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  • 五脂素A1

    Wulignan A1

    五脂素A1
    产品编号 CFN99005
    CAS编号 117047-76-4
    分子式 = 分子量 C20H22O5 = 342.4
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Lignans
    植物来源 The stems of Schisandra henryi.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    五脂素A1 CFN99005 117047-76-4 1mg QQ客服:1457312923
    五脂素A1 CFN99005 117047-76-4 5mg QQ客服:1457312923
    五脂素A1 CFN99005 117047-76-4 10mg QQ客服:1457312923
    五脂素A1 CFN99005 117047-76-4 20mg QQ客服:1457312923
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Vienna (Austria)
  • National Hellenic Research Foundation (Greece)
  • Sant Gadge Baba Amravati University (India)
  • Universit?t Basel (Switzerland)
  • Instituto de Investigaciones Agropecuarias (Chile)
  • Universidad de Ciencias y Artes de Chiapas (Mexico)
  • Kamphaengphet Rajabhat University (Thailand)
  • University of Wisconsin-Madison (USA)
  • University of Beira Interior (Portugal)
  • VIT University (India)
  • Washington State University (USA)
  • Kyung Hee University (Korea)
  • University of Auckland (New Zealand)
  • Yale University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Sep Sci.2018, 41(9):1938-1946
  • Int J Mol Sci.2021, 22(9):5012.
  • Molecules.2019, 24(16):E3003
  • Antioxidants (Basel).2020, 9(2):E99
  • Molecules.2016, 21(6)
  • Processes2020, 8(12),1540.
  • Institut Pasteur Korea2020, doi: 10.21203.
  • Nutrients2020, 12(2):488
  • Korean j.of Pharm.2017, 70-76
  • Archives of Biological sciences2022, 00:21-21
  • Front Cell Dev Biol.2021, 9:638174.
  • Front Pharmacol.2021, 12:615157.
  • Molecules.2021, 26(6):1738.
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • Theranostics.2023, 13(9):3103-3116.
  • Acta Edulis Fungi2020, 27(02):63-76.
  • Front Aging Neurosci.2019, 11:230
  • Front Immunol.2018, 9:2091
  • Chem Pharm Bull (Tokyo).2019, 67(11):1242-1247
  • Mol Med Rep.2022, 25(1):8.
  • Molecules.2020, 25(23):5609.
  • Int J Mol Sci.2022, 23(24):16000.
  • LWT - Food Science and Technology2022, 164:113627
  • ...
  • 生物活性
    Description: Wulignan A1 exhibits activity against leukemia P-388 in vitro; it also may have anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities.
    Targets: Antifection
    In vitro:
    Acta Chimica Sinica,1988, 46(5):483-8.
    Studies on the Constituents of Schisandra Henryi Ⅴ. The Structures of Wulignan A1, A2, Epiwulignan A1 and Epischisandrone)[Reference: WebLink]

    METHODS AND RESULTS:
    Four new lignan compounds named Wulignan A1 (4), A_2(5), epiWulignan A1 (6) and epischisandrone(7), and three known lignan compounds, enshicine(1), epienshicine(2) and schisandrone(3), were isolated from the fruits of Schisandra henryi Clarke collected in the district of Yibin, Sichuan Province.
    CONCLUSIONS:
    In anticancer screening all the four new compounds exhibit the activity against leukemia P-388 in vitro. Wulignan A1(4),
    US 8414938 B2[P]. 2013.
    Schisandrae fructus extracts for inhibition or prevention of H1N1 influenza virus infection and its application thereof[Reference: WebLink]
    Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9206 mL 14.6028 mL 29.2056 mL 58.4112 mL 73.014 mL
    5 mM 0.5841 mL 2.9206 mL 5.8411 mL 11.6822 mL 14.6028 mL
    10 mM 0.2921 mL 1.4603 mL 2.9206 mL 5.8411 mL 7.3014 mL
    50 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.1682 mL 1.4603 mL
    100 mM 0.0292 mL 0.146 mL 0.2921 mL 0.5841 mL 0.7301 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    叶下珠新素; Phyltetralin CFN92069 123048-17-9 C24H32O6 = 416.5 5mg QQ客服:1457312923
    Isolintetralin; Isolintetralin CFN92070 145459-30-9 C23H28O6 = 400.5 5mg QQ客服:3257982914
    珠子草次素; Nirtetralin CFN92852 78185-63-4 C24H30O7 = 430.5 5mg QQ客服:215959384
    叶下珠次素; Hypophyllanthin CFN98431 33676-00-5 C24H30O7 = 430.5 5mg QQ客服:1457312923
    (-)-南烛木树脂酚; (-)-Lyoniresinol CFN92578 31768-94-2 C22H28O8 = 420.5 5mg QQ客服:215959384
    5-甲氧基异落叶松脂素 ; 5-Methoxyisolariciresinol CFN96710 136082-41-2 C21H26O7 = 390.43 5mg QQ客服:2159513211
    Spathulatol ; Spathulatol CFN96566 1373888-27-7 C30H34O9 = 538.59 5mg QQ客服:1413575084
    Cagayanin; Cagayanin CFN95480 99096-51-2 C42H50O10 = 714.9 20mg QQ客服:1457312923
    愈创木素; Guaiacin CFN97039 36531-08-5 C20H24O4 = 328.4 5mg QQ客服:215959384
    五脂素A1; Wulignan A1 CFN99005 117047-76-4 C20H22O5 = 342.4 5mg QQ客服:1413575084

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