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  • (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚

    (Z)-3-Hydroxy-5-methoxystilbene

    (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚
    产品编号 CFN96398
    CAS编号 143207-76-5
    分子式 = 分子量 C15H14O2 = 226.3
    产品纯度 >=98%
    物理属性 Oil
    化合物类型 Phenols
    植物来源 The aerial parts of Polygonum glabrum.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚 CFN96398 143207-76-5 1mg QQ客服:1413575084
    (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚 CFN96398 143207-76-5 5mg QQ客服:1413575084
    (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚 CFN96398 143207-76-5 10mg QQ客服:1413575084
    (Z)-3-甲氧基-5-(2-苯乙烯基)苯酚 CFN96398 143207-76-5 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Parma (Italy)
  • Ain Shams University (Egypt)
  • Copenhagen University (Denmark)
  • Max Rubner-Institut (MRI) (Germany)
  • Medical University of South Carolina (USA)
  • Biotech R&D Institute (USA)
  • University of Perugia (Italy)
  • Ateneo de Manila University (Philippines)
  • Chungnam National University (Korea)
  • Shanghai Institute of Biochemistry and Cell Biology (China)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Gyeongsang National University (Korea)
  • University of Canterbury (New Zealand)
  • Chulalongkorn University (Thailand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Food Chem.2016, 191:81-90
  • J. of Med. Plant Research.2013, 90-151
  • Molecules.2016, 21(6)
  • Int J Mol Sci.2022, 23(10):5813.
  • Vietnam Journal of Food Control.2022, 5(2): 115-128.
  • Sci Rep.2017, 7:40345
  • Life Sci.2022, 311(Pt A):121157.
  • Toxins (Basel).2020, 12(4):210.
  • Int J Mol Sci. 2014, 15(5):8443-57
  • Mediators Inflamm. 2016, 2016:6189590
  • Life Sci.2018, 209:498-506
  • J Food Biochem.2019, 43(9):e12970
  • Toxicol Res.2019, 35(4):371-387
  • J Biochem Mol Toxicol.2020, 34(7):e22489.
  • Anesth Pain Med (Seoul).2020, 15(4):478-485.
  • Pharmaceutics.2021, 13(2):187.
  • Cell.2018, 172(1-2):249-261
  • Pak J Pharm Sci.2019, 32(6)
  • Appl Microbiol Biotechnol.2018, 102(12):5105-5120
  • Appl. Sci.2023, 13(17), 9653.
  • Korean J Dent Mater2020, 47(2):63-70.
  • J Sep Sci.2018, 41(7):1682-1690
  • Nat Prod Commun.2017, 12(5):771-778
  • ...
  • 生物活性
    Description: 3-Hydroxy-5-methoxystilbene exhibits in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 3.33 ug/mL in dormant phase and 3.33 ug/mL in active phase.
    Targets: Antifection
    In vitro:
    Nat Prod Res. 2015;29(22):2080-6
    A new butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum.[Pubmed: 25643642 ]

    METHODS AND RESULTS:
    Phytochemical investigation of the methanol extract of the aerial parts of Polygonum glabrum afforded one new natural product (-)-2-methoxy-2-butenolide-3-cinnamate (1) along with six known compounds, β-hydroxyfriedalanol (2), 3-hydroxy-5-methoxystilbene (3), (-) pinocembrin (4), sitosterol-(6'-O-palmitoyl)-3-O-β-D-glucopyranoside (5), (-) pinocembrin-5-methyl ether (6) and sitosterol-3-O-β-D-glucopyranoside (7).
    CONCLUSIONS:
    Compound 1 showed promising in vitro anti-HIV-1 activity against primary isolates HIV-1(UG070) (X4, subtype D) and HIV-1(VB59) (R5, subtype C) assayed using TZM-bl cell line with IC50 in the range of 15.68-22.43 μg/mL. The extract showed TI in the range of 19.19-27.37 with IC50 in the range of 10.90-15.55 μg/mL. Compounds 1, 3 and 4 exhibited in vitro anti-mycobacterium activity against Mycobacterium tuberculosis H37Ra with IC50 values of 1.43, 3.33 and 1.11 μg/mL in dormant phase and 2.27, 3.33 and 1.21 μg/mL in active phase, respectively. Compound 4 was found to be the most active antiproliferative with IC50 values of 1.88-11.00 μg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.4189 mL 22.0946 mL 44.1891 mL 88.3783 mL 110.4728 mL
    5 mM 0.8838 mL 4.4189 mL 8.8378 mL 17.6757 mL 22.0946 mL
    10 mM 0.4419 mL 2.2095 mL 4.4189 mL 8.8378 mL 11.0473 mL
    50 mM 0.0884 mL 0.4419 mL 0.8838 mL 1.7676 mL 2.2095 mL
    100 mM 0.0442 mL 0.2209 mL 0.4419 mL 0.8838 mL 1.1047 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    4-甲氧基-9,10-二氢菲-2,7-二醇; Coelonin CFN92693 82344-82-9 C15H14O3 = 242.3 5mg QQ客服:2056216494
    黄菲灵; Flavidinin CFN92692 83925-00-2 C16H14O3 = 254.3 5mg QQ客服:215959384
    Agrostophyllidin; Agrostophyllidin CFN92691 178439-50-4 C17H16O4 = 284.3 5mg QQ客服:3257982914
    Phoyunnanin C; Phoyunnanin C CFN92781 956344-38-0 C30H26O6 = 482.5 5mg QQ客服:1457312923
    4-甲氧基菲-2,7-二醇; Flavanthrin CFN92782 120090-80-4 C30H26O6 = 482.5 5mg QQ客服:2159513211
    Diosniposide B; Diosniposide B CFN95333 N/A C22H26O10 = 450.4 5mg QQ客服:2159513211
    去氢厄弗酚,去氢灯心草二酚; Dehydroeffusol CFN90814 137319-34-7 C17H14O2 = 250.3 10mg QQ客服:1413575084
    厄弗酚; Effusol CFN90815 73166-28-6 C17H16O2 = 252.3 10mg QQ客服:1457312923
    去氢灯心草酚; Dehydrojuncusol CFN95143 117824-04-1 C18H16O2 = 264.3 5mg QQ客服:1413575084
    6-甲基灯心草二酚; Juncusol CFN90813 62023-90-9 C18H18O2 = 266.3 5mg QQ客服:215959384

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