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  • 赤式-愈创木基 beta-松柏基醚

    erythro-Guaiacylglycerol beta-coniferyl ether

    赤式-愈创木基 beta-松柏基醚
    产品编号 CFN97457
    CAS编号 890317-92-7
    分子式 = 分子量 C20H24O7 = 376.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Phenylpropanoids
    植物来源 The herbs of Leucaena leucocephala
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    赤式-愈创木基 beta-松柏基醚 CFN97457 890317-92-7 1mg QQ客服:1457312923
    赤式-愈创木基 beta-松柏基醚 CFN97457 890317-92-7 5mg QQ客服:1457312923
    赤式-愈创木基 beta-松柏基醚 CFN97457 890317-92-7 10mg QQ客服:1457312923
    赤式-愈创木基 beta-松柏基醚 CFN97457 890317-92-7 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • University of Limpopo (South Africa)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Int J Biol Macromol.2020, 169:342-351
  • Oncol Rep.2019, 41(4):2453-2463
  • The Korea Society of Pha.2014, 300-314
  • Korean Journal of Plant Resources2021, 34(1):52-58.
  • Fitoterapia.2022, 157:105130.
  • Chin J Pharm Anal.2019, 39(7):1217-1228
  • Food and Fermentation Industries2018, 44(371)
  • Cancers (Basel).2021, 13(17):4327.
  • Nutr Metab (Lond).2019, 16:31
  • J Inflamm Res.2022, 15:5347-5359.
  • J Nat Med.2022, 76(1):59-67.
  • Industrial Crops and Products2017, 95:286-295
  • Phytochem Anal.2021, 32(6):970-981.
  • Int J Mol Sci.2019, 20(8):E1855
  • GENENCELL2023, 25:4356740
  • Sci Rep.2023, 13(1):21690.
  • Biotechnol Bioeng.2020, 117(7):2198-2208.
  • Applied Biological Chemistry2020, 63:37.
  • Food Funct.2021, 12(4):1469-1481.
  • Applied Biological Chemistry2023, 66:42.
  • Evid Based Complement Alternat Med.2021, 2021:5023536.
  • Korean J. of Food Sci. and Tech2016, 172-177
  • Molecules.2019, 24(12):E2286
  • ...
  • 生物活性
    Description: erythro-Guaiacylglycerol beta-coniferyl ether displays significant inhibitory effects on NO production.
    Targets: NO
    In vitro:
    J Ethnopharmacol. 2014 May 14;153(3):737-43.
    Lignans from the stems of Clematis armandii ("Chuan-Mu-Tong") and their anti-neuroinflammatory activities.[Pubmed: 24661966 ]

    METHODS AND RESULTS:
    One new and sixteen known lignans were isolated and characterized. The absolute configuration of the new lignan, (7R,8S)-9-acetyl-dehydrodiconiferyl alcohol (1), was elucidated by a combination of 1D/2D NMR techniques and the Electronic Circular Dichroism (ECD) spectroscopy based on the empirical helicity rules.
    CONCLUSIONS:
    The anti-neuroinflammatory bioassay showed that compounds 1, (7R,8S)-dehydrodiconiferyl alcohol (2), erythro-guaiacylglycerol-β-coniferyl ether (5), and erythro-Guaiacylglycerol beta-coniferyl ether (6) displayed significant inhibitory effects on NO production. Among them, neolignans 1 and 2 exhibited more potent activities than the positive control (N(G)-monomethyl-L-arginine, L-NMMA), with an IC₅₀ value of 9.3 and 3.9 μM, respectively. Moreover, both 1 and 2 were also found to concentration-dependently suppress the TNF-α release in LPS-stimulated BV-2 cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6567 mL 13.2837 mL 26.5675 mL 53.135 mL 66.4187 mL
    5 mM 0.5313 mL 2.6567 mL 5.3135 mL 10.627 mL 13.2837 mL
    10 mM 0.2657 mL 1.3284 mL 2.6567 mL 5.3135 mL 6.6419 mL
    50 mM 0.0531 mL 0.2657 mL 0.5313 mL 1.0627 mL 1.3284 mL
    100 mM 0.0266 mL 0.1328 mL 0.2657 mL 0.5313 mL 0.6642 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    4-((2S,3S)-2,3-二氢-3-甲基-7-(1E)-1-丙烯基-1,4-苯并二氧杂环己-2-基)-1,3-苯二酚; 2',4'-Dihydroxy-3,7':4,8'-diepoxylign-7-ene CFN96353 666250-52-8 C18H18O4 = 298.3 5mg QQ客服:1413575084
    4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan; 4',9,9'-Trihydroxy-3'-methoxy-3,7'-epoxy-4,8'-oxyneolignan CFN99494 144881-21-0 C19H22O6 = 346.4 5mg QQ客服:215959384
    光叶花椒宁; Nitidanin CFN99809 171674-89-8 C21H24O8 = 404.4 5mg QQ客服:2056216494
    Dadahol A; Dadahol A CFN98636 405281-76-7 C39H38O12 = 698.7 5mg QQ客服:3257982914
    Demethylcarolignan E ; Demethylcarolignan E CFN96712 873694-46-3 C39H40O13 = 716.73 5mg QQ客服:1413575084
    咖啡酸酐; Caffeic anhydride CFN92330 854237-32-4 C18H14O7 = 342.3 5mg QQ客服:215959384
    肉豆蔻木脂素; Myrislignan CFN99752 171485-39-5 C21H26O6 = 374.43 20mg QQ客服:2159513211
    赤式-2-(4-烯丙基-2,6-二甲氧基苯氧基)-1-(4-羟基-3-甲氧基苯基)-丙烷-1-醇; 1-(3,4-dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol CFN92657 41535-95-9 C21H26O6 = 374.4 5mg QQ客服:215959384
    Acetylvirolin; Acetylvirolin CFN96736 916264-22-7 C23H28O6 = 400.47 5mg QQ客服:1457312923
    1-(4-羟基-3-甲氧基苯基)-2-[2-甲氧基-4-(3-羟基丙基)苯氧基]-3-丙醇; 4,9,9'-Trihydroxy-3,3'-dimethoxy-8,4'-oxyneolignan CFN97728 53505-68-3 C20H26O6 = 362.42 5mg QQ客服:2159513211

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