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  • 土克甾酮

    Turkesterone

    土克甾酮
    产品编号 CFN90217
    CAS编号 41451-87-0
    分子式 = 分子量 C27H44O8 = 496.64
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The herbs of Cyanotis arachnoides C. B. Clarke.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    土克甾酮 CFN90217 41451-87-0 1mg QQ客服:1413575084
    土克甾酮 CFN90217 41451-87-0 5mg QQ客服:1413575084
    土克甾酮 CFN90217 41451-87-0 10mg QQ客服:1413575084
    土克甾酮 CFN90217 41451-87-0 20mg QQ客服:1413575084
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Vigo (Spain)
  • Seoul National University of Science and Technology (Korea)
  • Kyung Hee University (Korea)
  • Kitasato University (Japan)
  • China Medical University (Taiwan)
  • Kazusa DNA Research Institute (Japan)
  • University of Ioannina (Greece)
  • University of Bordeaux (France)
  • Universitas islam negeri Jakarta (Indonesia)
  • Aarhus University (Denmark)
  • Molecular Biology Institute of Barcelona (IBMB)-CSIC (Spain)
  • Stanford University (USA)
  • Institute of Chinese Materia Medica (China)
  • University of Parma (Italy)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Chromatogr B Analyt Technol Biomed Life Sci.2018, 1080:27-36
  • Inflammation2015, 38(1):445-55
  • Reprod Sci.2022,10.1007/s43032-022-01117-4.
  • J Med Food.2016, 19(12):1155-1165
  • Applied Biological Chemistry2022, 65(77).
  • BMB Rep.2020, 53(4):218-222.
  • Plants (Basel).2022, 11(21):2947.
  • Biosci. Rep.2020, 10.1024
  • Korean Journal of Pharmacognosy2018, 49(3):270-277
  • Chem Biol Interact.2020, 328:109200.
  • Oxid Med Cell Longev.2021, 2021:4883398.
  • PLoS One.2018, 13(4):e0195642
  • Int Immunopharmacol.2019, 71:361-371
  • J Sep Sci.2020, 43(22):4148-4161.
  • Int J Mol Sci.2022, 23(23):15213.
  • Viruses.2017, 9(10)
  • J Pharm Biomed Anal.2017, 140:274-280
  • Inflammation.2015, 38(4):1502-16
  • Evid Based Complement Alternat Med.2018, 2018:4259603
  • J Chromatogr B Analyt Technol Biomed Life Sci.2019, 1124:323-330
  • Pest Manag Sci.2019, 75(9):2530-2541
  • J Ethnopharmacol.2022, 289:115018.
  • Histol Histopathol.2022, 18518.
  • ...
  • 生物活性
    Description: Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions.
    Targets: Immunology & Inflammation related | Calcium Channel
    In vivo:
    Vopr Med Khim. 1986 Sep-Oct;32(5):24-8.
    Comparative study of the effect of ecdysterone, turkesterone and nerobol on the function of rat liver mitochondria in experimental diabetes[Pubmed: 3776112 ]

    METHODS AND RESULTS:
    Oxidative phosphorylation and Ca2+-transport functions of liver mitochondria were normalized in rats with alloxane diabetes after peroral administration of phytoecdisteroids - ecdisterone and Turkesterone (5 mg/kg) or nerobol (10 mg/kg) within 15 days.
    CONCLUSIONS:
    These drugs normalized the activity of NADH dehydrogenase and succinate dehydrogenase in respiratory chain of mitochondria, increased distinctly stability of the enzymes to the effect of such factors as heating, effect of phospholipase A2 or trypsin.
    Pharm.Chem. J., 2010, 44(1):7-9.
    Immunomodulating and antistress activity of ecdysterone and turkesterone under immobilization-induced stress conditions in mice.[Reference: WebLink]

    METHODS AND RESULTS:
    The phytoecdysteroids ecdysterone and turkesterone isolated from Rhaponticum integrifolium and Ajuga turkestanica herbs, respectively, increase the adaptation capacity of mice under immobilization-induced stress conditions. These compounds prevent involution of the thymicolymphatic system, decrease trophic disorders in gastric mucosa, prevent an increase in the weight of adrenal glands and a decrease in them of the content of ascorbic acid and cholesterol (to a much greater degree than does T-activin), and stimulate immunogenesis in animals with experimental immune deficiency developed on the background of immobilization-induced stress. Key wordsecdysterone-turkesterone-T-activin-immobilization-induced stress-immobilization.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0135 mL 10.0677 mL 20.1353 mL 40.2706 mL 50.3383 mL
    5 mM 0.4027 mL 2.0135 mL 4.0271 mL 8.0541 mL 10.0677 mL
    10 mM 0.2014 mL 1.0068 mL 2.0135 mL 4.0271 mL 5.0338 mL
    50 mM 0.0403 mL 0.2014 mL 0.4027 mL 0.8054 mL 1.0068 mL
    100 mM 0.0201 mL 0.1007 mL 0.2014 mL 0.4027 mL 0.5034 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    20-羟基蜕皮甾酮; 20-Hydroxyecdysone CFN98873 5289-74-7 C27H44O7 = 480.6 20mg QQ客服:2056216494
    水龙骨甾酮B; Polypodine B CFN89545 18069-14-2 C27H44O8 = 496.63 5mg QQ客服:215959384
    蜕皮甾酮-20,22-单丙酮化物; Ecdysterone 20,22-monoacetonide CFN98229 22798-96-5 C30H48O7 = 520.7 5mg QQ客服:215959384
    蜕皮甾酮2,3:20,22- 二缩丙酮; Ecdysterone 2,3:20,22-diacetonide CFN98230 22798-98-7 C33H52O7 = 560.8 5mg QQ客服:1413575084
    维生素D3; Vitamin D3 CFN90027 67-97-0 C27H44O = 384.64 20mg QQ客服:1413575084
    维生素D2; Ergocalciferol CFN90049 50-14-6 C28H44O = 396.65 20mg QQ客服:1413575084
    二氢胆固醇; Dihydrocholesterol CFN90608 80-97-7 C27H48O = 388.67 20mg QQ客服:2159513211
    胆固醇; 胆甾醇; Cholesterol CFN90040 57-88-5 C27H46O = 386.67 20mg QQ客服:2056216494
    4β-羟基胆固醇; 4-Beta-Hydroxycholesterol CFN90611 17320-10-4 C27H46O2 = 402.66 5mg QQ客服:1413575084
    7β-羟基胆固醇; 7Beta-Hydroxycholesterol CFN90610 566-27-8 C27H46O2 = 402.65 5mg QQ客服:2056216494

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