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  • 白藜芦醇三甲醚

    Trimethoxystilbene

    白藜芦醇三甲醚
    产品编号 CFN90874
    CAS编号 22255-22-7
    分子式 = 分子量 C17H18O3 = 270.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Polyphenols
    植物来源 The herbs of Sophora viciifolia.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    白藜芦醇三甲醚 CFN90874 22255-22-7 10mg QQ客服:1148253675
    白藜芦醇三甲醚 CFN90874 22255-22-7 20mg QQ客服:1148253675
    白藜芦醇三甲醚 CFN90874 22255-22-7 50mg QQ客服:1148253675
    白藜芦醇三甲醚 CFN90874 22255-22-7 100mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Anna University (India)
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  • University of Leipzig (Germany)
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  • Universidad Industrial de Santander (Colombia)
  • Mendel University in Brno (Czech Republic)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Nat Prod.2021, 84(9):2544-2553.
  • Oncotarget.2017, 9(3):4161-4172
  • Microorganisms.2021, 9(12):2514.
  • Separations2021, 8(1), 1.
  • Journal of Ginseng Research2021, 25 November
  • Sustainability2021, 13(23),12981.
  • Mol Biol Rep.2022, doi: 10.1007
  • Food Funct.2021, 12(4):1469-1481.
  • J Biochem Mol Toxicol.2021, 35(5):e22731.
  • J Pharmaceut Biomed2020, 182:113110
  • Korean Herb. Med. Inf. 2016, 4(1):35-42
  • J. Soc. Cosmet. Sci. Korea2021, 47(1):57-63
  • Molecules.2019, 24(12):E2286
  • Cell Chem Biol.2019, 26(1):27-34
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • Phytochem Anal.2022, doi: 10.1002
  • Int J Biol Macromol.2020, 169:342-351
  • Analytical Letters.2020, doi 10.1008
  • Anat Rec2018, 24264
  • Molecules.2019, 24(16):E2985
  • Biomed Pharmacother.2021, 137:111362.
  • Anticancer Res.2020, 40(10):5529-5538.
  • Planta Med.2018, 84(15):1101-1109
  • ...
  • 生物活性
    Description: Trimethoxystilbene has anti-cancer activity, it inhibits cancer cell growth by inducing multipolar cell mitosis.
    In vitro:
    Mol Carcinog. 2017 Mar;56(3):1117-26.
    The resveratrol analogue trimethoxystilbene inhibits cancer cell growth by inducing multipolar cell mitosis.[Pubmed: 27739192 ]
    Natural compounds are extensively studied for their potential use in traditional and non-traditional medicine. Several natural and synthetic Resveratrol analogues have shown interesting biological activities in the field of cancer chemoprevention.
    METHODS AND RESULTS:
    In the present study, we have focused on the ability of Resveratrol and two methoxylated derivatives (Trimethoxystilbene and Pterostilbene) to inhibit human cancer cell growth particularly analyzing their ability to interfere with tubulin dynamics at mitosis. We show that Trimethoxystilbene, differently from Resveratrol and Pterostilbene, alters microtubule polymerization dynamics in HeLa cells specifically inducing multipolar spindles and mitotic arrest coupled to a reduction of cell growth and an increase in apoptotic death by mitotic catastrophe.
    CONCLUSIONS:
    This work demonstrates that the structural modification of Rsv causes substantial changes in the mechanism of action of the derivatives. The presence of three extra methyl groups renders Trimethoxy very efficient in impairing cell proliferation by inducing mitotic catastrophe in cancer cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6996 mL 18.498 mL 36.9959 mL 73.9919 mL 92.4898 mL
    5 mM 0.7399 mL 3.6996 mL 7.3992 mL 14.7984 mL 18.498 mL
    10 mM 0.37 mL 1.8498 mL 3.6996 mL 7.3992 mL 9.249 mL
    50 mM 0.074 mL 0.37 mL 0.7399 mL 1.4798 mL 1.8498 mL
    100 mM 0.037 mL 0.185 mL 0.37 mL 0.7399 mL 0.9249 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Arundinin; Arundinin CFN91179 148225-38-1 C22H22O4 = 350.4 5mg QQ客服:2159513211
    白藜芦醇; Resveratrol CFN98791 501-36-0 C14H12O3 = 228.2 20mg QQ客服:2159513211
    乙酰白藜芦醇; Triacetylresveratrol CFN90895 42206-94-0 C20H18O6 = 354.4 20mg QQ客服:2159513211
    虎杖甙; Polydatin CFN99159 27208-80-6 C20H22O8 = 390.40 20mg QQ客服:2159513211
    白藜芦醇-3-O-β-D-(2''-O-没食子酰)-葡萄糖苷; Pieceid-2''-O-gallate CFN95226 105304-51-6 C27H26O12 = 542.5 10mg QQ客服:1148253675
    二氢藜芦醇; Dihydroresveratrol CFN98987 58436-28-5 C14H14O3 = 230.3 20mg QQ客服:2932563308
    二氢白藜芦醇3-O-葡萄糖甙; Dihydroresveratrol 3-O-glucoside CFN99021 100432-87-9 C20H24O8 = 392.4 5mg QQ客服:1148253675
    去氧土大黄苷元; Desoxyrhapontigenin CFN90854 33626-08-3 C15H14O3 = 242.3 10mg QQ客服:3257982914
    去氧土大黄苷; Desoxyrhaponticin CFN90911 30197-14-9 C21H24O8 = 404.4 20mg QQ客服:2932563308
    土大黄苷 6''-O-没食子酸酯; Rhaponticin 6''-O-gallate CFN91099 94356-23-7 C28H28O13 = 572.51 5mg QQ客服:215959384

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