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  • 海胆灵

    Echinulin

    海胆灵
    产品编号 CFN99862
    CAS编号 1859-87-6
    分子式 = 分子量 C29H39N3O2 = 461.7
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 From Aspergillus chevalieri.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    海胆灵 CFN99862 1859-87-6 1mg QQ客服:215959384
    海胆灵 CFN99862 1859-87-6 5mg QQ客服:215959384
    海胆灵 CFN99862 1859-87-6 10mg QQ客服:215959384
    海胆灵 CFN99862 1859-87-6 20mg QQ客服:215959384
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Universiti Kebangsaan Malaysia (Malaysia)
  • Seoul National University of Science and Technology (Korea)
  • Korea Institute of Oriental Medicine (Korea)
  • Yale University (USA)
  • Universite Libre de Bruxelles (Belgium)
  • University of Hull (United Kingdom)
  • Periyar University (India)
  • University of Malaya (Malaysia)
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  • Deutsches Krebsforschungszentrum (Germany)
  • Aarhus University (Denmark)
  • University of Bonn (Germany)
  • Utah State University (USA)
  • Monash University Sunway Campus (Malaysia)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Natural Product Communications2020, doi: 10.1177.
  • Plant Physiol Biochem.2019, 144:355-364
  • Korean J. of Horticultural Sci. & Tech. 2017, 793-804
  • Molecules.2023, 28(9):3685.
  • Univerzita Karlova2021, 20.500.11956.
  • Food Res Int.2022, 157:111397.
  • National University of Pharmacy2022, 1:73-76
  • Enzyme Microb Technol.2019, 122:64-73
  • Plos One.2019, 15(2):e0220084
  • Recent Pat Anticancer Drug Discov.2022, 17(4):416-426.
  • Phytomedicine.2019, 59:152785
  • Phytomedicine.2022, 110:154597.
  • Int J Mol Sci.2015, 16(1):1232-51
  • Journal of Ginseng Research2021, 25 November
  • J Adv Res.2019, 17:85-94
  • Plant Physiol Biochem.2023, 203:108073.
  • Anticancer Res.2018, 38(4):2127-2135
  • Asian J Beauty Cosmetol2019, 17(3):287-294
  • Nutrients.2019, 12(1)
  • J Sep Sci.2022, 45(18):3556-3566.
  • Molecules.2019, 24(4):E709
  • Molecules2021, 26(1),230
  • Molecules.2023, 28(19):6775.
  • ...
  • 生物活性
    Description: Echinulin has toxicity in rabbits.
    In vitro:
    Appl Environ Microbiol. 1988 Mar;54(3):830-1.
    Eurotium spp. and echinulin in feed refused by swine.[Pubmed: 3377495]

    METHODS AND RESULTS:
    Feed refused by swine contained a high-propagule density of Eurotium chevalieri Mangin (anamorph, Aspergillus chevalieri (Mangin) Thom and Church), Eurotium amstelodami Mangin (anamorph, Aspergillus amstelodami (Mangin Thom and Church), and Aspergillus candidus Link. Echinulin (8 micrograms/g of feed) was detected in the feed. Isolates of E. chevalieri and E. amstelodami but not A. candidus produced Echinulin on rice or cracked corn.
    CONCLUSIONS:
    Mice refused to drink water containing 90 micrograms of Echinulin per ml. This is the first report of the alkaloid Echinulin in feed refused by swine.
    In vivo:
    Toxicol Lett. 1989 Sep;48(3):235-41.
    Toxicity of echinulin from Aspergillus chevalieri in rabbits.[Pubmed: 2781591]

    METHODS AND RESULTS:
    Rabbits were injected intraperitoneally with purified Echinulin, a product of Aspergillus chevalieri. After 2 h, the rabbits were bled and enzyme analyses were carried out on the supernates of liver homogenates and citrated plasma. Elevated levels of total plasma lactate dehydrogenase, cardiac derived isozyme, glutamic-oxaloacetic and glutamic-pyruvic transaminase activities in animals receiving toxin were observed. These levels were statistically significant compared to the vehicle control. A significant increase in liver lactate dehydrogenase of toxin-treated rabbits was also observed.
    CONCLUSIONS:
    Light-microscopic examination of lung and liver showed a significant degree of damage. The increase in plasma enzyme levels is indicative of damage to these organs.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1659 mL 10.8295 mL 21.6591 mL 43.3182 mL 54.1477 mL
    5 mM 0.4332 mL 2.1659 mL 4.3318 mL 8.6636 mL 10.8295 mL
    10 mM 0.2166 mL 1.083 mL 2.1659 mL 4.3318 mL 5.4148 mL
    50 mM 0.0433 mL 0.2166 mL 0.4332 mL 0.8664 mL 1.083 mL
    100 mM 0.0217 mL 0.1083 mL 0.2166 mL 0.4332 mL 0.5415 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    蓬莱葛胺; Gardneramine CFN98447 34274-91-4 C23H28N2O5 = 412.5 5mg QQ客服:215959384
    喹胺; Quinamine CFN96295 464-85-7 C19H24N2O2 = 312.4 5mg QQ客服:2056216494
    康奎明; Conquinamine CFN96329 464-86-8 C19H24N2O2 = 312.4 5mg QQ客服:1413575084
    二氢辛可胺; Dihydrocinchonamine CFN99043 10283-68-8 C19H26N2O = 298.4 5mg QQ客服:1413575084
    新海胆灵A; Neoechinulin A CFN98823 51551-29-2 C19H21N3O2 = 323.4 5mg QQ客服:3257982914
    海胆灵; Echinulin CFN99862 1859-87-6 C29H39N3O2 = 461.7 5mg QQ客服:2056216494
    Voafinidine; Voafinidine CFN96445 180059-77-2 C20H28N2O2 = 328.45 5mg QQ客服:2056216494
    Tryprostatin A; Tryprostatin A CFN96472 171864-80-5 C22H27N3O3 = 381.47 5mg QQ客服:2159513211

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