Info: Read More
    		•
  • 中药标准品生产商，产品定制服务
    		•
  • 首页
  • 天然产物
  • 产品文献
  • 最新产品
  • 订购流程
  • 公司新闻
  • 公司简介
  • 联系我们
  • 首页
  • /
  • 天然产物（标准品）
  • /
  • 蒺藜皂苷D

    • 蒺藜皂苷D

    Terrestrosin D

    蒺藜皂苷D
    		产品编号 CFN90821
    CAS编号 179464-23-4
    分子式 = 分子量 C50H80O23 = 1049.2
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Steroids
    植物来源 The herbs of Tribulus terrestris L.
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    蒺藜皂苷D CFN90821 179464-23-4 1mg QQ客服：3257982914
    蒺藜皂苷D CFN90821 179464-23-4 5mg QQ客服：3257982914
    蒺藜皂苷D CFN90821 179464-23-4 10mg QQ客服：3257982914
    蒺藜皂苷D CFN90821 179464-23-4 20mg QQ客服：3257982914
    存储与注意事项
    1. 在您收到产品后请检查产品。如无问题，请将产品存入冰霜并且样品瓶保持密封，产品可以存放长达24个月（2-8摄氏度）。

    2. 只要有可能，产品溶解后，您应该在同一天应用于您的实验。 但是，如果您需要提前做预实验，或者需要全部溶解，我们建议您将溶液以等分试样的形式存放在-20℃的密封小瓶中。 通常，这些可用于长达两周。 使用前，打开样品瓶前，我们建议您将产品平衡至室温至少1小时。

    3. 需要更多关于溶解度，使用和处理的建议？ 请发送电子邮件至：service@chemfaces.com
    订购流程
  • 1. 在线订购
  • 请联系我们QQ客服

  • 2. 电话订购
  • 请拨打电话：
    027-84237683 或 027-84237783

  • 3. 邮件或传真订购
  • 发送电子邮件到: manager@chemfaces.com 或
    发送传真到：027-84254680

    • 提供订购信息
  • 为了方便客户的订购，请需要订购ChemFaces产品的客户，在下单的时候请提供下列信息，以供我们快速为您建立发货信息。
  •  
  • 1. 产品编号（CAS No.或产品名称）
  • 2. 发货地址
  • 3. 联系方法 (联系人，电话）
  • 4. 开票抬头 (如果需要发票的客户）
  • 5. 发票地址（发货地址与发票地址不同）
    • 发货时间
    1. 付款方式为100%预付款客户，我们将在确认收到货款后当天或1-3个工作日发货。

    2. 付款方式为月结的客户，我们承诺在收到订单后当天或1-3个工作日内发货。

    3. 如果客户所需要的产品，需要重新生产，我们有权告知客户，交货时间需要延期。
    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    我们的产品现已经出口到下面的研究机构与大学，并且还在增涨
  • Michigan State University (USA)
  • Sanford Burnham Prebys Medical Discovery Institute (USA)
  • Center for protein Engineering (CIP) (Belgium)
  • Harvard University (USA)
  • Heinrich-Heine-University Düsseldorf (Germany)
  • University of East Anglia (United Kingdom)
  • Subang Jaya Medical Centre (Malaysia)
  • National Cancer Institute (USA)
  • Universidad de La Salle (Mexico)
  • Sapienza University of Rome (Italy)
  • Kamphaengphet Rajabhat University (Thailand)
  • Weizmann Institute of Science (Israel)
  • Sri Sai Aditya Institute of Pharmaceutical Sciences and Research (India)
  • Aveiro University (Portugal)
  • More...
    • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • Oncol Rep.2019, 41(4):2453-2463
  • Acta Agriculturae Scandinavica2015, 381-383
  • Fitoterapia.2015, 100:179-86
  • J Sep Sci.2021, 44(22):4064-4081.
  • Internoational J of Toxicology2020, 10.1177.
  • J of Applied Pharmaceutical Science2020, 10(1):077-082
  • Evid Based Complement Alternat Med.2020, 2020:8582318.
  • Institut Pasteur Korea2020, doi: 10.21203.
  • Int. J. of Food Properties2017, S108-S118
  • Plant Foods Hum Nutr.2020, 10.1007
  • Molecules.2021, 26(9):2791.
  • Chin. Med.J.Res. Prac.2017, 31(4)
  • Pharmaceuticals (Basel).2020, 13(10):302.
  • Oxid Med Cell Longev.2021, 2021:6647107.
  • Agronomy2023, 13(6), 1435.
  • Sci Rep.2019, 9:12132
  • Natural Product Communications2022, 7(3):1-7.
  • Food Chemistry: X.2022, 2022.100270
  • Onco Targets Ther.2017, 10:3467-3474
  • Applied Physics B2021, 127(92).
  • Biomedicines.2022, 10(5):1170
  • Mediators Inflamm.2016, 2016:7216912
  • Journal of Food and Drug Analysis2023, 31(3), 9.
  • ...
    • 生物活性
    Description: Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of actions for the observed antitumor and antiangiogenic activities of terrestrosin D.
    Targets: VEGFR
    In vitro:
    Pathobiology. 2014;81(3):123-32.
    Terrestrosin D, a steroidal saponin from Tribulus terrestris L., inhibits growth and angiogenesis of human prostate cancer in vitro and in vivo.[Pubmed: 24642631]
    The aim of this study was to investigate whether terrestrosin D (TED) inhibits the progression of castration-resistant prostate cancer and consider its mechanism.
    METHODS AND RESULTS:
    Cell cycle, mitochondrial membrane potential (ΔΨm) and apoptosis were determined by flow cytometry. Caspase-3 activity and vascular endothelial growth factor secretion were detected by a caspase-3 assay and human vascular endothelial growth factor kit, respectively. A PC-3 xenograft mouse model was used to evaluate the anticancer effect of TED in vivo. In vitro, TED strongly suppressed the growth of prostate cancer cells and endothelial cells in a dose-dependent manner. TED induced cell cycle arrest and apoptosis in PC-3 cells and human umbilical vascular endothelial cells (HUVECs). TED-induced apoptosis did not involve the caspase pathway. TED also decreased ΔΨm in PC-3 cells and HUVECs. In vivo, TED significantly suppressed tumor growth in nude mice bearing PC-3 cells, without any overt toxicity. Immunohistochemical analysis showed TED induced apoptotic cell death and inhibited angiogenesis in xenograft tumor cells.
    CONCLUSIONS:
    Cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of actions for the observed antitumor and antiangiogenic activities of TED.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 0.9531 mL 4.7655 mL 9.5311 mL 19.0621 mL 23.8277 mL
    5 mM 0.1906 mL 0.9531 mL 1.9062 mL 3.8124 mL 4.7655 mL
    10 mM 0.0953 mL 0.4766 mL 0.9531 mL 1.9062 mL 2.3828 mL
    50 mM 0.0191 mL 0.0953 mL 0.1906 mL 0.3812 mL 0.4766 mL
    100 mM 0.0095 mL 0.0477 mL 0.0953 mL 0.1906 mL 0.2383 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    重楼皂苷VI; Polyphyllin VI CFN99954 55916-51-3 C39H62O13 = 738.91 20mg QQ客服：1457312923
    Mannioside A; Mannioside A CFN99055 1038922-95-0 C39H62O13 = 738.9 5mg QQ客服：215959384
    麦冬皂苷Ra，麦冬皂苷1，麦冬苷元-3-O-新橙皮糖苷; Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside CFN90638 128502-94-3 C39H62O14 = 754.9 10mg QQ客服：1413575084
    天冬宁B; Shatavarin IV CFN70458 84633-34-1 C45H74O17 = 887.1 5mg QQ客服：215959384
    14-羟基麦冬皂苷C; 14-Hydroxy sprengerinin C CFN90636 1111088-89-1 C44H70O17 = 871.02 10mg QQ客服：215959384
    17-羟基麦冬皂苷C; 17-Hydroxy sprengerinin C CFN90614 1029017-75-1 C44H70O17 = 871.02 10mg QQ客服：3257982914
    麦冬皂苷 C; Sprengerinin C CFN96366 88861-91-0 C44H70O16 = 855.0 5mg QQ客服：1457312923
    2''-O-乙酰麦冬皂苷 C; 2''-O-Acetylsprengerinin C CFN96364 1220707-33-4 C46H72O17 = 897.1 5mg QQ客服：3257982914
    Glucopyranoside,(3beta,25R)-17-hydroxyspirost-5-en-3-yl; Glucopyranoside,(3beta,25R)-17-hydroxyspirost-5-en-3-yl CFN92807 84914-58-9 C44H70O17 = 870.5 10mg QQ客服：3257982914
    重楼皂苷H; Polyphyllin H CFN90701 81917-50-2 C44H70O17 = 871.0 5mg QQ客服：1413575084

    信息支持


    公司简介
    订购流程
    付款方式
    退换货政策

    ChemFaces提供的产品仅用于科学研究使用，不用于诊断或治疗程序。

    联系方式


    电机：027-84237783
    传真：027-84254680
    在线QQ: 1413575084
    E-Mail：manager@chemfaces.com

    湖北省武汉沌口经济技术开区车城南路83号1号楼第三层厂房


    ChemFaces为科学家，科研人员与企业提供快速的产品递送。我们通过瑞士SGS ISO 9001:2008质量体系认证天然化合物与对照品的研发和生产。