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  • 氧化石蒜碱

    • 氧化石蒜碱

    Ungeremine

    氧化石蒜碱
    		产品编号 CFN93030
    CAS编号 72510-04-4
    分子式 = 分子量 C16H12NO3+ = 266.27
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Alkaloids
    植物来源 The bulbus of Lycoris radiata (L. Herit.) Herb
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    氧化石蒜碱 CFN93030 72510-04-4 10mg QQ客服：1413575084
    氧化石蒜碱 CFN93030 72510-04-4 20mg QQ客服：1413575084
    氧化石蒜碱 CFN93030 72510-04-4 50mg QQ客服：1413575084
    氧化石蒜碱 CFN93030 72510-04-4 100mg QQ客服：1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Instituto de Investigaciones Agropecuarias (Chile)
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  • Helmholtz Zentrum München (Germany)
  • Istanbul University (Turkey)
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  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Foods.2021, 10(11):2627.
  • Molecules.2015, 20(10):19172-88
  • J Ethnopharmacol.2019, 235:406-414
  • Enzyme Microb Technol.2022, 161:110111.
  • Cancers (Basel).2023, 15(1):293.
  • Rev. Chim.2020, 71(3),558-564
  • Korean J of Crop Science2019, 452-458
  • Molecules.2018, 23(9):E2121
  • Pharmacognosy Journal2019, 11(2): 369-373
  • Clin Exp Pharmacol Physiol.2020, doi: 10.1111
  • Earth Environ. Sci. 2021, 905:012080.
  • Synthetic and Systems Biotechnology2023, j.synbio.
  • Int J Mol Sci.2015, 16(8):18396-411
  • Molecules.2020, 25(23):5609.
  • Molecules.2019, 25(1):E103
  • University of Stuttgart2021, 11682.
  • Eur Rev Med Pharmacol Sci.2020, 24(9):5127-5139.
  • ACS Pharmacol. Transl. Sci.2023, 3c00129.
  • Nutrients2020, 12(3):811.
  • Pharmaceutics.2021, 13(2):187.
  • Phytomedicine.2022, 99:153997.
  • J Ethnopharmacol.2020, 269:113752.
  • Journal of Third Military Medical University2019, 41(2):110-115
  • ...
    • 生物活性
    Description: Ungeremine is a potential biofungicide against Penicillium roqueforti and Aspergillus niger, it has strong antibacterial activity against Flavobacterium columnare. Ungeremine also has antiprotozoal activity, it shows good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi. Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Ungeremine also shows strong acetylcholinesterase inhibitory activity(IC(50) value of 0.35 microM).
    Targets: Topoisomerase | Antifection | AChR
    In vitro:
    Nat Prod Res. 2018 Jul;32(13):1605-1610.
    Antimould microbial and plant metabolites with potential use in intelligent food packaging.[Pubmed: 29027475]
    Moulds food infestation is a heavy dangerous problem for human health and also could generate heavy economic losses.
    METHODS AND RESULTS:
    The intelligent packaging using eco-friendly biodegradable biofilm incorporating bioactive natural safe compounds represents a new frontier. This manuscript reports the inhibitory activity of 12 bacterial, fungal and plant metabolites against Penicillium roqueforti and Aspergillus niger. Among them α-costic acid and Ungeremine (3 and 12) are the most promising as potential biofungicide against both fungal strains. They inhibited fungal growth by more than 60% respect to the control at 72 h and this activity persisted also at 96 h.
    CONCLUSIONS:
    Ungeremine showed MIC90 lower than 0.003 mg/mL after 48 h of incubation and of 0.025 mg/mL at 72 h against P. roqueforti. The MIC90 value for A. niger was 0.2 mg/mL at 48 h for both compounds. The α-costic acid showed generally MIC values at 48 and 72 h higher than Ungeremine.
    Phytochemistry Letters, 2010, 3(3):161-163.
    In vitro antiprotozoal activity of alkaloids from Phaedranassa dubia (Amaryllidaceae)[Reference: WebLink]
    The bulbs of Phaedranassa dubia (Amaryllidaceae) were found to contain the novel compound phaedranamine, together with seven known alkaloids.
    METHODS AND RESULTS:
    The structure and stereochemistry of the alkaloids were determined by physical and spectroscopic methods. An in vitro screening against four different parasitic protozoa was carried out using the isolated compounds.
    CONCLUSIONS:
    The alkaloids Ungeremine, pseudolycorine and haemanthamine showed good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi and Plasmodium falciparum with IC50 values in the range of 3.66 μM or lower.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.7556 mL 18.7779 mL 37.5559 mL 75.1117 mL 93.8897 mL
    5 mM 0.7511 mL 3.7556 mL 7.5112 mL 15.0223 mL 18.7779 mL
    10 mM 0.3756 mL 1.8778 mL 3.7556 mL 7.5112 mL 9.389 mL
    50 mM 0.0751 mL 0.3756 mL 0.7511 mL 1.5022 mL 1.8778 mL
    100 mM 0.0376 mL 0.1878 mL 0.3756 mL 0.7511 mL 0.9389 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    氢溴酸加兰他敏; Galantamine hydrobromide CFN90744 1953-04-4 C17H22BrNO3 = 368.3 20mg QQ客服：215959384
    加兰他敏N-氧化物; Galanthamine 10-Oxide(Galanthamine N-Oxide) CFN91709 134332-50-6 C17H21NO4 = 303.4 5mg QQ客服：3257982914
    乙酰加兰他敏; O-Acetylgalanthamine CFN91707 25650-83-3 C19H23NO4 = 329.4 5mg QQ客服：3257982914
    那维定; Galanthaminone CFN90742 510-77-0 C17H19NO3 = 285.3 10mg QQ客服：2056216494
    二氢石蒜碱; Dihydrolycorine CFN90331 6271-21-2 C16H19NO4 = 289.33 20mg QQ客服：3257982914
    伪石蒜碱; Pseudolycorine CFN98548 29429-03-6 C16H19NO4 = 289.33 5mg QQ客服：2056216494
    盐酸石蒜碱; Lycorine chloride CFN99730 2188-68-3 C16H17NO4Cl = 323.78 20mg QQ客服：1457312923
    氧化石蒜碱; Ungeremine CFN93030 72510-04-4 C16H12NO3+ = 266.27 20mg QQ客服：3257982914
    二氢加兰他敏; Lycoramine CFN90745 21133-52-8 C17H23NO3 = 289.4 5mg QQ客服：2056216494
    O-去甲基加兰他敏; O-Desmethyl galanthamine CFN91708 60755-80-8 C16H19NO3 = 273.3 5mg QQ客服：215959384

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