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    维采宁-2

    Vicenin -2

    维采宁-2
    产品编号 CFN92031
    CAS编号 23666-13-9
    分子式 = 分子量 C27H30O15 = 594.5
    产品纯度 >=98%
    物理属性 Yellow powder
    化合物类型 Flavonoids
    植物来源 The herbs of Chrysanthemi indici L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    维采宁-2 CFN92031 23666-13-9 1mg QQ客服:1148253675
    维采宁-2 CFN92031 23666-13-9 5mg QQ客服:1148253675
    维采宁-2 CFN92031 23666-13-9 10mg QQ客服:1148253675
    维采宁-2 CFN92031 23666-13-9 20mg QQ客服:1148253675
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • Srinakharinwirot University (Thailand)
  • Institute of Chinese Materia Medica (China)
  • Biotech R&D Institute (USA)
  • Shanghai Institute of Organic Chemistry (China)
  • National Chung Hsing University (Taiwan)
  • Universidad Veracuzana (Mexico)
  • Monash University Malaysia (Malaysia)
  • Heidelberg University (Germany)
  • University of Otago (New Zealand)
  • Fraunhofer-Institut für Molekularbiologie und Angewandte ?kologie IME (Germany)
  • Guangzhou Institutes of Biomedicine and Health (China)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Mahidol University (Thailand)
  • University of Auckland (New Zealand)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Biol Chem.2014, 289(3):1723-31
  • Phytomedicine.2015, 22(4):498-503
  • Mol Cells.2015, 38(9):765-72
  • Asian J Beauty Cosmetol2016, 14(3):249-257
  • Acta Chromatographica2016, 29(3)
  • Nat Prod Commun.2017, 12(5):771-778
  • Int J Mol Sci.2017, 19(1)
  • Oncotarget.2017, 9(3):4161-4172
  • Analytical Methods2018, 10(27)
  • Asian Journal of Chemistry2018, 30(12):2699-2703
  • Phytomedicine.2018, 40:37-47
  • Food and Fermentation Industries2018, 44(371)
  • Chemistry of Natural Compounds2018, 54(3):572–576
  • Sci Rep.2018, 8(1):12970
  • Drug Invention Today2019, 12(6):1303-1306
  • Microb Pathog.2019, 131:128-134
  • Saudi Pharm J.2019, 27(1):145-153
  • Phytother Res.2019, 33(3):676-689
  • J Mol Histol.2019, 50(4):343-354
  • Aquaculture2019, 510:392-399
  • Appl Biol Chem2019, 62:46
  • Food Chem Toxicol.2020, 135:110863
  • Molecules.2020, 25(3):734
  • ...
  • 生物活性
    Description: Vicenin -2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin -2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin -2 could act as a UV light barrier to protect the plants.
    Targets: c-Myc | p53 | EGFR | Akt | mTOR
    In vitro:
    J Nat Prod. 2014 Mar 28;77(3):464-71.
    Evaluation of intestinal permeability of vicenin-2 and lychnopholic acid from Lychnophora salicifolia (Brazilian arnicão) using Caco-2 cells.[Pubmed: 24279746]
    Lychnophora salicifolia, commonly known as "arnicão", is used as an anti-inflammatory agent and as a flavoring agent in the Brazilian traditional spirit "cachaça".
    METHODS AND RESULTS:
    In this work, the permeation process of Vicenin -2 (1) and lychnopholic acid (2) (major secondary metabolites from the hydroalcoholic extract) was investigated using Caco-2 cells. For this investigation, a new HPLC-DAD method was developed and validated for the quantification step. It was observed that 2 crosses the Caco-2 cell monolayer by passive diffusion. On the other hand, 1 was not transported, suggesting no absorption and no efflux of this compound in Caco-2 cells.
    In vivo:
    Sci Rep. 2014 Mar 7;4:4309.
    Mass spectrometry of flavonoid vicenin-2, based sunlight barriers in Lychnophora species.[Pubmed: 24603617]
    Lychnophora salicifolia plants collected from four different places in Brazil (three states: Goias, Minas Gerais and Bahia) revealed a conserved accumulation of Vicenin -2 , a di-C-glycosyl flavonoid. Quantitative studies by UPLC-MS/MS showed high concentration of Vicenin -2 in leaves from sixty specimens of six Lychnophora species. So the tissue distributions of Vicenin -2 were evaluated in wild Lychnophora leaves (Asteraceae) by laser based imaging mass spectrometry (IMS) to propose its distributions and possible functions for the species analyzed. Mass spectrometric imaging revealed that Vicenin -2 , unlike other flavonoids, was produced at the top of the leaves. The combination of localization and UV absorption properties of Vicenin -2 suggests that it could act as a UV light barrier to protect the plants, since plants are sessile organisms that have to protect themselves from harsh external conditions such as intense sunlight.
    Phytomedicine. 2013 Mar 15;20(5):427-31.
    Testing of Perilla frutescens extract and Vicenin 2 for their antispasmodic effect.[Pubmed: 23357362]
    Gastrointestinal discomfort is frequently observed. The effects of Perilla frutescens extract and Vicenin -2 (a compound in this extract) were assayed in rat ileum with or without stimulation with acetylcholine or Ba(2+). Both had no direct spasmolytic effect, but both decreased acetylcholine- or Ba(2+)-induced contraction of rat ileum indicating an antispasmodic effect. This is valuable because effects were only observed when spasms were induced and may disturb the patient. The extract and the compound may be used to maintain and improve gut health.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6821 mL 8.4104 mL 16.8209 mL 33.6417 mL 42.0521 mL
    5 mM 0.3364 mL 1.6821 mL 3.3642 mL 6.7283 mL 8.4104 mL
    10 mM 0.1682 mL 0.841 mL 1.6821 mL 3.3642 mL 4.2052 mL
    50 mM 0.0336 mL 0.1682 mL 0.3364 mL 0.6728 mL 0.841 mL
    100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.3364 mL 0.4205 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    牡荆素-2''-O-鼠李糖苷; Vitexin-2''-O-rhamnoside CFN98177 64820-99-1 C27H30O14 = 578.52 20mg QQ客服:3257982914
    牡荆素-2''-O-葡萄糖苷; Vitexin 2''-glucoside CFN70421 61360-94-9 C27H30O15 = 594.5 5mg QQ客服:215959384
    牡荆素 2''-O-(4'''-O-乙酰)鼠李糖苷; Vitexin 2''-O-(4'''-O-acetyl)rhamnoside CFN96447 80537-98-0 C29H32O15 = 620.56 5mg QQ客服:3257982914
    牡荆素-4''-O-葡萄糖苷; Vitexin -4''-O-glucoside CFN92072 178468-00-3 C27H30O15 = 594.5 20mg QQ客服:3257982914
    芹菜素-6-C-α-L-阿拉伯糖-8-C-β-D-木糖苷; Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-xylopyranoside CFN90918 677021-30-6 C25H26O13 = 534.47 10mg QQ客服:2159513211
    维采宁-3; Vicenin -3 CFN92032 59914-91-9 C26H28O14 = 564.5 20mg QQ客服:2932563308
    夏佛塔苷; Schaftoside CFN90197 51938-32-0 C26H28O14 = 564.49 20mg QQ客服:3257982914
    新夏佛托苷; Neoschaftoside CFN92071 61328-41-4 C26H28O14 = 564.5 5mg QQ客服:215959384
    维采宁-1; Vicenin -1 CFN92030 35927-38-9 C26H28O14 = 564.5 5mg QQ客服:3257982914
    异夏佛塔苷; Isoschaftoside CFN92029 52012-29-0 C26H28O14 = 564.5 20mg QQ客服:215959384

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