Info: Read More
  • 中药标准品生产商,产品定制服务
  • 环氧长春碱,长春素

    Vinleurosine

    环氧长春碱,长春素
    产品编号 CFN90466
    CAS编号 23360-92-1
    分子式 = 分子量 C46H56N4O9 = 808.95
    产品纯度 >=98%
    物理属性 Cryst.
    化合物类型 Alkaloids
    植物来源 The herbs of Catharanthus roseus (L.) G. Don
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    环氧长春碱,长春素 CFN90466 23360-92-1 1mg QQ客服:1457312923
    环氧长春碱,长春素 CFN90466 23360-92-1 5mg QQ客服:1457312923
    环氧长春碱,长春素 CFN90466 23360-92-1 10mg QQ客服:1457312923
    环氧长春碱,长春素 CFN90466 23360-92-1 20mg QQ客服:1457312923
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题,请将产品存入冰霜并且样品瓶保持密封,产品可以存放长达24个月(2-8摄氏度)。

    2. 只要有可能,产品溶解后,您应该在同一天应用于您的实验。 但是,如果您需要提前做预实验,或者需要全部溶解,我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常,这些可用于长达两周。 使用前,打开样品瓶前,我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度,使用和处理的建议? 请发送电子邮件至:service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话:
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到:027-84254680

  • 提供订购信息
  • 为了方便客户的订购,请需要订购ChemFaces产品的客户,在下单的时候请提供下列信息,以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号(CAS No.或产品名称)
  • 2. 发货地址
  • 3. 联系方法 (联系人,电话)
  • 4. 开票抬头 (如果需要发票的客户)
  • 5. 发票地址(发货地址与发票地址不同)
  • 发货时间
    1. 付款方式为100%预付款客户,我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户,我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品,需要重新生产,我们有权告知客户,交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Toulouse (France)
  • University of British Columbia (Canada)
  • University of Hertfordshire (United Kingdom)
  • Florida International University (USA)
  • University of Sao Paulo (Brazil)
  • VIB Department of Plant Systems Biology, UGent (PSB) (Belgium)
  • University of Bonn (Germany)
  • Georgia Institute of Technology (USA)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Utrecht University (Netherlands)
  • MTT Agrifood Research Finland (Finland)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • Kyung Hee University (Korea)
  • Rio de Janeiro State University (Brazil)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Universidade Estadual Paulista2017, 42785
  • J Cell Biochem.2022, 123(7):1222-1236.
  • Cells.2021, 10(11):2919.
  • J Pain Res.2022, 15:3469-3478.
  • Front Pharmacol.2023, 14:1244655.
  • Phytomedicine.2021, 2(82):153452
  • Appl. Sci.2020, 10(16),5482.
  • Molecules.2021, 26(9):2802.
  • Saudi Pharm J.2019, 27(1):145-153
  • Anticancer Res.2022, 42(9):4403-4410.
  • Antibiotics.2022, 11(4), 510.
  • Food Research International2020, 108987
  • J Appl Microbiol.2022, 132(2):949-963.
  • Srinagarind Medical Journal2019, 34(1)
  • BMC Pharmacol Toxicol.2018, 19(1):5
  • Int Immunopharmacol.2023, 125:111175.
  • Reprod Toxicol.2020, 96:1-10.
  • Environ Toxicol.2019, 34(12):1354-1362
  • Korean J Dent Mater.2018, 45(2):139-146
  • Drug Test Anal.2018, 10(10):1579-1589
  • Front Pharmacol.2021, 12:765521.
  • Int J Mol Sci.2018, 19(9):E2601
  • Sains Malaysiana2022, 51(4):1143-1154
  • ...
  • 生物活性
    Description: Vinleurosine can partially inhibit the energy dependent transport of alpha-aminoisobutyric acid in Ehrlich ascites tumor cells.
    In vitro:
    J Cell Physiol. 1975 Oct;86(2 Pt 1):201-11.
    A reduction in energy-dependent amino acid transport by microtubular inhibitors in Ehrlich ascites tumor cells.[Pubmed: 1194361]
    Vincristine, other periwinkle alkaloids, and colchicine partially inhibit the energy dependent transport of alpha-aminoisobutyric acid in Ehrlich ascites tumor cells. The properties of this phenomenon were characterized in detail for vincristine. Maximum depression of the steady-state intracellular alpha-aminoisobutyric acid level was achieved with a vincristine concentration of less than 0.5 muM. The inhibitory effect of vincristine increases as the extracellular alpha-aminoisobutyric acid concentration is increased reaching a maximum, however, of only approximately to 25% at a level of 5 mM, leaving a large gradient for alpha-aminoisobutyric acid across the cell membrane. Vincristine produced an asymmetrical uptake rate, while increasing the efflux of alpha-aminoisobutyric acid. Inhibition of net alpha-aminoisobutyric acid transport by vincristine was partially reversible (approximately to 40%). Colchicine (50 muM) reduced the steady-state alpha-aminoisobutyric acid level by 30%, an effect that was not reversible. Inhibition by vinleurosine and vinrosidine was comparable to that of vincristine. Addition of glucose to the medium resulted in a small, but significant, decrease in the inhibitory effects of both vincristine and colchicine. The data indicate that these agents inhibit a small component of the uphill transport of alpha-aminoisobutyric acid in Ehrlich ascites tumor cells. The inhibitory effect of vincristine cannot be attributed to an increase in the passive permeability of the cell membrane to this agent. Rather, the data along with other studies from this laboratory suggest that vincristine reduces the energy-dependent transport of alpha-aminoisobutyric acid by either inhibiting cellular energy metabolism or by inhibiting cellular energy metabolism or by inhibiting the coupling of energy-metabolism to the transport of this amino acid and raises the possibility that cellular microtubules play a role in these processes.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2362 mL 6.1809 mL 12.3617 mL 24.7234 mL 30.9043 mL
    5 mM 0.2472 mL 1.2362 mL 2.4723 mL 4.9447 mL 6.1809 mL
    10 mM 0.1236 mL 0.6181 mL 1.2362 mL 2.4723 mL 3.0904 mL
    50 mM 0.0247 mL 0.1236 mL 0.2472 mL 0.4945 mL 0.6181 mL
    100 mM 0.0124 mL 0.0618 mL 0.1236 mL 0.2472 mL 0.309 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    酒石酸长春瑞滨; Vinorelbine Tartrate CFN90142 125317-39-7 C53H66N4O20 = 1079.11 20mg QQ客服:2159513211
    硫酸长春碱; Vinblastine Sulfate CFN90146 143-67-9 C46H58N4O9.H2SO4 = 909.06 20mg QQ客服:2056216494
    长春碱; Vinblastine CFN90230 865-21-4 C46H58N4O9 = 810.96 20mg QQ客服:3257982914
    脱水长春碱; 3',4'-Anhydrovinblastine CFN90246 38390-45-3 C46H56N4O8 = 792.96 5mg QQ客服:2056216494
    硫酸长春新碱; Vincristine sulfate CFN90400 2068-78-2 C46H58N4O14S = 923.04 20mg QQ客服:1413575084
    长春瑞滨; Vinorelbine CFN90401 71486-22-1 C45H54N4O8 = 778.93 20mg QQ客服:1413575084
    长春地辛; Vindesine CFN90465 53643-48-4 C43H55N5O7 = 753.92 5mg QQ客服:2056216494
    环氧长春碱,长春素; Vinleurosine CFN90466 23360-92-1 C46H56N4O9 = 808.95 5mg QQ客服:3257982914
    长春新碱; Vincristine CFN98589 57-22-7 C46H56N4O10 = 824.96 20mg QQ客服:1413575084

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用,不用于诊断或治疗程序。

    联系方式


    电机:027-84237783
    传真:027-84254680
    在线QQ: 1413575084
    E-Mail:manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家,科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产