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  • 灵芝酸C2

    Ganoderic acid C2

    灵芝酸C2
    产品编号 CFN92054
    CAS编号 103773-62-2
    分子式 = 分子量 C30H46O7 = 518.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Triterpenoids
    植物来源 The fruit body of Ganoderma lucidum.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    灵芝酸C2 CFN92054 103773-62-2 1mg QQ客服:215959384
    灵芝酸C2 CFN92054 103773-62-2 5mg QQ客服:215959384
    灵芝酸C2 CFN92054 103773-62-2 10mg QQ客服:215959384
    灵芝酸C2 CFN92054 103773-62-2 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Mysore (India)
  • National Hellenic Research Foundation (Greece)
  • Universidade Federal de Pernambuco (UFPE) (Brazil)
  • Harvard University (USA)
  • Weizmann Institute of Science (Israel)
  • Universidad Veracuzana (Mexico)
  • University of Toronto (Canada)
  • University of Cincinnati (USA)
  • Sapienza University of Rome (Italy)
  • University of Illinois (USA)
  • Mahidol University (Thailand)
  • Kyushu University (Japan)
  • Almansora University (Egypt)
  • University of Canterbury (New Zealand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Exp Parasitol.2015, 153:160-4
  • Tumour Biol.2015, 36(12):9385-93
  • J. Soc. Cosmet. Sci. Korea2016, 163-171
  • Food Chem.2016, 191:81-90
  • Chin. Med.J.Res. Prac.2017, 31(4)
  • Hum Exp Toxicol.2017, 36(11):1169-1176
  • Integr Med Res.2017, 6(4):395-403
  • The Japan Society for Analytical Chemistry2017, 613-617
  • Int. J. of Food Properties2017, S108-S118
  • PLoS One.2018, 13(11):e0208055
  • Sci Rep. 2018, 1-9
  • Int J Mol Sci.2018, 19(9):E2528
  • Molecules.2018, 23(7):E1659
  • Biofactors.2018, 44(2):168-179
  • Food and Fermentation Industries2018, 44(371)
  • Chemistry of Natural Compounds2018, 54(3):572–576
  • Drug Invention Today2019, 12(6):1303-1306
  • Asian Pac J Cancer Prev.2019, 20(1):65-72
  • Chemistry of Natural Compounds2019, 55(1):127-130
  • Saudi Pharm J2020, 10.1016
  • Biosci. Rep.2020, 10.1024
  • Plos One.2020, 10.1371
  • Antioxidants (Basel).2020, 9(2):E99
  • ...
  • 生物活性
    Description: Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen.
    Targets: Histamine Receptor | Immunology & Inflammation related
    In vitro:
    J Pharm Biomed Anal. 2013 Mar 5;75:64-73.
    Structural characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry.[Pubmed: 23312386]

    METHODS AND RESULTS:
    The metabolites and pharmacokinetics of ganoderic acid C2 (GAC2), a bioactive triterpenoid in Ganoderma lucidum in rat plasma were investigated by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). Totally, ten minor phase I metabolites of GAC2 were characterized after oral administration of GAC2, on the basis of their mass fragmentation pathways or direct comparison with authentic compounds by high-performance liquid chromatography coupled with diode array detection and electrospray ion trap tandem mass spectrometry (HPLC-DAD-ESI-MS(n)), and liquid chromatography coupled with electrospray ionization hybrid ion trap and time-of-flight mass spectrometry (LC-ESI-IT-TOF/MS) methods. Moreover, a rapid and specific method for quantification of GAC2 in rat plasma after oral administration was developed by using a liquid-liquid extraction procedure and HPLC-ESI-MS/MS analysis.
    CONCLUSIONS:
    It is the first time to report the metabolites and pharmacokinetics of GAC2.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9279 mL 9.6395 mL 19.279 mL 38.5579 mL 48.1974 mL
    5 mM 0.3856 mL 1.9279 mL 3.8558 mL 7.7116 mL 9.6395 mL
    10 mM 0.1928 mL 0.9639 mL 1.9279 mL 3.8558 mL 4.8197 mL
    50 mM 0.0386 mL 0.1928 mL 0.3856 mL 0.7712 mL 0.9639 mL
    100 mM 0.0193 mL 0.0964 mL 0.1928 mL 0.3856 mL 0.482 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    赤芝酸G甲酯; Methyl lucidente G CFN95058 102607-20-5 C28H42O7 = 490.6 5mg QQ客服:1413575084
    灵芝酸C1; Ganoderic acid C1 CFN92053 95311-97-0 C30H42O7 = 514.7 5mg QQ客服:2159513211
    灵芝酸LM2; Ganoderic acid LM2 CFN90297 508182-41-0 C30H42O7 = 514.66 5mg QQ客服:1148253675
    灵芝酸D; Ganoderic acid D CFN90292 108340-60-9 C30H42O7 = 514.66 10mg QQ客服:215959384
    12-羟基灵芝酸D; 12-Hydroxyganoderic acid D CFN91921 942950-96-1 C30H42O8 = 530.65 10mg QQ客服:1413575084
    12β-灵芝酸M; Ganoderic acid M CFN90747 100761-17-9 C30H42O8 = 530.7 5mg QQ客服:1148253675
    灵芝酸Z; Ganoderic acid Z CFN90295 294674-09-2 C30H42O7 = 514.66 5mg QQ客服:3257982914
    灵芝酸AM1; Ganoderic acid AM1 CFN90296 149507-55-1 C30H42O7 = 514.66 5mg QQ客服:215959384
    Ethyl ganoderate J; Ethyl ganoderate J CFN92576 1189555-95-0 C32H46O7 = 542.7 5mg QQ客服:2159513211
    灵芝酸B; Ganoderic acid B CFN92052 81907-61-1 C30H44O7 = 516.7 10mg QQ客服:2932563308

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