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    白藜芦醇三甲醚

    Trimethoxystilbene

    白藜芦醇三甲醚
    产品编号 CFN90874
    CAS编号 22255-22-7
    分子式 = 分子量 C17H18O3 = 270.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Polyphenols
    植物来源 The herbs of Sophora viciifolia.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    白藜芦醇三甲醚 CFN90874 22255-22-7 10mg QQ客服:2932563308
    白藜芦醇三甲醚 CFN90874 22255-22-7 20mg QQ客服:2932563308
    白藜芦醇三甲醚 CFN90874 22255-22-7 50mg QQ客服:2932563308
    白藜芦醇三甲醚 CFN90874 22255-22-7 100mg QQ客服:2932563308
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学,并且还在增涨
  • University of Wollongong (Australia)
  • Universiti Malaysia Pahang (Malaysia)
  • Texas A&M University (USA)
  • University of Maryland (USA)
  • Universidad Industrial de Santander (Colombia)
  • University of Padjajaran (Indonesia)
  • Sant Gadge Baba Amravati University (India)
  • Chulalongkorn University (Thailand)
  • Worcester Polytechnic Institute (USA)
  • Ain Shams University (Egypt)
  • University of Toronto (Canada)
  • Utrecht University (Netherlands)
  • University of Brasilia (Brazil)
  • Washington State University (USA)
  • More...
  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Asian Journal of Chemistry2014, 26(8):2425
  • HortTechnology2016, 26(6):816-819
  • Acta horticulturae2017, 1158:257-268
  • Int J Mol Sci.2017, 18(12)
  • Molecules.2017, 22(2)
  • Cytotechnology.2017, 69(5):765-773
  • Nutrients.2018, 11(1):E17
  • Neuropharmacology.2018, 131:68-82
  • Mol Pharm.2018, 15(8):3285-3296
  • Integr Cancer Ther.2018, 17(3):832-843
  • Evid Based Complement Alternat Med.2018, 2018:8565132
  • International Food Research Journal2018, 25(6):2560-2571
  • Pharmacol Rep.2018, 70(6):1195-1201
  • APMIS.2019, 127(10):688-695
  • J of Physics Conference Series2019, 1349(1)
  • Int J Mol Sci.2019, 20(8):E1855
  • Molecules.2019, 24(10):E1926
  • Chem Biol Interact.2019, 315:108910
  • Kor. J. Herbol.2019, 34(2):59-66
  • Nutr Res Pract.2020, 14(5):478-489.
  • Int J Mol Sci.2020, 21(7):2530.
  • Biochem Biophys Res Commun.2020, 530(1):4-9.
  • Phytomedicine.2021, 2(82):153452
  • ...
  • 生物活性
    Description: Trimethoxystilbene has anti-cancer activity, it inhibits cancer cell growth by inducing multipolar cell mitosis.
    In vitro:
    Mol Carcinog. 2017 Mar;56(3):1117-26.
    The resveratrol analogue trimethoxystilbene inhibits cancer cell growth by inducing multipolar cell mitosis.[Pubmed: 27739192 ]
    Natural compounds are extensively studied for their potential use in traditional and non-traditional medicine. Several natural and synthetic Resveratrol analogues have shown interesting biological activities in the field of cancer chemoprevention.
    METHODS AND RESULTS:
    In the present study, we have focused on the ability of Resveratrol and two methoxylated derivatives (Trimethoxystilbene and Pterostilbene) to inhibit human cancer cell growth particularly analyzing their ability to interfere with tubulin dynamics at mitosis. We show that Trimethoxystilbene, differently from Resveratrol and Pterostilbene, alters microtubule polymerization dynamics in HeLa cells specifically inducing multipolar spindles and mitotic arrest coupled to a reduction of cell growth and an increase in apoptotic death by mitotic catastrophe.
    CONCLUSIONS:
    This work demonstrates that the structural modification of Rsv causes substantial changes in the mechanism of action of the derivatives. The presence of three extra methyl groups renders Trimethoxy very efficient in impairing cell proliferation by inducing mitotic catastrophe in cancer cells.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6996 mL 18.498 mL 36.9959 mL 73.9919 mL 92.4898 mL
    5 mM 0.7399 mL 3.6996 mL 7.3992 mL 14.7984 mL 18.498 mL
    10 mM 0.37 mL 1.8498 mL 3.6996 mL 7.3992 mL 9.249 mL
    50 mM 0.074 mL 0.37 mL 0.7399 mL 1.4798 mL 1.8498 mL
    100 mM 0.037 mL 0.185 mL 0.37 mL 0.7399 mL 0.9249 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    Pinostilbenoside; Pinostilbenoside CFN98995 58762-96-2 C21H24O8 = 404.4 5mg QQ客服:1457312923
    3-羟基-5-甲氧基二苯乙烯; 5-Methoxy-3-stilbenol CFN92587 5150-38-9 C15H14O2 = 226.3 5mg QQ客服:3257982914
    Thunalbene; Thunalbene CFN92783 220862-05-5 C15H14O3 = 242.3 5mg QQ客服:2056216494
    3'-O-甲基山药素III; 3'-O-Methylbatatasin III CFN91176 101330-69-2 C16H18O3 = 258.3 5mg QQ客服:1413575084
    Batatasin III; Batatasin III CFN92689 56684-87-8 C15H16O3 = 244.3 5mg QQ客服:2932563308
    3-甲氧基-5-[2-(2-甲氧基苯基)乙基]苯酚; Stilbostemin N CFN97863 1000676-45-8 C16H18O3 = 258.32 5mg QQ客服:1413575084
    紫檀芪; Pterostilbene CFN90397 537-42-8 C16H16O3 = 256.30 20mg QQ客服:1413575084
    3-羟基-4',5-二甲氧基二苯乙烯; 3-Hydroxy-4',5-dimethoxystilbene CFN95199 58436-29-6 C16H16O3 = 256.3 10mg QQ客服:3257982914
    白藜芦醇三甲醚; Trimethoxystilbene CFN90874 22255-22-7 C17H18O3 = 270.3 20mg QQ客服:2159513211
    3,5-二甲氧基-3'-羟基联苄; 3,5-Dimethoxy-3'-hydroxybibenzyl CFN89540 168281-05-8 C16H18O3 = 258.31 5mg QQ客服:2056216494

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