

    METHODS AND RESULTS:
    Six furanogermacrane sesquiterpenes, pseudoneolinderane (1), linderalactone (2), zeylanidine (3), zeylanicine (4), deacetylzeylanidine (5), and neolitrane (6), isolated from the stems of Neolitsea parvigemma, were tested for anti-inflammatory activities.
    CONCLUSIONS:
    Among them, 1 and 2 showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB. The IC50 of 1 and 2 were found to be 3.21 and 8.48 microg/mL, respectively.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.0935 mL 20.4675 mL 40.935 mL 81.8699 mL 102.3374 mL
    5 mM 0.8187 mL 4.0935 mL 8.187 mL 16.374 mL 20.4675 mL
    10 mM 0.4093 mL 2.0467 mL 4.0935 mL 8.187 mL 10.2337 mL
    50 mM 0.0819 mL 0.4093 mL 0.8187 mL 1.6374 mL 2.0467 mL
    100 mM 0.0409 mL 0.2047 mL 0.4093 mL 0.8187 mL 1.0234 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    1,2-环氧-10(14)-呋喃吉玛烯-6-酮; 1,2-Epoxy-10(14)-furanogermacren-6-one CFN95214 383368-24-9 C15H18O3 = 246.3 10mg QQ客服:215959384
    (1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one; (1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one CFN95219 1393342-06-7 C16H20O3 = 260.3 5mg QQ客服:2932563308
    乌药醚内酯; Linderane CFN98175 13476-25-0 C15H16O4 = 260.28 20mg QQ客服:1413575084
    伪新乌药醚内酯; Pseudoneolinderane CFN91936 20082-45-5 C15H16O4 = 260.29 5mg QQ客服:1148253675
    二氢焦蓬莪术酮; Dihydropyrocurzerenone CFN91911 59462-26-9 C15H18O = 214.30 5mg QQ客服:3257982914
    焦蓬莪术酮; Pyrocurzerenone CFN96169 20013-75-6 C15H16O = 212.3 20mg QQ客服:215959384
    Dehydrochromolaenin; Dehydrochromolaenin CFN96174 20013-76-7 C15H14O = 210.3 5mg QQ客服:215959384
    2-Methoxyfuranoguaia-9-ene-8-one; 2-Methoxyfuranoguaia-9-ene-8-one CFN95220 88010-62-2 C16H20O3 = 260.3 10mg QQ客服:1148253675
    2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one; 2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one CFN95197 1809980-25-3 C18H24O5 = 320.4 10mg QQ客服:2932563308
    异莪术呋喃二烯; Isofuranodiene CFN98971 57566-47-9 C15H20O = 216.3 5mg QQ客服:2932563308

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